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SMAD9 and GRN
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
SMAD9
GRN
Gene Name
SMAD family member 9
granulin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Cytosol
Extracellular Space
Mitochondrion
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity
Metal Ion Binding
Cytokine Activity
Protein Binding
Growth Factor Activity
Poly(A) RNA Binding
Biological Process
Ureteric Bud Development
Response To Hypoxia
Mullerian Duct Regression
Transcription, DNA-templated
Protein Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
BMP Signaling Pathway
Midbrain Development
Hindbrain Development
Intracellular Signal Transduction
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Cartilage Development
Bone Development
Cellular Response To Organic Cyclic Compound
Blastocyst Hatching
Signal Transduction
Embryo Implantation
Positive Regulation Of Epithelial Cell Proliferation
Pathways
Signaling by BMP
Drugs
Diseases
GWAS
Intracranial volume (
22504418
)
Protein-Protein Interactions
117 interactors:
ABTB1
ACTB
ACVR1
AFF1
AP2A1
ARHGAP9
ARID1B
ARNT
ASB2
ASH2L
BAZ1A
BTG2
C10orf2
CAMSAP1
CEP135
CHPF
CLPB
CPXM2
CSH1
CSH2
CTR9
CXXC5
CYP11A1
DIAPH3
DKK1
DNAJA3
DNAJC7
DST
DSTN
E4F1
EIF3C
EIF3E
EIF3F
ERVV-1
EVC2
EXPH5
FLI1
FN1
FTL
GRN
HEY1
HEYL
HUWE1
KDM1A
KDM6A
KIAA0226
KMT2D
LEMD3
LMO4
LNPEP
LRP5
MAN1A2
MAN1C1
MAN2B1
MBD1
MCM3AP
METAP1
MGAT1
MTMR10
MTMR11
NAGK
OTUB1
PABPC4
PAPPA
PELP1
PHKA2
PIR
PKP2
PLEC
PNPLA2
PPARD
PPP2R5E
PRMT6
PSAP
PSMD8
QARS
RANBP9
RFX1
RMND5A
RNF123
RRBP1
SECISBP2
SF3B1
SIL1
SMAD2
SMAD3
SMAD4
SMG1
SNRNP70
SPTBN1
STAG1
SVEP1
TBCD
TERF1
TINAGL1
TMEM57
TOB1
TRIM29
TRIP12
TTC37
UBA6
UBE3A
UBQLN1
UBQLN4
UNC45A
VCPIP1
VPS8
XAB2
YWHAQ
ZEB2
ZNF484
ZNF557
ZNF587
ZNF587B
ZNF592
ZNF83
ZSCAN4
37 interactors:
ARFGAP1
ATN1
ATXN7
CACNA1A
CCDC33
CCNG1
CCNT1
CDK9
CRKL
CRY1
DLK1
DLX2
ELANE
FAM131C
FANCL
FRAT1
GFI1B
GLRX3
HK3
HOXA1
HSPG2
KRT18
KRTAP10-7
KRTAP26-1
NLK
OTX1
PIK3R2
POT1
PRKAB2
RAC1
SGTA
SLPI
SMAD9
TAT
TGM2
TOP3B
YY1
Entrez ID
4093
2896
HPRD ID
04484
00733
Ensembl ID
ENSG00000120693
ENSG00000030582
Uniprot IDs
O15198
P28799
PDB IDs
1G26
2JYE
2JYT
2JYU
2JYV
Enriched GO Terms of Interacting Partners
?
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Gene Expression
Cellular Metabolic Process
Transcription, DNA-templated
Biosynthetic Process
RNA Metabolic Process
RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Cellular Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Gastrulation
Anterior/posterior Pattern Specification
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Developmental Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Multicellular Organismal Development
Atrioventricular Valve Morphogenesis
Endoderm Development
Nitrogen Compound Metabolic Process
Formation Of Primary Germ Layer
Cell Differentiation
Atrioventricular Valve Development
Regulation Of Transcription From RNA Polymerase II Promoter
Anatomical Structure Development
Transcription From RNA Polymerase II Promoter
Organ Development
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Metabolic Process
Embryo Development
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
SMAD Protein Complex Assembly
Posttranscriptional Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Pattern Specification Process
Response To Organic Substance
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Central Nervous System Development
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Cellular Process
Regulation Of Metabolic Process
Brain Development
Regulation Of Kinase Activity
Head Development
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Positive Regulation Of Cellular Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Organic Substance
Transcription, DNA-templated
Regulation Of Cellular Protein Metabolic Process
Pattern Specification Process
RNA Biosynthetic Process
Regulation Of Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
Organ Morphogenesis
Anatomical Structure Morphogenesis
Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Homeostatic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Stimulus
Positive Regulation Of Metabolic Process
Embryonic Organ Morphogenesis
Regulation Of Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Embryonic Skeletal System Development
Response To Light Stimulus
Hindbrain Development
Regulation Of Protein Metabolic Process
Regulation Of Signaling
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Phosphorus Metabolic Process
Pons Development
Cell Surface Receptor Signaling Pathway
Response To Stimulus
Response To Transforming Growth Factor Beta
Positive Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Regulation Of Signal Transduction
Cellular Aromatic Compound Metabolic Process
Central Nervous System Neuron Differentiation
Anatomical Structure Development
Positive Regulation Of Transcription, DNA-templated
Tagcloud
?
arose
backcrosses
bareskin
bsk
chr
clustered
corneal
den
denuded
facility
granulin
hair
intersubspecific
junctional
jup
keratin
kinds
krt1
linkage
mapped
opacity
plakoglobin
portion
rara
recombination
resembling
rex
rim3
spontaneously
Tagcloud (Difference)
?
arose
backcrosses
bareskin
bsk
chr
clustered
corneal
den
denuded
facility
granulin
hair
intersubspecific
junctional
jup
keratin
kinds
krt1
linkage
mapped
opacity
plakoglobin
portion
rara
recombination
resembling
rex
rim3
spontaneously
Tagcloud (Intersection)
?