SMAD9 and UBA6

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		SMAD9	UBA6
Gene Name		SMAD family member 9	ubiquitin-like modifier activating enzyme 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol	Cytoplasm Cytosol
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity Metal Ion Binding	Protein Binding ATP Binding FAT10 Activating Enzyme Activity
	Biological Process	Ureteric Bud Development Response To Hypoxia Mullerian Duct Regression Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway BMP Signaling Pathway Midbrain Development Hindbrain Development Intracellular Signal Transduction Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Cartilage Development Bone Development Cellular Response To Organic Cyclic Compound	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways		Signaling by BMP	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		117 interactors: ABTB1 ACTB ACVR1 AFF1 AP2A1 ARHGAP9 ARID1B ARNT ASB2 ASH2L BAZ1A BTG2 C10orf2 CAMSAP1 CEP135 CHPF CLPB CPXM2 CSH1 CSH2 CTR9 CXXC5 CYP11A1 DIAPH3 DKK1 DNAJA3 DNAJC7 DST DSTN E4F1 EIF3C EIF3E EIF3F ERVV-1 EVC2 EXPH5 FLI1 FN1 FTL GRN HEY1 HEYL HUWE1 KDM1A KDM6A KIAA0226 KMT2D LEMD3 LMO4 LNPEP LRP5 MAN1A2 MAN1C1 MAN2B1 MBD1 MCM3AP METAP1 MGAT1 MTMR10 MTMR11 NAGK OTUB1 PABPC4 PAPPA PELP1 PHKA2 PIR PKP2 PLEC PNPLA2 PPARD PPP2R5E PRMT6 PSAP PSMD8 QARS RANBP9 RFX1 RMND5A RNF123 RRBP1 SECISBP2 SF3B1 SIL1 SMAD2 SMAD3 SMAD4 SMG1 SNRNP70 SPTBN1 STAG1 SVEP1 TBCD TERF1 TINAGL1 TMEM57 TOB1 TRIM29 TRIP12 TTC37 UBA6 UBE3A UBQLN1 UBQLN4 UNC45A VCPIP1 VPS8 XAB2 YWHAQ ZEB2 ZNF484 ZNF557 ZNF587 ZNF587B ZNF592 ZNF83 ZSCAN4	12 interactors: HMBOX1 SMAD9 UBD UBE2D1 UBE2D2 UBE2D3 UBE2G2 UBE2L3 UBE2L6 UBE2S UBE2T UBE2Z
Entrez ID		4093	55236
HPRD ID		04484	13341
Ensembl ID		ENSG00000120693
Uniprot IDs		O15198	A0AVT1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Gene Expression Cellular Metabolic Process Transcription, DNA-templated Biosynthetic Process RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Process Cellular Protein Metabolic Process Protein Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Gastrulation Anterior/posterior Pattern Specification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Developmental Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Atrioventricular Valve Morphogenesis Endoderm Development Nitrogen Compound Metabolic Process Formation Of Primary Germ Layer Cell Differentiation Atrioventricular Valve Development Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transcription From RNA Polymerase II Promoter Organ Development Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Embryo Development Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process SMAD Protein Complex Assembly Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Pattern Specification Process	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Proteolysis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Catabolic Process Protein Metabolic Process Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Protein K6-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Proteasomal Protein Catabolic Process Positive Regulation Of Ligase Activity BMP Signaling Pathway Toll-like Receptor 4 Signaling Pathway Response To Hypoxia Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Innate Immune Response Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Cellular Metabolic Process Activation Of Innate Immune Response Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Innate Immune Response Response To Transforming Growth Factor Beta Protein K63-linked Ubiquitination Regulation Of Protein Ubiquitination Protein Monoubiquitination
Tagcloud ?			adopted annotation artificial bands buffalo concise dodecyl enolase ensure estrous estrus immunoblot indicator insemination lactoperoxidase noninvasive page phases polyacrylamide precisely proteome proteomic saliva sds serotransferrin tgm3 tlr toll transducin
Tagcloud (Difference) ?			adopted annotation artificial bands buffalo concise dodecyl enolase ensure estrous estrus immunoblot indicator insemination lactoperoxidase noninvasive page phases polyacrylamide precisely proteome proteomic saliva sds serotransferrin tgm3 tlr toll transducin
Tagcloud (Intersection) ?