SMAD9 and ZSCAN4

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		SMAD9	ZSCAN4
Gene Name		SMAD family member 9	zinc finger and SCAN domain containing 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol	Nuclear Chromosome, Telomeric Region
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Ureteric Bud Development Response To Hypoxia Mullerian Duct Regression Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway BMP Signaling Pathway Midbrain Development Hindbrain Development Intracellular Signal Transduction Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Cartilage Development Bone Development Cellular Response To Organic Cyclic Compound	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Telomere Maintenance Via Telomere Lengthening
Pathways		Signaling by BMP
Drugs
Diseases
GWAS
Protein-Protein Interactions		117 interactors: ABTB1 ACTB ACVR1 AFF1 AP2A1 ARHGAP9 ARID1B ARNT ASB2 ASH2L BAZ1A BTG2 C10orf2 CAMSAP1 CEP135 CHPF CLPB CPXM2 CSH1 CSH2 CTR9 CXXC5 CYP11A1 DIAPH3 DKK1 DNAJA3 DNAJC7 DST DSTN E4F1 EIF3C EIF3E EIF3F ERVV-1 EVC2 EXPH5 FLI1 FN1 FTL GRN HEY1 HEYL HUWE1 KDM1A KDM6A KIAA0226 KMT2D LEMD3 LMO4 LNPEP LRP5 MAN1A2 MAN1C1 MAN2B1 MBD1 MCM3AP METAP1 MGAT1 MTMR10 MTMR11 NAGK OTUB1 PABPC4 PAPPA PELP1 PHKA2 PIR PKP2 PLEC PNPLA2 PPARD PPP2R5E PRMT6 PSAP PSMD8 QARS RANBP9 RFX1 RMND5A RNF123 RRBP1 SECISBP2 SF3B1 SIL1 SMAD2 SMAD3 SMAD4 SMG1 SNRNP70 SPTBN1 STAG1 SVEP1 TBCD TERF1 TINAGL1 TMEM57 TOB1 TRIM29 TRIP12 TTC37 UBA6 UBE3A UBQLN1 UBQLN4 UNC45A VCPIP1 VPS8 XAB2 YWHAQ ZEB2 ZNF484 ZNF557 ZNF587 ZNF587B ZNF592 ZNF83 ZSCAN4	2 interactors: SMAD1 SMAD9
Entrez ID		4093	201516
HPRD ID		04484	15899
Ensembl ID		ENSG00000120693	ENSG00000180532
Uniprot IDs		O15198	Q8NAM6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Gene Expression Cellular Metabolic Process Transcription, DNA-templated Biosynthetic Process RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Process Cellular Protein Metabolic Process Protein Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Gastrulation Anterior/posterior Pattern Specification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Developmental Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Atrioventricular Valve Morphogenesis Endoderm Development Nitrogen Compound Metabolic Process Formation Of Primary Germ Layer Cell Differentiation Atrioventricular Valve Development Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transcription From RNA Polymerase II Promoter Organ Development Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Embryo Development Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process SMAD Protein Complex Assembly Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Pattern Specification Process	BMP Signaling Pathway Midbrain Development Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Transforming Growth Factor Beta Receptor Signaling Pathway Kidney Epithelium Development Hindbrain Development Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Cartilage Development Bone Development Connective Tissue Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Kidney Development Renal System Development Urogenital System Development Cellular Response To Organic Cyclic Compound Primary MiRNA Processing Skeletal System Development Osteoblast Fate Commitment Mullerian Duct Regression Cellular Response To Growth Factor Stimulus Response To Growth Factor Tube Development SMAD Protein Complex Assembly Brain Development Head Development Mesodermal Cell Fate Commitment Positive Regulation Of Cell Differentiation Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Anatomical Structure Regression Cardiac Muscle Cell Proliferation Central Nervous System Development Production Of MiRNAs Involved In Gene Silencing By MiRNA Cellular Response To BMP Stimulus Epithelium Development Mesodermal Cell Differentiation Cell Fate Commitment Involved In Formation Of Primary Germ Layer Cardiac Muscle Tissue Growth Single Organism Reproductive Process Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Positive Regulation Of Dendrite Morphogenesis Gene Silencing By MiRNA Cellular Response To DsRNA Reproductive Process Positive Regulation Of Transcription, DNA-templated
Tagcloud ?			4q35 affymetrix amongst arrays bmp c2c12 d4z4 dux4 dystrophy ectopically facioscapulohumeral fshd gametogenesis homeobox immortalized ipa muscular myoblasts myod myog myogenesis nrf overlapped profiled rd rhabdomyosarcoma transcriptomic u133 uts2
Tagcloud (Difference) ?			4q35 affymetrix amongst arrays bmp c2c12 d4z4 dux4 dystrophy ectopically facioscapulohumeral fshd gametogenesis homeobox immortalized ipa muscular myoblasts myod myog myogenesis nrf overlapped profiled rd rhabdomyosarcoma transcriptomic u133 uts2
Tagcloud (Intersection) ?