GRN and CCNG1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GRN	CCNG1
Gene Name		granulin	cyclin G1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Mitochondrion Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Nucleus Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Cytokine Activity Protein Binding Growth Factor Activity Poly(A) RNA Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Blastocyst Hatching Signal Transduction Embryo Implantation Positive Regulation Of Epithelial Cell Proliferation	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Syncytium Formation Mitotic Nuclear Division Mitotic G2 DNA Damage Checkpoint Brain Development Response To Organonitrogen Compound Cell Growth Negative Regulation Of Apoptotic Process Cell Division
Pathways
Drugs
Diseases
GWAS		Intracranial volume ( 22504418)
Protein-Protein Interactions		37 interactors: ARFGAP1 ATN1 ATXN7 CACNA1A CCDC33 CCNG1 CCNT1 CDK9 CRKL CRY1 DLK1 DLX2 ELANE FAM131C FANCL FRAT1 GFI1B GLRX3 HK3 HOXA1 HSPG2 KRT18 KRTAP10-7 KRTAP26-1 NLK OTX1 PIK3R2 POT1 PRKAB2 RAC1 SGTA SLPI SMAD9 TAT TGM2 TOP3B YY1	25 interactors: APP CDK5 CDKN2A COX2 GAK GRN HMBOX1 KRT40 KRTAP10-7 LTBP3 LZTS2 MDM2 NFATC4 PAK7 PLEKHA4 PNMA1 PPP2CA PPP2R4 RBPMS SHKBP1 SPERT TFAP2C TFIP11 TNIP1 TP53
Entrez ID		2896	900
HPRD ID		00733	03345
Ensembl ID		ENSG00000030582	ENSG00000113328
Uniprot IDs		P28799	P51959
PDB IDs		1G26 2JYE 2JYT 2JYU 2JYV
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Central Nervous System Development Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cellular Process Regulation Of Metabolic Process Brain Development Regulation Of Kinase Activity Head Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Transcription, DNA-templated Regulation Of Cellular Protein Metabolic Process Pattern Specification Process RNA Biosynthetic Process Regulation Of Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Organ Morphogenesis Anatomical Structure Morphogenesis Biosynthetic Process Negative Regulation Of Biosynthetic Process Homeostatic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Metabolic Process Embryonic Organ Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Embryonic Skeletal System Development Response To Light Stimulus Hindbrain Development Regulation Of Protein Metabolic Process Regulation Of Signaling Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Phosphorus Metabolic Process Pons Development Cell Surface Receptor Signaling Pathway Response To Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Regulation Of Signal Transduction Cellular Aromatic Compound Metabolic Process Central Nervous System Neuron Differentiation Anatomical Structure Development Positive Regulation Of Transcription, DNA-templated	Positive Regulation Of Cellular Metabolic Process Cellular Response To UV Response To Light Stimulus Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Signal Transduction Regulation Of Nucleocytoplasmic Transport Apoptotic Process Cellular Response To Light Stimulus Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Arrest Programmed Cell Death Regulation Of Intracellular Transport Positive Regulation Of Intracellular Transport Cell Death Response To Radiation Death Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Regulation Of Cell Proliferation Regulation Of Protein Export From Nucleus Regulation Of Intracellular Protein Transport Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Regulation Of Cell Death Regulation Of Protein Localization Response To UV Cellular Response To Radiation Learning Positive Regulation Of Protein Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Aging Negative Regulation Of Cell Growth Positive Regulation Of Intracellular Protein Transport Cell Cycle Neuron Apoptotic Process Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Regulation Of Cellular Localization Neuron Death Regulation Of Phosphorus Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Cell Cycle Arrest Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Negative Regulation Of Cell Cycle
Tagcloud ?		arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin hair intersubspecific junctional jup keratin kinds krt1 linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously	abcb4 akr7a3 anabolic bioassay built carcinogenic carcinogenicity carcinogens cdkn1a dataset datasets employs formally gates generalizable informative integrates mathematical methodologies nongenotoxic omics phlda3 rankings reproducible rodent signatures subsamplings toxicogenomics virtue
Tagcloud (Difference) ?		arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin hair intersubspecific junctional jup keratin kinds krt1 linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously	abcb4 akr7a3 anabolic bioassay built carcinogenic carcinogenicity carcinogens cdkn1a dataset datasets employs formally gates generalizable informative integrates mathematical methodologies nongenotoxic omics phlda3 rankings reproducible rodent signatures subsamplings toxicogenomics virtue
Tagcloud (Intersection) ?