SMAD9 and PIR

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		SMAD9	PIR
Gene Name		SMAD family member 9	pirin (iron-binding nuclear protein)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity Metal Ion Binding	Transcription Cofactor Activity Protein Binding Quercetin 2,3-dioxygenase Activity Metal Ion Binding
	Biological Process	Ureteric Bud Development Response To Hypoxia Mullerian Duct Regression Transcription, DNA-templated Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway BMP Signaling Pathway Midbrain Development Hindbrain Development Intracellular Signal Transduction Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Cartilage Development Bone Development Cellular Response To Organic Cyclic Compound	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Monocyte Differentiation Oxidation-reduction Process
Pathways		Signaling by BMP
Drugs
Diseases
GWAS
Protein-Protein Interactions		117 interactors: ABTB1 ACTB ACVR1 AFF1 AP2A1 ARHGAP9 ARID1B ARNT ASB2 ASH2L BAZ1A BTG2 C10orf2 CAMSAP1 CEP135 CHPF CLPB CPXM2 CSH1 CSH2 CTR9 CXXC5 CYP11A1 DIAPH3 DKK1 DNAJA3 DNAJC7 DST DSTN E4F1 EIF3C EIF3E EIF3F ERVV-1 EVC2 EXPH5 FLI1 FN1 FTL GRN HEY1 HEYL HUWE1 KDM1A KDM6A KIAA0226 KMT2D LEMD3 LMO4 LNPEP LRP5 MAN1A2 MAN1C1 MAN2B1 MBD1 MCM3AP METAP1 MGAT1 MTMR10 MTMR11 NAGK OTUB1 PABPC4 PAPPA PELP1 PHKA2 PIR PKP2 PLEC PNPLA2 PPARD PPP2R5E PRMT6 PSAP PSMD8 QARS RANBP9 RFX1 RMND5A RNF123 RRBP1 SECISBP2 SF3B1 SIL1 SMAD2 SMAD3 SMAD4 SMG1 SNRNP70 SPTBN1 STAG1 SVEP1 TBCD TERF1 TINAGL1 TMEM57 TOB1 TRIM29 TRIP12 TTC37 UBA6 UBE3A UBQLN1 UBQLN4 UNC45A VCPIP1 VPS8 XAB2 YWHAQ ZEB2 ZNF484 ZNF557 ZNF587 ZNF587B ZNF592 ZNF83 ZSCAN4	4 interactors: BCL3 NFIX NFKBIA SMAD9
Entrez ID		4093	8544
HPRD ID		04484	04510
Ensembl ID		ENSG00000120693	ENSG00000087842
Uniprot IDs		O15198	O00625
PDB IDs			1J1L 3ACL 4ERO 4EWA 4EWD 4EWE 4GUL 4HLT
Enriched GO Terms of Interacting Partners?		Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Gene Expression Cellular Metabolic Process Transcription, DNA-templated Biosynthetic Process RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Process Cellular Protein Metabolic Process Protein Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Gastrulation Anterior/posterior Pattern Specification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Developmental Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Atrioventricular Valve Morphogenesis Endoderm Development Nitrogen Compound Metabolic Process Formation Of Primary Germ Layer Cell Differentiation Atrioventricular Valve Development Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transcription From RNA Polymerase II Promoter Organ Development Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Metabolic Process Embryo Development Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process SMAD Protein Complex Assembly Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Pattern Specification Process	Protein Import Into Nucleus, Translocation Positive Regulation Of Transcription, DNA-templated Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of DNA Binding Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Cellular Metabolic Process Protein Import Into Nucleus Nuclear Import Maintenance Of Protein Location In Cell Maintenance Of Protein Location Maintenance Of Location In Cell Protein Import Regulation Of Protein Import Into Nucleus Protein Localization To Nucleus Hindbrain Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Positive Regulation Of Interleukin-10 Biosynthetic Process Response To Abiotic Stimulus Regulation Of Protein Localization To Nucleus Positive Regulation Of Metabolic Process Regulation Of Nucleocytoplasmic Transport Regulation Of I-kappaB Kinase/NF-kappaB Signaling Follicular Dendritic Cell Differentiation T-helper 2 Cell Differentiation Regulation Of Binding Regulation Of Intracellular Protein Transport Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Interleukin-8 Biosynthetic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Marginal Zone B Cell Differentiation Cytoplasmic Sequestering Of NF-kappaB Cellular Response To Cold Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mullerian Duct Regression Establishment Of Protein Localization To Organelle Regulation Of RNA Metabolic Process Positive Regulation Of Cytokine Production Type 2 Immune Response Protein Targeting Intracellular Signal Transduction Regulation Of Gene Expression
Tagcloud ?			125i alpha2 blast cleave columns conditioned dependently digest facilitating film gccm genbank germ homogeneity hydrolyzing intertesticular junction kda kyefyeixll macroglobulin nh2 postulated protease proteolysis secretory sertoli testes testin tryptic
Tagcloud (Difference) ?			125i alpha2 blast cleave columns conditioned dependently digest facilitating film gccm genbank germ homogeneity hydrolyzing intertesticular junction kda kyefyeixll macroglobulin nh2 postulated protease proteolysis secretory sertoli testes testin tryptic
Tagcloud (Intersection) ?