GRN and SGTA

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		GRN	SGTA
Gene Name		granulin	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Mitochondrion Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	Cytokine Activity Protein Binding Growth Factor Activity Poly(A) RNA Binding	Protein Binding
	Biological Process	Blastocyst Hatching Signal Transduction Embryo Implantation Positive Regulation Of Epithelial Cell Proliferation	Biological_process Viral Process
Pathways
Drugs
Diseases
GWAS		Intracranial volume ( 22504418)
Protein-Protein Interactions		37 interactors: ARFGAP1 ATN1 ATXN7 CACNA1A CCDC33 CCNG1 CCNT1 CDK9 CRKL CRY1 DLK1 DLX2 ELANE FAM131C FANCL FRAT1 GFI1B GLRX3 HK3 HOXA1 HSPG2 KRT18 KRTAP10-7 KRTAP26-1 NLK OTX1 PIK3R2 POT1 PRKAB2 RAC1 SGTA SLPI SMAD9 TAT TGM2 TOP3B YY1	92 interactors: ADIPOQ AGR3 BAG6 BCL2L12 C1QA C1QTNF1 C1QTNF6 C3orf52 CARKD CCDC155 CD79B CD99 CDH15 COL1A2 COL8A2 CSF1 CST1 CTSL CXCL8 EFEMP1 EFEMP2 ERP27 EVA1B F11R FERD3L FIP1L1 FKBP7 FXYD7 GABARAPL2 GAL GHR GIP GPX7 GRN GYPA HSP90AA1 HSP90AB1 HSPA13 HSPA8 IGL IGLC1 IRF3 IRF5 ITPRIPL1 KRT6A KTN1 LAIR2 LAT MSMB MSTN MYDGF NME3 NXF1 PBXIP1 PCDHA4 PFN2 PIAS1 PPIB PPIC PPP1R3C PRAP1 PTN RARRES3 RPN1 SDC4 SERPINE1 SGCA SLPI SMAGP SOD3 SPP1 SPPL2A SRGN SYT11 SYT4 TFF3 TFRC TGFA TMEM174 TMEM31 TMPO TMUB2 TNFRSF13B TNFRSF1A TWSG1 TXNDC12 UBL4A UPK3A VIP WBP1L ZG16 ZG16B
Entrez ID		2896	6449
HPRD ID		00733	04568
Ensembl ID		ENSG00000030582	ENSG00000104969
Uniprot IDs		P28799	O43765
PDB IDs		1G26 2JYE 2JYT 2JYU 2JYV	2VYI 4GOD 4GOE 4GOF
Enriched GO Terms of Interacting Partners?		Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Central Nervous System Development Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cellular Process Regulation Of Metabolic Process Brain Development Regulation Of Kinase Activity Head Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Transcription, DNA-templated Regulation Of Cellular Protein Metabolic Process Pattern Specification Process RNA Biosynthetic Process Regulation Of Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Organ Morphogenesis Anatomical Structure Morphogenesis Biosynthetic Process Negative Regulation Of Biosynthetic Process Homeostatic Process Negative Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Metabolic Process Embryonic Organ Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Embryonic Skeletal System Development Response To Light Stimulus Hindbrain Development Regulation Of Protein Metabolic Process Regulation Of Signaling Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Phosphorus Metabolic Process Pons Development Cell Surface Receptor Signaling Pathway Response To Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Regulation Of Signal Transduction Cellular Aromatic Compound Metabolic Process Central Nervous System Neuron Differentiation Anatomical Structure Development Positive Regulation Of Transcription, DNA-templated	Response To Stress Protein Heterotrimerization Extracellular Matrix Organization Extracellular Structure Organization Defense Response Regulation Of Immune System Process Protein Trimerization Macrophage Apoptotic Process Response To Wounding Regulation Of Secretion Immune System Process Regulation Of Protein Metabolic Process Anatomical Structure Development Regulation Of Cell Proliferation Protein Heterooligomerization Cell Communication Cell Surface Receptor Signaling Pathway Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Immune System Process Wound Healing Regulation Of Cellular Protein Metabolic Process Signaling Regulation Of Cellular Response To Heat Negative Regulation Of Proteolysis Positive Regulation Of Protein Modification Process Negative Regulation Of Protein Processing Developmental Process Multicellular Organismal Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Innate Immune Response Cellular Response To Stimulus Regulation Of Cytokine-mediated Signaling Pathway Extracellular Matrix Disassembly Myeloid Cell Apoptotic Process Response To Organic Substance Protein Folding Regulation Of Protein Processing Response To Lipid Regulation Of Developmental Growth Protein Insertion Into ER Membrane Inflammatory Cell Apoptotic Process Positive Regulation Of Cellular Metabolic Process System Development Regulation Of Immune Response Inflammatory Response Signal Transduction Positive Regulation Of Protein Metabolic Process
Tagcloud ?		arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin hair intersubspecific junctional jup keratin kinds krt1 linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously	bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Difference) ?		arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin hair intersubspecific junctional jup keratin kinds krt1 linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously	bag6 biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Intersection) ?