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SMAD9 and FLI1
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
SMAD9
FLI1
Gene Name
SMAD family member 9
Fli-1 proto-oncogene, ETS transcription factor
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Cytosol
Nucleus
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity
Metal Ion Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding
Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
DNA Binding
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
Biological Process
Ureteric Bud Development
Response To Hypoxia
Mullerian Duct Regression
Transcription, DNA-templated
Protein Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
BMP Signaling Pathway
Midbrain Development
Hindbrain Development
Intracellular Signal Transduction
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Cartilage Development
Bone Development
Cellular Response To Organic Cyclic Compound
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription From RNA Polymerase II Promoter
Hemostasis
Blood Circulation
Organ Morphogenesis
Cell Differentiation
Megakaryocyte Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Signaling by BMP
Drugs
Diseases
GWAS
Height (
20881960
)
Myopia (pathological) (
23049088
)
Rheumatoid arthritis (
22446963
)
Protein-Protein Interactions
117 interactors:
ABTB1
ACTB
ACVR1
AFF1
AP2A1
ARHGAP9
ARID1B
ARNT
ASB2
ASH2L
BAZ1A
BTG2
C10orf2
CAMSAP1
CEP135
CHPF
CLPB
CPXM2
CSH1
CSH2
CTR9
CXXC5
CYP11A1
DIAPH3
DKK1
DNAJA3
DNAJC7
DST
DSTN
E4F1
EIF3C
EIF3E
EIF3F
ERVV-1
EVC2
EXPH5
FLI1
FN1
FTL
GRN
HEY1
HEYL
HUWE1
KDM1A
KDM6A
KIAA0226
KMT2D
LEMD3
LMO4
LNPEP
LRP5
MAN1A2
MAN1C1
MAN2B1
MBD1
MCM3AP
METAP1
MGAT1
MTMR10
MTMR11
NAGK
OTUB1
PABPC4
PAPPA
PELP1
PHKA2
PIR
PKP2
PLEC
PNPLA2
PPARD
PPP2R5E
PRMT6
PSAP
PSMD8
QARS
RANBP9
RFX1
RMND5A
RNF123
RRBP1
SECISBP2
SF3B1
SIL1
SMAD2
SMAD3
SMAD4
SMG1
SNRNP70
SPTBN1
STAG1
SVEP1
TBCD
TERF1
TINAGL1
TMEM57
TOB1
TRIM29
TRIP12
TTC37
UBA6
UBE3A
UBQLN1
UBQLN4
UNC45A
VCPIP1
VPS8
XAB2
YWHAQ
ZEB2
ZNF484
ZNF557
ZNF587
ZNF587B
ZNF592
ZNF83
ZSCAN4
19 interactors:
BRCA1
CTBP2
ELK1
ERG
ETV6
EWSR1
GATA1
KLF1
PIAS1
PIAS2
PRKCD
SIAH1
SMAD3
SMAD9
SOX30
SRF
SUMO1
TDP2
UBE2I
Entrez ID
4093
2313
HPRD ID
04484
01901
Ensembl ID
ENSG00000120693
ENSG00000151702
Uniprot IDs
O15198
Q01543
PDB IDs
1FLI
1X66
2YTU
Enriched GO Terms of Interacting Partners
?
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Gene Expression
Cellular Metabolic Process
Transcription, DNA-templated
Biosynthetic Process
RNA Metabolic Process
RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Cellular Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Gastrulation
Anterior/posterior Pattern Specification
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Developmental Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Multicellular Organismal Development
Atrioventricular Valve Morphogenesis
Endoderm Development
Nitrogen Compound Metabolic Process
Formation Of Primary Germ Layer
Cell Differentiation
Atrioventricular Valve Development
Regulation Of Transcription From RNA Polymerase II Promoter
Anatomical Structure Development
Transcription From RNA Polymerase II Promoter
Organ Development
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Metabolic Process
Embryo Development
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
SMAD Protein Complex Assembly
Posttranscriptional Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Pattern Specification Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Transcription, DNA-templated
RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Heterocycle Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Aromatic Compound Metabolic Process
Protein Sumoylation
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
RNA Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Negative Regulation Of Biosynthetic Process
Cellular Response To Organic Substance
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Response To Organic Substance
Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Cellular Metabolic Process
Regulation Of Binding
Regulation Of Cellular Process
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Androgen Receptor Signaling Pathway
Regulation Of Signaling
Erythrocyte Development
Protein Modification By Small Protein Conjugation
Regulation Of Signal Transduction
Intracellular Steroid Hormone Receptor Signaling Pathway
Developmental Process
Metabolic Process
Peptidyl-lysine Modification
Peptidyl-amino Acid Modification
Tagcloud
?
antitrypsin
chn
chondrosarcoma
desmin
desmoplastic
ectomesenchymoma
etv1
ews
extraskeletal
fkhr
hhf35
liposarcoma
mic2
myod1
myxoid
p22
pax
pnet
q12
q14
q22
q24
q35
ssx1
stt
stts
syt
tec
witnessed
Tagcloud (Difference)
?
antitrypsin
chn
chondrosarcoma
desmin
desmoplastic
ectomesenchymoma
etv1
ews
extraskeletal
fkhr
hhf35
liposarcoma
mic2
myod1
myxoid
p22
pax
pnet
q12
q14
q22
q24
q35
ssx1
stt
stts
syt
tec
witnessed
Tagcloud (Intersection)
?