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SMAD9 and PNPLA2
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
HPRD
(two hybrid)
SMAD9
PNPLA2
Gene Name
SMAD family member 9
patatin-like phospholipase domain containing 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Cytosol
Endoplasmic Reticulum Membrane
Lipid Particle
Cytosol
Plasma Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity
Metal Ion Binding
Triglyceride Lipase Activity
Biological Process
Ureteric Bud Development
Response To Hypoxia
Mullerian Duct Regression
Transcription, DNA-templated
Protein Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
BMP Signaling Pathway
Midbrain Development
Hindbrain Development
Intracellular Signal Transduction
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Cartilage Development
Bone Development
Cellular Response To Organic Cyclic Compound
Phospholipid Metabolic Process
Negative Regulation Of Sequestering Of Triglyceride
Positive Regulation Of Triglyceride Catabolic Process
Triglyceride Catabolic Process
Lipid Storage
Lipid Particle Organization
Acylglycerol Acyl-chain Remodeling
Small Molecule Metabolic Process
Glycerophospholipid Biosynthetic Process
Pathways
Signaling by BMP
Metabolism of lipids and lipoproteins
Acyl chain remodeling of DAG and TAG
Phospholipid metabolism
Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions
117 interactors:
ABTB1
ACTB
ACVR1
AFF1
AP2A1
ARHGAP9
ARID1B
ARNT
ASB2
ASH2L
BAZ1A
BTG2
C10orf2
CAMSAP1
CEP135
CHPF
CLPB
CPXM2
CSH1
CSH2
CTR9
CXXC5
CYP11A1
DIAPH3
DKK1
DNAJA3
DNAJC7
DST
DSTN
E4F1
EIF3C
EIF3E
EIF3F
ERVV-1
EVC2
EXPH5
FLI1
FN1
FTL
GRN
HEY1
HEYL
HUWE1
KDM1A
KDM6A
KIAA0226
KMT2D
LEMD3
LMO4
LNPEP
LRP5
MAN1A2
MAN1C1
MAN2B1
MBD1
MCM3AP
METAP1
MGAT1
MTMR10
MTMR11
NAGK
OTUB1
PABPC4
PAPPA
PELP1
PHKA2
PIR
PKP2
PLEC
PNPLA2
PPARD
PPP2R5E
PRMT6
PSAP
PSMD8
QARS
RANBP9
RFX1
RMND5A
RNF123
RRBP1
SECISBP2
SF3B1
SIL1
SMAD2
SMAD3
SMAD4
SMG1
SNRNP70
SPTBN1
STAG1
SVEP1
TBCD
TERF1
TINAGL1
TMEM57
TOB1
TRIM29
TRIP12
TTC37
UBA6
UBE3A
UBQLN1
UBQLN4
UNC45A
VCPIP1
VPS8
XAB2
YWHAQ
ZEB2
ZNF484
ZNF557
ZNF587
ZNF587B
ZNF592
ZNF83
ZSCAN4
10 interactors:
ABHD5
ARFGEF2
CYTH2
FAF2
GBF1
MARK3
PHYHIP
SERPINF1
SMAD9
UBE2R2
Entrez ID
4093
57104
HPRD ID
04484
11443
Ensembl ID
ENSG00000120693
ENSG00000177666
Uniprot IDs
O15198
Q96AD5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Gene Expression
Cellular Metabolic Process
Transcription, DNA-templated
Biosynthetic Process
RNA Metabolic Process
RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Cellular Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Gastrulation
Anterior/posterior Pattern Specification
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Developmental Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Multicellular Organismal Development
Atrioventricular Valve Morphogenesis
Endoderm Development
Nitrogen Compound Metabolic Process
Formation Of Primary Germ Layer
Cell Differentiation
Atrioventricular Valve Development
Regulation Of Transcription From RNA Polymerase II Promoter
Anatomical Structure Development
Transcription From RNA Polymerase II Promoter
Organ Development
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Metabolic Process
Embryo Development
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
SMAD Protein Complex Assembly
Posttranscriptional Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Pattern Specification Process
Regulation Of ARF Protein Signal Transduction
Regulation Of Catalytic Activity
Positive Regulation Of Hydrolase Activity
Post-Golgi Vesicle-mediated Transport
Cellular Response To Cobalt Ion
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Catalytic Activity
Negative Regulation Of Sequestering Of Triglyceride
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Triglyceride Catabolic Process
Regulation Of GTPase Activity
Mullerian Duct Regression
Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Receptor Recycling
Response To Cobalt Ion
Golgi Vesicle Transport
Short-term Memory
COPI-coated Vesicle Budding
Positive Regulation Of Lipoprotein Lipase Activity
COPI Coating Of Golgi Vesicle
Positive Regulation Of Metabolic Process
Tagcloud
?
abhd5
agpat2
anomaly
atgl
cgi
ctgm
dgat1
diverge
enteropathy
gk
glycerol
gpd1
hsl
ichthyosis
inborn
jordan
lipe
lipodystrophy
loosing
lpin1
lpin2
majeed
nlsd
perilipin
pseudohypertriglyceridemia
rhabdomyolysis
steatosis
tgs
vacuolated
Tagcloud (Difference)
?
abhd5
agpat2
anomaly
atgl
cgi
ctgm
dgat1
diverge
enteropathy
gk
glycerol
gpd1
hsl
ichthyosis
inborn
jordan
lipe
lipodystrophy
loosing
lpin1
lpin2
majeed
nlsd
perilipin
pseudohypertriglyceridemia
rhabdomyolysis
steatosis
tgs
vacuolated
Tagcloud (Intersection)
?