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SMAD9 and PSAP
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
HPRD
(two hybrid)
SMAD9
PSAP
Gene Name
SMAD family member 9
prosaposin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Cytosol
Extracellular Region
Extracellular Space
Nucleoplasm
Nucleolus
Mitochondrion
Lysosomal Membrane
Golgi Apparatus
Integral Component Of Membrane
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity
Metal Ion Binding
Protein Binding
Enzyme Activator Activity
Lipid Binding
Biological Process
Ureteric Bud Development
Response To Hypoxia
Mullerian Duct Regression
Transcription, DNA-templated
Protein Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
BMP Signaling Pathway
Midbrain Development
Hindbrain Development
Intracellular Signal Transduction
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Cartilage Development
Bone Development
Cellular Response To Organic Cyclic Compound
Platelet Degranulation
Sphingolipid Metabolic Process
Glycosphingolipid Metabolic Process
Lipid Transport
Blood Coagulation
Regulation Of Lipid Metabolic Process
Platelet Activation
Positive Regulation Of Catalytic Activity
Regulation Of MAPK Cascade
Small Molecule Metabolic Process
Prostate Gland Growth
Epithelial Cell Differentiation Involved In Prostate Gland Development
Cellular Response To Organic Substance
Pathways
Signaling by BMP
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Sphingolipid metabolism
Metabolism of lipids and lipoproteins
Glycosphingolipid metabolism
Class A/1 (Rhodopsin-like receptors)
Platelet degranulation
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Peptide ligand-binding receptors
Response to elevated platelet cytosolic Ca2+
Platelet activation, signaling and aggregation
Drugs
Di-Stearoyl-3-Sn-Phosphatidylethanolamine
Diseases
GWAS
Protein-Protein Interactions
117 interactors:
ABTB1
ACTB
ACVR1
AFF1
AP2A1
ARHGAP9
ARID1B
ARNT
ASB2
ASH2L
BAZ1A
BTG2
C10orf2
CAMSAP1
CEP135
CHPF
CLPB
CPXM2
CSH1
CSH2
CTR9
CXXC5
CYP11A1
DIAPH3
DKK1
DNAJA3
DNAJC7
DST
DSTN
E4F1
EIF3C
EIF3E
EIF3F
ERVV-1
EVC2
EXPH5
FLI1
FN1
FTL
GRN
HEY1
HEYL
HUWE1
KDM1A
KDM6A
KIAA0226
KMT2D
LEMD3
LMO4
LNPEP
LRP5
MAN1A2
MAN1C1
MAN2B1
MBD1
MCM3AP
METAP1
MGAT1
MTMR10
MTMR11
NAGK
OTUB1
PABPC4
PAPPA
PELP1
PHKA2
PIR
PKP2
PLEC
PNPLA2
PPARD
PPP2R5E
PRMT6
PSAP
PSMD8
QARS
RANBP9
RFX1
RMND5A
RNF123
RRBP1
SECISBP2
SF3B1
SIL1
SMAD2
SMAD3
SMAD4
SMG1
SNRNP70
SPTBN1
STAG1
SVEP1
TBCD
TERF1
TINAGL1
TMEM57
TOB1
TRIM29
TRIP12
TTC37
UBA6
UBE3A
UBQLN1
UBQLN4
UNC45A
VCPIP1
VPS8
XAB2
YWHAQ
ZEB2
ZNF484
ZNF557
ZNF587
ZNF587B
ZNF592
ZNF83
ZSCAN4
14 interactors:
BACE1
BRCA1
CD1B
CELSR1
COPS6
CTSD
GBA
MAFF
SGK223
SMAD2
SMAD9
UBE3A
USP4
ZBED1
Entrez ID
4093
5660
HPRD ID
04484
01460
Ensembl ID
ENSG00000120693
ENSG00000197746
Uniprot IDs
O15198
P07602
PDB IDs
1M12
1N69
1SN6
2DOB
2GTG
2QYP
2R0R
2R1Q
2RB3
2Z9A
3BQP
3BQQ
4DDJ
Enriched GO Terms of Interacting Partners
?
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Gene Expression
Cellular Metabolic Process
Transcription, DNA-templated
Biosynthetic Process
RNA Metabolic Process
RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Cellular Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Gastrulation
Anterior/posterior Pattern Specification
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Developmental Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Multicellular Organismal Development
Atrioventricular Valve Morphogenesis
Endoderm Development
Nitrogen Compound Metabolic Process
Formation Of Primary Germ Layer
Cell Differentiation
Atrioventricular Valve Development
Regulation Of Transcription From RNA Polymerase II Promoter
Anatomical Structure Development
Transcription From RNA Polymerase II Promoter
Organ Development
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Metabolic Process
Embryo Development
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
SMAD Protein Complex Assembly
Posttranscriptional Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Pattern Specification Process
Regulation Of Protein Ubiquitination
Androgen Receptor Signaling Pathway
Protein Autoubiquitination
Positive Regulation Of Histone H4-K20 Methylation
Sperm Entry
Positive Regulation Of Histone H4-K16 Acetylation
Protein Localization Involved In Establishment Of Planar Polarity
Intracellular Steroid Hormone Receptor Signaling Pathway
Chordate Embryonic Development
Embryo Development Ending In Birth Or Egg Hatching
Cellular Protein Modification Process
Protein Metabolic Process
Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Establishment Of Body Hair Planar Orientation
Positive Regulation Of Histone H3-K9 Acetylation
Lateral Sprouting Involved In Lung Morphogenesis
Orthogonal Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis
Planar Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Morphogenesis
Glucosylceramide Catabolic Process
Urogenital System Development
Response To Organic Cyclic Compound
Cellular Response To Organic Cyclic Compound
Organ Growth
Cellular Response To Tumor Necrosis Factor
Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Zygotic Specification Of Dorsal/ventral Axis
Ureteric Bud Development
Mesonephric Tubule Development
Mesonephric Epithelium Development
Protein Modification By Small Protein Removal
Dichotomous Subdivision Of Terminal Units Involved In Lung Branching
Mesonephros Development
Response To Tumor Necrosis Factor
Glucosylceramide Metabolic Process
Cellular Response To Indole-3-methanol
Establishment Of Planar Polarity Of Embryonic Epithelium
Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Mesoderm Development
Negative Regulation Of Centriole Replication
Primary MiRNA Processing
Sphingosine Biosynthetic Process
Embryo Development
Kidney Epithelium Development
Dosage Compensation By Inactivation Of X Chromosome
Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Regulation Of Nodal Signaling Pathway
Common-partner SMAD Protein Phosphorylation
Sphingoid Biosynthetic Process
Tagcloud
?
ac
acinar
adenocarcinoma
cdx2
cea
ck20
ck7
dac
debated
erg
gleason
hmwck
immunomarkers
ki
lysozyme
morphotypes
overlap
p16
p504s
p63
patchy
pax
prolactin
prostatic
prostein
psma
slides
villin
Tagcloud (Difference)
?
ac
acinar
adenocarcinoma
cdx2
cea
ck20
ck7
dac
debated
erg
gleason
hmwck
immunomarkers
ki
lysozyme
morphotypes
overlap
p16
p504s
p63
patchy
pax
prolactin
prostatic
prostein
psma
slides
villin
Tagcloud (Intersection)
?