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SMAD9 and ARHGAP9
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
HPRD
(two hybrid)
SMAD9
ARHGAP9
Gene Name
SMAD family member 9
Rho GTPase activating protein 9
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Cytosol
Cytosol
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Transforming Growth Factor Beta Receptor, Pathway-specific Cytoplasmic Mediator Activity
Metal Ion Binding
GTPase Activator Activity
Phosphatidylinositol-3,4,5-trisphosphate Binding
Biological Process
Ureteric Bud Development
Response To Hypoxia
Mullerian Duct Regression
Transcription, DNA-templated
Protein Phosphorylation
Transforming Growth Factor Beta Receptor Signaling Pathway
BMP Signaling Pathway
Midbrain Development
Hindbrain Development
Intracellular Signal Transduction
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Cartilage Development
Bone Development
Cellular Response To Organic Cyclic Compound
Small GTPase Mediated Signal Transduction
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Pathways
Signaling by BMP
Rho GTPase cycle
Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions
117 interactors:
ABTB1
ACTB
ACVR1
AFF1
AP2A1
ARHGAP9
ARID1B
ARNT
ASB2
ASH2L
BAZ1A
BTG2
C10orf2
CAMSAP1
CEP135
CHPF
CLPB
CPXM2
CSH1
CSH2
CTR9
CXXC5
CYP11A1
DIAPH3
DKK1
DNAJA3
DNAJC7
DST
DSTN
E4F1
EIF3C
EIF3E
EIF3F
ERVV-1
EVC2
EXPH5
FLI1
FN1
FTL
GRN
HEY1
HEYL
HUWE1
KDM1A
KDM6A
KIAA0226
KMT2D
LEMD3
LMO4
LNPEP
LRP5
MAN1A2
MAN1C1
MAN2B1
MBD1
MCM3AP
METAP1
MGAT1
MTMR10
MTMR11
NAGK
OTUB1
PABPC4
PAPPA
PELP1
PHKA2
PIR
PKP2
PLEC
PNPLA2
PPARD
PPP2R5E
PRMT6
PSAP
PSMD8
QARS
RANBP9
RFX1
RMND5A
RNF123
RRBP1
SECISBP2
SF3B1
SIL1
SMAD2
SMAD3
SMAD4
SMG1
SNRNP70
SPTBN1
STAG1
SVEP1
TBCD
TERF1
TINAGL1
TMEM57
TOB1
TRIM29
TRIP12
TTC37
UBA6
UBE3A
UBQLN1
UBQLN4
UNC45A
VCPIP1
VPS8
XAB2
YWHAQ
ZEB2
ZNF484
ZNF557
ZNF587
ZNF587B
ZNF592
ZNF83
ZSCAN4
6 interactors:
APP
FASLG
FHL2
GRB2
RBPMS
SMAD9
Entrez ID
4093
64333
HPRD ID
04484
06449
Ensembl ID
ENSG00000120693
ENSG00000123329
Uniprot IDs
O15198
J3KPQ4
Q9BRR9
PDB IDs
2P0D
2P0F
2P0H
Enriched GO Terms of Interacting Partners
?
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Gene Expression
Cellular Metabolic Process
Transcription, DNA-templated
Biosynthetic Process
RNA Metabolic Process
RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Cellular Process
Cellular Protein Metabolic Process
Protein Metabolic Process
Regulation Of Gene Expression
Nucleobase-containing Compound Metabolic Process
Gastrulation
Anterior/posterior Pattern Specification
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Gene Expression
Developmental Process
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Multicellular Organismal Development
Atrioventricular Valve Morphogenesis
Endoderm Development
Nitrogen Compound Metabolic Process
Formation Of Primary Germ Layer
Cell Differentiation
Atrioventricular Valve Development
Regulation Of Transcription From RNA Polymerase II Promoter
Anatomical Structure Development
Transcription From RNA Polymerase II Promoter
Organ Development
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Metabolic Process
Embryo Development
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
SMAD Protein Complex Assembly
Posttranscriptional Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Pattern Specification Process
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Metabolic Process
Anatomical Structure Morphogenesis
Organ Development
RNA Metabolic Process
Response To Growth Factor
Gene Expression
Cell Development
Regulation Of Transcription From RNA Polymerase II Promoter
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Peptidase Activity
Collateral Sprouting In Absence Of Injury
Atrial Cardiac Muscle Cell Development
Endosomal Lumen Acidification
System Development
Retinal Cell Programmed Cell Death
Platelet Activation
Regulation Of Transcription, DNA-templated
Regulation Of Metabolic Process
Intracellular Receptor Signaling Pathway
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Collateral Sprouting
Axon Midline Choice Point Recognition
Regulation Of RNA Metabolic Process
RNA Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Necroptotic Signaling Pathway
Response To Organic Substance
Multicellular Organismal Development
Axon Choice Point Recognition
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Response To Abiotic Stimulus
Mullerian Duct Regression
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Gene Expression
Anatomical Structure Development
Regulation Of Nitrogen Compound Metabolic Process
Cellular Chloride Ion Homeostasis
Inflammatory Cell Apoptotic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Proteolysis
Neuron Remodeling
Chloride Ion Homeostasis
Regulation Of Signal Transduction
Tagcloud
?
annealed
boxes
ccnd2
chimpanzee
facts
foxa2
foxc2
gli
gli1
gpcr
gspcr
hedgehog
hes
hey
integrative
jag2
orthologs
overlapping
rtk
runx2
sense
sfrp1
slug
smad
smoothened
snail
tgfbeta
thymus
tss
Tagcloud (Difference)
?
annealed
boxes
ccnd2
chimpanzee
facts
foxa2
foxc2
gli
gli1
gpcr
gspcr
hedgehog
hes
hey
integrative
jag2
orthologs
overlapping
rtk
runx2
sense
sfrp1
slug
smad
smoothened
snail
tgfbeta
thymus
tss
Tagcloud (Intersection)
?