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ITSN2 and EPS8
Number of citations of the paper that reports this interaction (PubMedID
22449706
)
0
Data Source:
BioGRID
(affinity chromatography technology, pull down)
ITSN2
EPS8
Description
intersectin 2
EGFR pathway substrate 8, signaling adaptor
Image
GO Annotations
Cellular Component
Cytoplasm
Centrosome
Cytosol
Plasma Membrane
Presynaptic Membrane
Extracellular Exosome
Intracellular Vesicle
Cytoplasm
Plasma Membrane
Brush Border
Cell Cortex
Postsynaptic Density
Membrane
NMDA Selective Glutamate Receptor Complex
Growth Cone
Vesicle
Stereocilium
Stereocilium Bundle
Stereocilium Tip
Ruffle Membrane
Cell Projection
Neuron Projection
Synapse
Extracellular Exosome
Glutamatergic Synapse
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Protein-macromolecule Adaptor Activity
Metal Ion Binding
Actin Binding
Protein Binding
Small GTPase Binding
Biological Process
Endocytosis
Endosomal Transport
Cell Differentiation
Clathrin-dependent Synaptic Vesicle Endocytosis
Positive Regulation Of Dendrite Extension
Rho Protein Signal Transduction
Adult Locomotory Behavior
Regulation Of Cell Shape
Exit From Mitosis
Rac Protein Signal Transduction
Actin Cytoskeleton Organization
Regulation Of Actin Filament Length
Regulation Of Rho Protein Signal Transduction
Dendritic Cell Migration
Behavioral Response To Ethanol
Barbed-end Actin Filament Capping
Actin Filament Bundle Assembly
Actin Crosslink Formation
Actin Polymerization-dependent Cell Motility
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Positive Regulation Of Ruffle Assembly
Cellular Response To Leukemia Inhibitory Factor
Pathways
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
RHOU GTPase cycle
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS
Appendicular lean mass (
33097823
)
Asthma (
29273806
)
Chromium levels (
26025379
)
Diffuse large B cell lymphoma (
25261932
)
Feeling fed-up (
29500382
)
Low density lipoprotein cholesterol levels (
32154731
33339817
)
Lung cancer (
28604730
)
Lung cancer in ever smokers (
28604730
)
Response to antipsychotic treatment in schizophrenia (working memory) (
21107309
)
Sjögren's syndrome (
24097067
)
Total cholesterol levels (
33339817
)
Metabolite levels (
23823483
)
Protein quantitative trait loci (
18464913
)
Interacting Genes
74 interacting genes:
AGT
AHDC1
AMPH
ANKRD17
BCCIP
CBL
CCDC88C
CHIC2
CPSF6
DLGAP1
DST
EGFR
EPS8
ERC1
FASLG
FCHSD1
FCHSD2
FNBP4
GAREM2
GOLGA2
GOLGA8A
GOLGB1
GPNMB
HNRNPK
HOOK2
ITPKA
ITSN1
KCTD10
KDM1A
KHDRBS1
KIAA1549
KXD1
LSM8
LTBP4
LUC7L3
MAP4K3
MBNL1
MEGF10
NBR1
NR2C2
PDCD6IP
PDE4DIP
PIK3AP1
PIK3C2B
PSEN1
PTN
RAD9A
RBMX
REPS1
RNF20
ROCK1
RUFY1
SEMA6A
SH3GL1
SH3KBP1
SNAP29
SNCA
SOS1
SOS2
STX4
SYN1
SYNJ2
TACC1
TBL3
TMF1
TRIO
UBC
WAS
WASF2
WASL
WIPF1
WIPF2
YLPM1
YTHDF1
61 interacting genes:
ABI1
ACTA1
ADAM22
AIMP2
ALDH7A1
ARMC1
BAIAP2
BCKDK
BLOC1S6
BORCS6
BYSL
C19orf25
C6orf141
C8orf33
CASK
CBL
CCDC85B
CSNK2B
CTNNA3
CXCL2
DNALI1
DVL1
EGFR
GOLGA8EP
GRB2
GULP1
HNRNPC
HOOK2
INPP5J
ITGB1
ITGB3
ITGB5
ITSN2
MAP1LC3B
MAP3K11
MRPL20
MYO15A
NACC2
NFKB2
PCM1
PROSER2
RCAN3
RFXAP
RSPH14
RUNX1T1
SCRN3
SERPINA5
SF3B3
SHB
SHC1
SLC27A4
SMARCE1
SOS1
SRC
TDP2
TEX28
TPRN
USP6NL
XAGE2
XRCC6
ZZZ3
Entrez ID
50618
2059
HPRD ID
09193
02563
Ensembl ID
ENSG00000198399
ENSG00000151491
Uniprot IDs
A6H8W8
Q9NZM3
B4E3T6
Q12929
PDB IDs
1J3T
1UDL
1UE9
1UFF
1UHF
3GF9
3JZY
4IIO
2E8M
7TZK
Enriched GO Terms of Interacting Partners
?
SH3 Domain Binding
Endocytosis
Cell Projection
Vesicle-mediated Transport
Actin Filament-based Movement
Import Into Cell
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Establishment Of Localization In Cell
Cytoskeleton
Positive Regulation Of Cellular Component Organization
Regulation Of Supramolecular Fiber Organization
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of ERBB Signaling Pathway
Cytoplasmic Vesicle
Cytoskeleton Organization
Small GTPase-mediated Signal Transduction
Cytoplasm
Synaptic Vesicle Endocytosis
Organelle Localization
Glutamatergic Synapse
Presynaptic Endocytosis
Actin Binding
Vesicle-mediated Transport In Synapse
Organelle Organization
Supramolecular Fiber Organization
Cadherin Binding
Actin Filament-based Process
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Cell Communication
Regulation Of Signaling
Cellular Localization
Regulation Of Cellular Component Organization
Regulation Of Cytoskeleton Organization
Membrane Organization
MRNA Binding
Protein Complex Oligomerization
Regulation Of Vesicle-mediated Transport
Regulation Of Angiotensin-activated Signaling Pathway
Intracellular Transport
Apical Constriction
Positive Regulation Of RNA Export From Nucleus
Cellular Component Assembly
Cytosol
Actin Cytoskeleton
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of Synaptic Plasticity
Cell-cell Signaling
Regulation Of Intracellular Signal Transduction
Modulation Of Chemical Synaptic Transmission
Epidermal Growth Factor Receptor Signaling Pathway
Filopodium
ERBB Signaling Pathway
Protein Tyrosine Kinase Activator Activity
Supramolecular Fiber Organization
Actin Filament Organization
Symbiont Entry Into Host Cell
Ephrin Receptor Binding
Actin Filament Bundle Organization
Actin Filament Bundle Assembly
Shc-EGFR Complex
Focal Adhesion
Enzyme-linked Receptor Protein Signaling Pathway
Wound Healing, Spreading Of Epidermal Cells
Phosphotyrosine Residue Binding
Biological Process Involved In Interaction With Host
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Developmental Process
Schwann Cell Development
Ruffle
SH3 Domain Binding
Cellular Response To Growth Factor Stimulus
Cellular Response To Platelet-derived Growth Factor Stimulus
Epidermal Growth Factor Binding
ERBB2 Signaling Pathway
Contractile Actin Filament Bundle Assembly
Stress Fiber Assembly
Response To Platelet-derived Growth Factor
Neuregulin Binding
Integrin Complex
C-X3-C Chemokine Binding
Cell Adhesion Mediated By Integrin
Response To Growth Factor
Wound Healing, Spreading Of Cells
Response To Activity
Neurotrophin TRKA Receptor Binding
Endocytosis
Insulin Receptor Signaling Pathway
Integrin Binding
Virus Receptor Activity
Insulin-like Growth Factor Receptor Signaling Pathway
Epidermal Growth Factor Receptor Binding
Heterotypic Cell-cell Adhesion
Actin-based Cell Projection
Cellular Developmental Process
Import Into Cell
Schaffer Collateral - CA1 Synapse
Ruffle Membrane
Integrin-mediated Signaling Pathway
Lamellipodium
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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