ITSN2 and FNBP4

Number of citations of the paper that reports this interaction (PMID 22558309)
5

Data Source:
BioGRID (two hybrid)

		ITSN2	FNBP4
Gene Name		intersectin 2	formin binding protein 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Nucleoplasm
	Molecular Function	SH3/SH2 Adaptor Activity Rho Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	Protein Binding
	Biological Process	Endocytosis Positive Regulation Of Signal Transduction Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS		Working memory ( 21107309)
Protein-Protein Interactions		75 interactors: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EPS15 EPS15L1 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREML GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	10 interactors: CSNK2A1 FYN ITSN1 ITSN2 KHDRBS1 LBR PLXNA2 PRPF40A SNRPB SYNJ1
Entrez ID		50618	23360
HPRD ID		09193	10996
Ensembl ID		ENSG00000198399	ENSG00000109920
Uniprot IDs		A6H8W8 Q9NZM3	B3KNP0 Q8N3X1
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cell Communication Signaling Cellular Response To Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cellular Component Assembly Signal Transduction Synaptic Vesicle Transport Enzyme Linked Receptor Protein Signaling Pathway Actin Filament-based Movement Cell-cell Signaling Response To Stimulus Establishment Of Vesicle Localization Cell Surface Receptor Signaling Pathway Vesicle Localization Organelle Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cellular Process Negative Regulation Of Membrane Tubulation Regulation Of Signaling Protein Complex Assembly Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Vesicle Organization Establishment Of Organelle Localization Positive Regulation Of Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Immune Response-regulating Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Positive Regulation Of Cell Death Transport Apoptotic Process Cellular Localization Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Differentiation Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Establishment Of Localization In Cell Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway	Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Locomotion Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Synaptic Vesicle Endocytosis Synaptic Vesicle Recycling Endocytosis Cell Morphogenesis Involved In Differentiation Movement Of Cell Or Subcellular Component Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Cerebellar Granule Cell Precursor Tangential Migration Positive Regulation Of Synaptic Vesicle Uncoating Synaptic Vesicle Uncoating Regulation Of Synaptic Vesicle Membrane Organization Organelle Localization Regulation Of Signaling MRNA Processing Cell Morphogenesis Ephrin Receptor Signaling Pathway Neuron Differentiation Hindbrain Tangential Cell Migration Positive Regulation Of RNA Export From Nucleus Cell Projection Organization Synaptic Vesicle Transport Negative Regulation Of Protein Catabolic Process MRNA Metabolic Process Positive Regulation Of Synaptic Vesicle Endocytosis RNA Processing Learning Regulation Of Cell Shape Vesicle-mediated Transport Negative Regulation Of Neuron Apoptotic Process Regulation Of Synaptic Vesicle Endocytosis Generation Of Neurons Negative Regulation Of Neuron Death Establishment Of Vesicle Localization Regulation Of Signal Transduction Regulation Of Synaptic Vesicle Recycling Synaptic Vesicle Priming Vesicle Localization Neurogenesis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway
Tagcloud ?		abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates	athanogene bag3 bcl2 cancerous developmentally e3 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Difference) ?		abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates	athanogene bag3 bcl2 cancerous developmentally e3 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a sgsm3 tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Intersection) ?