EPS8 and SLC27A4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EPS8	SLC27A4
Gene Name		epidermal growth factor receptor pathway substrate 8	solute carrier family 27 (fatty acid transporter), member 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cell Cortex Postsynaptic Density N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Growth Cone Vesicle Stereocilium Ruffle Membrane Extracellular Vesicular Exosome	Endoplasmic Reticulum Membrane Plasma Membrane Microvillus Membrane Integral Component Of Membrane Brush Border Membrane
	Molecular Function	Actin Binding SH3/SH2 Adaptor Activity Protein Binding Rac GTPase Binding	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity Fatty Acid Transporter Activity Very Long-chain Fatty Acid-CoA Ligase Activity
	Biological Process	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell Proliferation Adult Locomotory Behavior Regulation Of Cell Shape Positive Regulation Of Signal Transduction Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Actin Cytoskeleton Reorganization Dendritic Cell Migration Behavioral Response To Ethanol Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility	Medium-chain Fatty Acid Transport Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Transport Response To Nutrient Fatty Acid Transport Long-chain Fatty Acid Transport Very Long-chain Fatty Acid Catabolic Process Skin Development Long-chain Fatty Acid Import Transmembrane Transport
Pathways			Transport of vitamins, nucleosides, and related molecules SLC-mediated transmembrane transport Transport of fatty acids
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		54 interactors: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BYSL C17orf59 C19orf25 C8orf33 CASK CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RFXAP RUNX1T1 SCRN3 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XRCC6 ZZZ3	1 interactors: EPS8
Entrez ID		2059	10999
HPRD ID		02563	09172
Ensembl ID		ENSG00000151491	ENSG00000167114
Uniprot IDs		B4DX66 B4E3T6 Q12929	Q6P1M0
PDB IDs		2E8M
Enriched GO Terms of Interacting Partners?		Cell Differentiation Developmental Process Movement Of Cell Or Subcellular Component Multicellular Organismal Development System Development Anatomical Structure Development Cell Projection Morphogenesis Cell Part Morphogenesis Axonogenesis Axon Guidance Fc Receptor Signaling Pathway Axon Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Chemotaxis Neurogenesis Neuron Projection Development Immune Response-regulating Signaling Pathway Neuron Projection Morphogenesis Organelle Organization Positive Regulation Of Signal Transduction Cell Morphogenesis Leukocyte Migration Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Generation Of Neurons Cell Development Response To External Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Development Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Blood Coagulation Fibroblast Growth Factor Receptor Signaling Pathway Hemostasis Regulation Of ERBB Signaling Pathway Nervous System Development Innate Immune Response Anatomical Structure Formation Involved In Morphogenesis Regulation Of Protein Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Phosphorylation Regulation Of Immune System Process Platelet Activation Response To Fibroblast Growth Factor	Actin Polymerization-dependent Cell Motility Exit From Mitosis Behavioral Response To Ethanol Rac Protein Signal Transduction Actin Crosslink Formation Barbed-end Actin Filament Capping Dendritic Cell Migration Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Actin Cytoskeleton Reorganization Actin Filament Bundle Assembly Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Polymerization Negative Regulation Of Protein Complex Disassembly Regulation Of Protein Depolymerization Adult Locomotory Behavior Regulation Of Protein Complex Disassembly Negative Regulation Of Protein Complex Assembly Response To Ethanol Negative Regulation Of Cytoskeleton Organization Regulation Of Cell Shape Epidermal Growth Factor Receptor Signaling Pathway Adult Behavior ERBB Signaling Pathway Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Ras Protein Signal Transduction Leukocyte Migration Locomotory Behavior Actin Filament Organization Mitotic Nuclear Division Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Single-organism Behavior Regulation Of Cell Morphogenesis Regulation Of Cytoskeleton Organization Behavior Actin Cytoskeleton Organization Small GTPase Mediated Signal Transduction Actin Filament-based Process
Tagcloud ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound
Tagcloud (Difference) ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound
Tagcloud (Intersection) ?