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EPS8 and C19orf25
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
EPS8
C19orf25
Description
EGFR pathway substrate 8, signaling adaptor
chromosome 19 open reading frame 25
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Brush Border
Cell Cortex
Postsynaptic Density
Membrane
NMDA Selective Glutamate Receptor Complex
Growth Cone
Vesicle
Stereocilium
Stereocilium Bundle
Stereocilium Tip
Ruffle Membrane
Cell Projection
Neuron Projection
Synapse
Extracellular Exosome
Glutamatergic Synapse
Molecular Function
Actin Binding
Protein Binding
Small GTPase Binding
Protein Binding
Biological Process
Rho Protein Signal Transduction
Adult Locomotory Behavior
Regulation Of Cell Shape
Exit From Mitosis
Rac Protein Signal Transduction
Actin Cytoskeleton Organization
Regulation Of Actin Filament Length
Regulation Of Rho Protein Signal Transduction
Dendritic Cell Migration
Behavioral Response To Ethanol
Barbed-end Actin Filament Capping
Actin Filament Bundle Assembly
Actin Crosslink Formation
Actin Polymerization-dependent Cell Motility
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Positive Regulation Of Ruffle Assembly
Cellular Response To Leukemia Inhibitory Factor
Pathways
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Protein quantitative trait loci (
18464913
)
Lean body mass (
28552196
)
Waist circumference adjusted for body mass index (
28552196
)
Interacting Genes
61 interacting genes:
ABI1
ACTA1
ADAM22
AIMP2
ALDH7A1
ARMC1
BAIAP2
BCKDK
BLOC1S6
BORCS6
BYSL
C19orf25
C6orf141
C8orf33
CASK
CBL
CCDC85B
CSNK2B
CTNNA3
CXCL2
DNALI1
DVL1
EGFR
GOLGA8EP
GRB2
GULP1
HNRNPC
HOOK2
INPP5J
ITGB1
ITGB3
ITGB5
ITSN2
MAP1LC3B
MAP3K11
MRPL20
MYO15A
NACC2
NFKB2
PCM1
PROSER2
RCAN3
RFXAP
RSPH14
RUNX1T1
SCRN3
SERPINA5
SF3B3
SHB
SHC1
SLC27A4
SMARCE1
SOS1
SRC
TDP2
TEX28
TPRN
USP6NL
XAGE2
XRCC6
ZZZ3
19 interacting genes:
ARFIP2
BAIAP2
BORCS6
BRME1
CCDC85B
CEP170P1
CRX
DDIT4L
DRC12
EPS8
INSYN1
KRT75
KRTAP1-3
KRTAP10-8
MEI4
NECAB2
PNMA3
SAT1
TFPT
Entrez ID
2059
148223
HPRD ID
02563
12703
Ensembl ID
ENSG00000151491
ENSG00000119559
Uniprot IDs
B4E3T6
Q12929
Q9UFG5
PDB IDs
2E8M
7TZK
Enriched GO Terms of Interacting Partners
?
Epidermal Growth Factor Receptor Signaling Pathway
Filopodium
ERBB Signaling Pathway
Protein Tyrosine Kinase Activator Activity
Supramolecular Fiber Organization
Actin Filament Organization
Symbiont Entry Into Host Cell
Ephrin Receptor Binding
Actin Filament Bundle Organization
Actin Filament Bundle Assembly
Shc-EGFR Complex
Focal Adhesion
Enzyme-linked Receptor Protein Signaling Pathway
Wound Healing, Spreading Of Epidermal Cells
Phosphotyrosine Residue Binding
Biological Process Involved In Interaction With Host
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Developmental Process
Schwann Cell Development
Ruffle
SH3 Domain Binding
Cellular Response To Growth Factor Stimulus
Cellular Response To Platelet-derived Growth Factor Stimulus
Epidermal Growth Factor Binding
ERBB2 Signaling Pathway
Contractile Actin Filament Bundle Assembly
Stress Fiber Assembly
Response To Platelet-derived Growth Factor
Neuregulin Binding
Integrin Complex
C-X3-C Chemokine Binding
Cell Adhesion Mediated By Integrin
Response To Growth Factor
Wound Healing, Spreading Of Cells
Response To Activity
Neurotrophin TRKA Receptor Binding
Endocytosis
Insulin Receptor Signaling Pathway
Integrin Binding
Virus Receptor Activity
Insulin-like Growth Factor Receptor Signaling Pathway
Epidermal Growth Factor Receptor Binding
Heterotypic Cell-cell Adhesion
Actin-based Cell Projection
Cellular Developmental Process
Import Into Cell
Schaffer Collateral - CA1 Synapse
Ruffle Membrane
Integrin-mediated Signaling Pathway
Lamellipodium
Actin Crosslink Formation
Keratin Filament
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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