ITSN2 and TMF1

Number of citations of the paper that reports this interaction (PubMedID 22558309)
58

Data Source:
BioGRID (two hybrid)

		ITSN2	TMF1
Description		intersectin 2	TATA element modulatory factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Plasma Membrane Presynaptic Membrane Extracellular Exosome Intracellular Vesicle	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Metal Ion Binding	DNA Binding Transcription Coactivator Activity Protein Binding Nuclear Androgen Receptor Binding
	Biological Process	Endocytosis Endosomal Transport Cell Differentiation Clathrin-dependent Synaptic Vesicle Endocytosis Positive Regulation Of Dendrite Extension	Acrosome Assembly Positive Regulation Of Cytokine Production Apoptotic Process Spermatid Development Spermatid Nucleus Differentiation Male Gonad Development Negative Regulation Of Gene Expression Flagellated Sperm Motility Androgen Receptor Signaling Pathway Luteinizing Hormone Secretion Leydig Cell Differentiation Defense Response To Bacterium Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Proteasomal Protein Catabolic Process Epithelial Cell Apoptotic Process Negative Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Testosterone Secretion
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis RHOU GTPase cycle	Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Asthma ( 29273806) Chromium levels ( 26025379) Diffuse large B cell lymphoma ( 25261932) Feeling fed-up ( 29500382) Low density lipoprotein cholesterol levels ( 32154731 33339817) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309) Sjögren's syndrome ( 24097067) Total cholesterol levels ( 33339817)	Meat-related diet ( 32066663) Metabolite levels ( 23823483)
Interacting Genes		74 interacting genes: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DST EGFR EPS8 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREM2 GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SNCA SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO UBC WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	9 interacting genes: AR CMTM5 FER GFI1B ITSN2 KAT2B NR3C1 RAB6A SMARCA4
Entrez ID		50618	7110
HPRD ID		09193	03081
Ensembl ID		ENSG00000198399	ENSG00000144747
Uniprot IDs		A6H8W8 Q9NZM3	P82094 Q6PII6
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY 4IIO
Enriched GO Terms of Interacting Partners?		SH3 Domain Binding Endocytosis Cell Projection Vesicle-mediated Transport Actin Filament-based Movement Import Into Cell Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Establishment Of Localization In Cell Cytoskeleton Positive Regulation Of Cellular Component Organization Regulation Of Supramolecular Fiber Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Cytoplasmic Vesicle Cytoskeleton Organization Small GTPase-mediated Signal Transduction Cytoplasm Synaptic Vesicle Endocytosis Organelle Localization Glutamatergic Synapse Presynaptic Endocytosis Actin Binding Vesicle-mediated Transport In Synapse Organelle Organization Supramolecular Fiber Organization Cadherin Binding Actin Filament-based Process Positive Regulation Of Cellular Component Biogenesis Regulation Of Cell Communication Regulation Of Signaling Cellular Localization Regulation Of Cellular Component Organization Regulation Of Cytoskeleton Organization Membrane Organization MRNA Binding Protein Complex Oligomerization Regulation Of Vesicle-mediated Transport Regulation Of Angiotensin-activated Signaling Pathway Intracellular Transport Apical Constriction Positive Regulation Of RNA Export From Nucleus Cellular Component Assembly Cytosol Actin Cytoskeleton Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Synaptic Plasticity Cell-cell Signaling Regulation Of Intracellular Signal Transduction Modulation Of Chemical Synaptic Transmission	Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Estrogen Response Element Binding Protein-containing Complex Seminiferous Tubule Development Negative Regulation Of Transcription By RNA Polymerase II Steroid Binding Chromatin Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Nuclear Receptor Activity Regulation Of Gluconeogenesis Positive Regulation Of Gene Expression, Epigenetic Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of Nucleobase-containing Compound Metabolic Process Prostate Induction Lipid Binding Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Cellular Response To Oxygen-containing Compound RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Male Somatic Sex Determination Cellular Response To Hormone Stimulus Regulation Of Developmental Process Adherens Junction Disassembly Nuclear Glucocorticoid Receptor Activity Chromatin Organization Peptidyl-cysteine Methylation Regulation Of Myoblast Differentiation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cellular Response To Steroid Hormone Stimulus Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis Cell-cell Junction Disassembly Negative Regulation Of RRNA Processing Histone H3K9 Acetyltransferase Activity Clathrin-dependent Synaptic Vesicle Endocytosis DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Regulation Of Glucose Metabolic Process Nuclear Receptor-mediated Signaling Pathway Male Gonad Development Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Integrin Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?