EPS8 and GULP1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EPS8	GULP1
Gene Name		epidermal growth factor receptor pathway substrate 8	GULP, engulfment adaptor PTB domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cell Cortex Postsynaptic Density N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Growth Cone Vesicle Stereocilium Ruffle Membrane Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	Actin Binding SH3/SH2 Adaptor Activity Protein Binding Rac GTPase Binding	Signal Transducer Activity
	Biological Process	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell Proliferation Adult Locomotory Behavior Regulation Of Cell Shape Positive Regulation Of Signal Transduction Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Actin Cytoskeleton Reorganization Dendritic Cell Migration Behavioral Response To Ethanol Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility	Lipid Transport Phagocytosis, Engulfment Apoptotic Process Signal Transduction
Pathways
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		54 interactors: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BYSL C17orf59 C19orf25 C8orf33 CASK CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RFXAP RUNX1T1 SCRN3 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XRCC6 ZZZ3	4 interactors: CREB3L2 EPS8 LRP1 SMC2
Entrez ID		2059	51454
HPRD ID		02563	12181
Ensembl ID		ENSG00000151491
Uniprot IDs		B4DX66 B4E3T6 Q12929	Q9UBP9
PDB IDs		2E8M
Enriched GO Terms of Interacting Partners?		Cell Differentiation Developmental Process Movement Of Cell Or Subcellular Component Multicellular Organismal Development System Development Anatomical Structure Development Cell Projection Morphogenesis Cell Part Morphogenesis Axonogenesis Axon Guidance Fc Receptor Signaling Pathway Axon Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Chemotaxis Neurogenesis Neuron Projection Development Immune Response-regulating Signaling Pathway Neuron Projection Morphogenesis Organelle Organization Positive Regulation Of Signal Transduction Cell Morphogenesis Leukocyte Migration Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Generation Of Neurons Cell Development Response To External Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Development Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Blood Coagulation Fibroblast Growth Factor Receptor Signaling Pathway Hemostasis Regulation Of ERBB Signaling Pathway Nervous System Development Innate Immune Response Anatomical Structure Formation Involved In Morphogenesis Regulation Of Protein Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Phosphorylation Regulation Of Immune System Process Platelet Activation Response To Fibroblast Growth Factor	Beta-amyloid Clearance Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Actin Polymerization-dependent Cell Motility Mitotic Nuclear Division Exit From Mitosis Regulation Of Actin Cytoskeleton Organization Behavioral Response To Ethanol Meiotic Chromosome Condensation Regulation Of Actin Filament-based Process Regulation Of Phospholipase A2 Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Cytoskeleton Organization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Rac Protein Signal Transduction Negative Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Cholesterol Efflux Lipoprotein Transport Positive Regulation Of Cholesterol Transport Barbed-end Actin Filament Capping Actin Crosslink Formation Dendritic Cell Migration Regulation Of Cholesterol Efflux Aorta Morphogenesis Mitotic Chromosome Condensation Mitotic Cell Cycle Process Aorta Development Kinetochore Organization Cell Proliferation Apoptotic Cell Clearance Mitotic Cell Cycle Regulation Of Cholesterol Transport Regulation Of Smooth Muscle Cell Migration
Tagcloud ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound	adaptor adaptors additionally another app binds characterize differential engulfment fe65 functionally influencing intracellular lipoprotein lrp1 mediate mediates motifs npxy phosphotyrosine plasmid precursor ptb reporter signalling supported thereby trafficking transactivation
Tagcloud (Difference) ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound	adaptor adaptors additionally another app binds characterize differential engulfment fe65 functionally influencing intracellular lipoprotein lrp1 mediate mediates motifs npxy phosphotyrosine plasmid precursor ptb reporter signalling supported thereby trafficking transactivation
Tagcloud (Intersection) ?