ITSN2 and YLPM1

Number of citations of the paper that reports this interaction (PMID 22558309)
5

Data Source:
BioGRID (two hybrid)

		ITSN2	YLPM1
Gene Name		intersectin 2	YLP motif containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	SH3/SH2 Adaptor Activity Rho Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Poly(A) RNA Binding
	Biological Process	Endocytosis Positive Regulation Of Signal Transduction Positive Regulation Of Rho GTPase Activity	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Biological_process Regulation Of Telomere Maintenance
Pathways
Drugs
Diseases
GWAS		Working memory ( 21107309)
Protein-Protein Interactions		75 interactors: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EPS15 EPS15L1 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREML GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	11 interactors: APBB1 BMP1 CACNA1A CHGB GRB2 ITSN2 NONO PPP1CA PPP1CC PRMT1 PRPF40A
Entrez ID		50618	56252
HPRD ID		09193	11688
Ensembl ID		ENSG00000198399	ENSG00000119596
Uniprot IDs		A6H8W8 Q9NZM3	P49750 Q8NF45
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cell Communication Signaling Cellular Response To Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cellular Component Assembly Signal Transduction Synaptic Vesicle Transport Enzyme Linked Receptor Protein Signaling Pathway Actin Filament-based Movement Cell-cell Signaling Response To Stimulus Establishment Of Vesicle Localization Cell Surface Receptor Signaling Pathway Vesicle Localization Organelle Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cellular Process Negative Regulation Of Membrane Tubulation Regulation Of Signaling Protein Complex Assembly Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Vesicle Organization Establishment Of Organelle Localization Positive Regulation Of Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Immune Response-regulating Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Positive Regulation Of Cell Death Transport Apoptotic Process Cellular Localization Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Differentiation Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Establishment Of Localization In Cell Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway	Regulation Of Circadian Rhythm Energy Reserve Metabolic Process Response To Radiation Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Circadian Rhythm Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Energy Derivation By Oxidation Of Organic Compounds Rhythmic Process Neuron Projection Development Glycogen Metabolic Process Response To Light Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cerebellar Molecular Layer Development Negative Regulation Of Thymidylate Synthase Biosynthetic Process Neuron Development Response To External Stimulus Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Generation Of Precursor Metabolites And Energy Cell Division Regulation Of Signaling Triglyceride Metabolic Process Negative Regulation Of Signal Transduction Response To Abiotic Stimulus Neuron Differentiation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Vestibular Nucleus Development Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Projection Organization Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Signaling Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Transforming Growth Factor Beta Receptor Signaling Pathway Cell Cycle Gamma-aminobutyric Acid Secretion Response To Growth Factor Cellular Lipid Catabolic Process Anatomical Structure Morphogenesis Neuron Projection Morphogenesis Negative Regulation Of Megakaryocyte Differentiation Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Acetylcholine Secretion, Neurotransmission Regulation Of Apoptotic Process
Tagcloud ?		abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates
Tagcloud (Difference) ?		abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates
Tagcloud (Intersection) ?