EPS8 and BAIAP2

Number of citations of the paper that reports this interaction (PMID 15289329)
21

Data Source:
HPRD (in vivo)

		EPS8	BAIAP2
Gene Name		epidermal growth factor receptor pathway substrate 8	BAI1-associated protein 2
Image
Gene Ontology Annotations	Cellular Component	Cell Cortex Postsynaptic Density N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Growth Cone Vesicle Stereocilium Ruffle Membrane Extracellular Vesicular Exosome	Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Filopodium Neuron Projection Extracellular Vesicular Exosome
	Molecular Function	Actin Binding SH3/SH2 Adaptor Activity Protein Binding Rac GTPase Binding	Protein Binding Protein C-terminus Binding Cytoskeletal Adaptor Activity Identical Protein Binding Proline-rich Region Binding
	Biological Process	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell Proliferation Adult Locomotory Behavior Regulation Of Cell Shape Positive Regulation Of Signal Transduction Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Actin Cytoskeleton Reorganization Dendritic Cell Migration Behavioral Response To Ethanol Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility	Plasma Membrane Organization Axonogenesis Insulin Receptor Signaling Pathway Regulation Of Cell Shape Response To Bacterium Dendrite Development Regulation Of Actin Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Synaptic Plasticity Actin Filament Bundle Assembly Actin Crosslink Formation
Pathways			Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		54 interactors: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BYSL C17orf59 C19orf25 C8orf33 CASK CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RFXAP RUNX1T1 SCRN3 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XRCC6 ZZZ3	32 interactors: APP ATN1 BAI1 C14orf1 C19orf25 CDC42 DIAPH1 ENAH EPS8 ESPN KANK1 KDM1A LIN7A LIN7B LIN7C MARK2 NCKIPSD NEDD4 PAK1 PBX2 PRR13 RAC1 RTN4 SF3B4 SHANK1 SHANK2 SRPK2 TP53BP2 WASF1 WASF2 WASL YWHAG
Entrez ID		2059	10458
HPRD ID		02563	05686
Ensembl ID		ENSG00000151491	ENSG00000175866
Uniprot IDs		B4DX66 B4E3T6 Q12929	B4DWA1 I3L4C2 Q9UQB8
PDB IDs		2E8M	1WDZ 1Y2O 2YKT 3RNJ
Enriched GO Terms of Interacting Partners?		Cell Differentiation Developmental Process Movement Of Cell Or Subcellular Component Multicellular Organismal Development System Development Anatomical Structure Development Cell Projection Morphogenesis Cell Part Morphogenesis Axonogenesis Axon Guidance Fc Receptor Signaling Pathway Axon Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Chemotaxis Neurogenesis Neuron Projection Development Immune Response-regulating Signaling Pathway Neuron Projection Morphogenesis Organelle Organization Positive Regulation Of Signal Transduction Cell Morphogenesis Leukocyte Migration Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Generation Of Neurons Cell Development Response To External Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Development Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Blood Coagulation Fibroblast Growth Factor Receptor Signaling Pathway Hemostasis Regulation Of ERBB Signaling Pathway Nervous System Development Innate Immune Response Anatomical Structure Formation Involved In Morphogenesis Regulation Of Protein Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Phosphorylation Regulation Of Immune System Process Platelet Activation Response To Fibroblast Growth Factor	Regulation Of Cytoskeleton Organization Nervous System Development Regulation Of Organelle Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Anatomical Structure Development Regulation Of Cellular Component Organization Regulation Of Cell Projection Organization System Development Multicellular Organismal Development Maintenance Of Cell Polarity Generation Of Neurons Actin Cytoskeleton Organization Developmental Process Neuron Projection Development Actin Filament Organization Actin Filament-based Process Neurogenesis Cytoskeleton Organization Cell Projection Organization Regulation Of Cell Projection Assembly Regulation Of Actin Cytoskeleton Organization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuron Development Protein Localization To Basolateral Plasma Membrane Locomotion Regulation Of Actin Filament-based Process Maintenance Of Epithelial Cell Apical/basal Polarity Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cellular Protein Localization Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cell Projection Organization Maintenance Of Apical/basal Cell Polarity Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Localization Actin Polymerization Or Depolymerization Neuron Differentiation Regulation Of Cell Morphogenesis Establishment Or Maintenance Of Cell Polarity Cell Differentiation Cell Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Signaling Cellular Component Assembly Cell Communication Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Development Cell Morphogenesis
Tagcloud ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound
Tagcloud (Difference) ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound
Tagcloud (Intersection) ?