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ITSN2 and FCHSD2
Number of citations of the paper that reports this interaction (PMID
22558309
)
5
Data Source:
BioGRID
(two hybrid)
ITSN2
FCHSD2
Gene Name
intersectin 2
FCH and double SH3 domains 2
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
SH3/SH2 Adaptor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Protein Binding
Biological Process
Endocytosis
Positive Regulation Of Signal Transduction
Positive Regulation Of Rho GTPase Activity
Pathways
Drugs
Diseases
GWAS
Working memory (
21107309
)
Crohn's disease (
23266558
)
Protein-Protein Interactions
75 interactors:
AGT
AHDC1
AMPH
ANKRD17
BCCIP
CBL
CCDC88C
CHIC2
CPSF6
DLGAP1
DNM2
DST
EPS15
EPS15L1
ERC1
FASLG
FCHSD1
FCHSD2
FNBP4
GAREML
GOLGA2
GOLGA8A
GOLGB1
GPNMB
HNRNPK
HOOK2
ITPKA
ITSN1
KCTD10
KDM1A
KHDRBS1
KIAA1549
KXD1
LARP6
LSM8
LTBP4
LUC7L3
MAP4K3
MBNL1
MEGF10
NBR1
NR2C2
PDCD6IP
PDE4DIP
PIK3AP1
PIK3C2B
PSEN1
PTN
RABEP1
RAD9A
RBMX
REPS1
RNF20
ROCK1
RUFY1
SEMA6A
SH3GL1
SH3KBP1
SNAP29
SOS1
SOS2
STX4
SYN1
SYNJ2
TACC1
TBL3
TMF1
TRIO
WAS
WASF2
WASL
WIPF1
WIPF2
YLPM1
YTHDF1
25 interactors:
ABCF3
C2orf73
C9orf78
CASK
CCDC158
CCDC85B
CCT2
CFAP36
CHKA
DAPP1
FAM9B
HSP90AB1
HSPA5
HTRA1
ITSN1
ITSN2
KIFC3
MSL1
MTUS2
PDE4DIP
SH3BGR
SRP72
VCPIP1
WAS
WASL
Entrez ID
50618
9873
HPRD ID
09193
13321
Ensembl ID
ENSG00000198399
ENSG00000137478
Uniprot IDs
A6H8W8
Q9NZM3
E9PG19
O94868
PDB IDs
1J3T
1UDL
1UE9
1UFF
1UHF
3GF9
3JZY
2DL5
2DL7
Enriched GO Terms of Interacting Partners
?
Vesicle-mediated Transport
Endocytosis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Cell Communication
Signaling
Cellular Response To Stimulus
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Cellular Component Assembly
Signal Transduction
Synaptic Vesicle Transport
Enzyme Linked Receptor Protein Signaling Pathway
Actin Filament-based Movement
Cell-cell Signaling
Response To Stimulus
Establishment Of Vesicle Localization
Cell Surface Receptor Signaling Pathway
Vesicle Localization
Organelle Localization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cellular Component Organization
Regulation Of Cellular Process
Negative Regulation Of Membrane Tubulation
Regulation Of Signaling
Protein Complex Assembly
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger
Vesicle Organization
Establishment Of Organelle Localization
Positive Regulation Of Apoptotic Process
Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Immune Response-regulating Signaling Pathway
Positive Regulation Of ERBB Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Cell Death
Transport
Apoptotic Process
Cellular Localization
Regulation Of Cell Death
Positive Regulation Of Intracellular Signal Transduction
Organelle Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Differentiation
Regulation Of Vesicle-mediated Transport
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Establishment Of Localization In Cell
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Positive Regulation Of Actin Nucleation
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Endocytosis
Regulation Of Actin Nucleation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Regulation Of Cellular Response To Growth Factor Stimulus
Toxin Transport
Cellular Response To Interleukin-4
Vesicle-mediated Transport
Response To Interleukin-4
Regulation Of Protein Folding In Endoplasmic Reticulum
Protein Complex Assembly
Phagocytosis
Actin Filament-based Movement
Fc Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Golgi Organization
Endoplasmic Reticulum Membrane Fusion
Negative Regulation Of Membrane Tubulation
Cerebellum Structural Organization
Transport
Actin Polymerization Or Depolymerization
Cellular Protein Complex Assembly
Zonula Adherens Maintenance
Vesicle Transport Along Actin Filament
Cellular Component Assembly
Ephrin Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Golgi Reassembly
Dentinogenesis
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Axon Guidance
Protein Localization To Endoplasmic Reticulum
Positive Regulation Of Clathrin-mediated Endocytosis
Movement Of Cell Or Subcellular Component
Response To Unfolded Protein
Immune Response-regulating Signaling Pathway
Choline Metabolic Process
Golgi Inheritance
Protein K11-linked Deubiquitination
Tagcloud
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Difference)
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Intersection)
?