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EPS8 and SMARCE1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
EPS8
SMARCE1
Description
EGFR pathway substrate 8, signaling adaptor
SWI/SNF related BAF chromatin remodeling complex subunit E1
Image
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Brush Border
Cell Cortex
Postsynaptic Density
Membrane
NMDA Selective Glutamate Receptor Complex
Growth Cone
Vesicle
Stereocilium
Stereocilium Bundle
Stereocilium Tip
Ruffle Membrane
Cell Projection
Neuron Projection
Synapse
Extracellular Exosome
Glutamatergic Synapse
Nuclear Chromosome
Kinetochore
Chromatin
Nucleus
Nucleoplasm
Nuclear Matrix
SWI/SNF Complex
RSC-type Complex
Protein-containing Complex
Brahma Complex
NpBAF Complex
NBAF Complex
BBAF Complex
Molecular Function
Actin Binding
Protein Binding
Small GTPase Binding
DNA Binding
Chromatin Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
N-acetyltransferase Activity
Nuclear Receptor Binding
Nucleosomal DNA Binding
Biological Process
Rho Protein Signal Transduction
Adult Locomotory Behavior
Regulation Of Cell Shape
Exit From Mitosis
Rac Protein Signal Transduction
Actin Cytoskeleton Organization
Regulation Of Actin Filament Length
Regulation Of Rho Protein Signal Transduction
Dendritic Cell Migration
Behavioral Response To Ethanol
Barbed-end Actin Filament Capping
Actin Filament Bundle Assembly
Actin Crosslink Formation
Actin Polymerization-dependent Cell Motility
Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Positive Regulation Of Ruffle Assembly
Cellular Response To Leukemia Inhibitory Factor
Chromatin Organization
Nucleosome Disassembly
Chromatin Remodeling
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Neurogenesis
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Myoblast Differentiation
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of DNA-templated Transcription
Regulation Of G0 To G1 Transition
Positive Regulation Of Stem Cell Population Maintenance
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Double-strand Break Repair
Regulation Of Nucleotide-excision Repair
Pathways
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
RMTs methylate histone arginines
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of MITF-M-dependent genes involved in pigmentation
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Formation of the canonical BAF (cBAF) complex
Formation of the polybromo-BAF (pBAF) complex
Formation of the embryonic stem cell BAF (esBAF) complex
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Metabolite levels (
23823483
)
Protein quantitative trait loci (
18464913
)
Allergic disease (asthma, hay fever and/or eczema) (age of onset) (
32603359
)
Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) (
32603359
)
Allergic disease (asthma, hay fever or eczema) (
29083406
29785011
)
Allergic rhinitis (
31361310
)
Asthma (
30929738
31619474
31959851
)
Asthma (childhood onset) (
30929738
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Eczema (
31361310
)
Triglyceride levels in HIV infection (
33109212
)
Interacting Genes
61 interacting genes:
ABI1
ACTA1
ADAM22
AIMP2
ALDH7A1
ARMC1
BAIAP2
BCKDK
BLOC1S6
BORCS6
BYSL
C19orf25
C6orf141
C8orf33
CASK
CBL
CCDC85B
CSNK2B
CTNNA3
CXCL2
DNALI1
DVL1
EGFR
GOLGA8EP
GRB2
GULP1
HNRNPC
HOOK2
INPP5J
ITGB1
ITGB3
ITGB5
ITSN2
MAP1LC3B
MAP3K11
MRPL20
MYO15A
NACC2
NFKB2
PCM1
PROSER2
RCAN3
RFXAP
RSPH14
RUNX1T1
SCRN3
SERPINA5
SF3B3
SHB
SHC1
SLC27A4
SMARCE1
SOS1
SRC
TDP2
TEX28
TPRN
USP6NL
XAGE2
XRCC6
ZZZ3
94 interacting genes:
AMOTL2
AR
ARID2
BAZ1B
BRAP
BRMS1
CCDC136
CCDC172
CCDC183
CCHCR1
CDR2
CEBPA
CEP170P1
CEP63
CEP70
CYSRT1
DISC1
EPS8
ERG
ESR1
ESR2
EXOC4
EXOC7
FAM217B
FSD2
GATA1
GOLGA2
GOLGA6L9
GRIPAP1
HUNK
IFT74
IFT88
ING5
ITCH
JAKMIP2
KIFC3
KLF1
KRT14
KRT15
KRT16
KRT19
KRT27
KRT31
KRT34
KRT35
KRT37
KRT39
KRT40
KRTAP1-1
KRTAP10-8
KRTAP10-9
KRTAP6-3
MDM2
MED4
MEOX2
MIPOL1
MRFAP1L1
MTUS2
NBPF22P
NCOA1
NCOA2
NCOA3
NOTCH2NLA
NR0B2
NR3C1
NUP62
OGT
OIP5
PGR
PSMC6
RALBP1
RARB
RCOR1
RELB
RINT1
RSPH1
SIN3A
SIN3B
SMAD1
SMARCA4
SPAG5
SRC
STX11
SYCE1
TEX12
TFE3
TFIP11
TIAM1
TNIK
TRIM54
TRIP10
TXLNA
USHBP1
VPS52
Entrez ID
2059
6605
HPRD ID
02563
04382
Ensembl ID
ENSG00000151491
ENSG00000073584
Uniprot IDs
B4E3T6
Q12929
Q969G3
PDB IDs
2E8M
7TZK
6LTH
6LTJ
7CYU
7VDV
7Y8R
Enriched GO Terms of Interacting Partners
?
Epidermal Growth Factor Receptor Signaling Pathway
Filopodium
ERBB Signaling Pathway
Protein Tyrosine Kinase Activator Activity
Supramolecular Fiber Organization
Actin Filament Organization
Symbiont Entry Into Host Cell
Ephrin Receptor Binding
Actin Filament Bundle Organization
Actin Filament Bundle Assembly
Shc-EGFR Complex
Focal Adhesion
Enzyme-linked Receptor Protein Signaling Pathway
Wound Healing, Spreading Of Epidermal Cells
Phosphotyrosine Residue Binding
Biological Process Involved In Interaction With Host
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Developmental Process
Schwann Cell Development
Ruffle
SH3 Domain Binding
Cellular Response To Growth Factor Stimulus
Cellular Response To Platelet-derived Growth Factor Stimulus
Epidermal Growth Factor Binding
ERBB2 Signaling Pathway
Contractile Actin Filament Bundle Assembly
Stress Fiber Assembly
Response To Platelet-derived Growth Factor
Neuregulin Binding
Integrin Complex
C-X3-C Chemokine Binding
Cell Adhesion Mediated By Integrin
Response To Growth Factor
Wound Healing, Spreading Of Cells
Response To Activity
Neurotrophin TRKA Receptor Binding
Endocytosis
Insulin Receptor Signaling Pathway
Integrin Binding
Virus Receptor Activity
Insulin-like Growth Factor Receptor Signaling Pathway
Epidermal Growth Factor Receptor Binding
Heterotypic Cell-cell Adhesion
Actin-based Cell Projection
Cellular Developmental Process
Import Into Cell
Schaffer Collateral - CA1 Synapse
Ruffle Membrane
Integrin-mediated Signaling Pathway
Lamellipodium
Keratin Filament
Intermediate Filament
Structural Constituent Of Skin Epidermis
Intermediate Filament Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Nuclear Receptor-mediated Signaling Pathway
Morphogenesis Of An Epithelium
Cytoskeleton
Tissue Morphogenesis
Estrogen Response Element Binding
Chromatin
Structural Molecule Activity
Protein Binding
Intracellular Receptor Signaling Pathway
Cytoskeleton Organization
Organelle Organization
Hormone-mediated Signaling Pathway
Steroid Hormone Receptor Signaling Pathway
Nuclear Receptor-mediated Steroid Hormone Signaling Pathway
Chromatin Binding
Steroid Binding
Nuclear Receptor Activity
Supramolecular Fiber Organization
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Epithelial Cell Differentiation
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Intracellular Signal Transduction
Anatomical Structure Morphogenesis
Cellular Developmental Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Nuclear Steroid Receptor Activity
Sin3-type Complex
Estrogen Receptor Signaling Pathway
Positive Regulation Of Stem Cell Population Maintenance
Cytosol
Positive Regulation Of RNA Metabolic Process
Epidermis Development
Cell Differentiation
DNA-binding Transcription Factor Activity
Protein-containing Complex
Cellular Response To Hormone Stimulus
Negative Regulation Of Transcription By RNA Polymerase II
Nucleoplasm
Developmental Process
Transcription Repressor Complex
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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