EPS8 and SMARCE1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EPS8	SMARCE1
Gene Name		epidermal growth factor receptor pathway substrate 8	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cell Cortex Postsynaptic Density N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Growth Cone Vesicle Stereocilium Ruffle Membrane Extracellular Vesicular Exosome	Nuclear Chromosome Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Transcriptional Repressor Complex Protein Complex NpBAF Complex NBAF Complex
	Molecular Function	Actin Binding SH3/SH2 Adaptor Activity Protein Binding Rac GTPase Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Ligand-dependent Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding
	Biological Process	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell Proliferation Adult Locomotory Behavior Regulation Of Cell Shape Positive Regulation Of Signal Transduction Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Actin Cytoskeleton Reorganization Dendritic Cell Migration Behavioral Response To Ethanol Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Metabolic Process ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		54 interactors: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BYSL C17orf59 C19orf25 C8orf33 CASK CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RFXAP RUNX1T1 SCRN3 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XRCC6 ZZZ3	63 interactors: AMOTL2 AR ARID2 BAZ1B BRMS1 CCDC136 CCDC172 CDR2 CEP170P1 CEP63 CEP70 DISC1 EPS8 ESR1 ESR2 EXOC7 GATA1 GOLGA2 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT15 KRT31 KRT40 KRTAP10-9 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NL NR0B2 NR3C1 NUP62 PGR PRMT5 RALBP1 RARA RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1
Entrez ID		2059	6605
HPRD ID		02563	04382
Ensembl ID		ENSG00000151491	ENSG00000073584
Uniprot IDs		B4DX66 B4E3T6 Q12929	Q969G3
PDB IDs		2E8M
Enriched GO Terms of Interacting Partners?		Cell Differentiation Developmental Process Movement Of Cell Or Subcellular Component Multicellular Organismal Development System Development Anatomical Structure Development Cell Projection Morphogenesis Cell Part Morphogenesis Axonogenesis Axon Guidance Fc Receptor Signaling Pathway Axon Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Chemotaxis Neurogenesis Neuron Projection Development Immune Response-regulating Signaling Pathway Neuron Projection Morphogenesis Organelle Organization Positive Regulation Of Signal Transduction Cell Morphogenesis Leukocyte Migration Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Generation Of Neurons Cell Development Response To External Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Development Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Blood Coagulation Fibroblast Growth Factor Receptor Signaling Pathway Hemostasis Regulation Of ERBB Signaling Pathway Nervous System Development Innate Immune Response Anatomical Structure Formation Involved In Morphogenesis Regulation Of Protein Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Phosphorylation Regulation Of Immune System Process Platelet Activation Response To Fibroblast Growth Factor	Intracellular Steroid Hormone Receptor Signaling Pathway Intracellular Receptor Signaling Pathway Transcription, DNA-templated Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Organelle Organization Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Positive Regulation Of Macromolecule Biosynthetic Process Chromatin Modification Transcription From RNA Polymerase II Promoter Chromosome Organization RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Hormone Stimulus Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Response To Steroid Hormone Stimulus Hormone-mediated Signaling Pathway Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Histone Modification Negative Regulation Of Gene Expression Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Hormone Gland Development Cellular Response To Organic Cyclic Compound Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Negative Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Steroid Hormone Negative Regulation Of Nucleic Acid-templated Transcription Organ Development Negative Regulation Of RNA Biosynthetic Process Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Signal Transduction
Tagcloud ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound	acetylase aldh1a3 belonging bipotent cbx6 ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico subpopulations trithorax
Tagcloud (Difference) ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound	acetylase aldh1a3 belonging bipotent cbx6 ccnb1 ccne1 committed differentiated disrupt dysregulation encode establishment gata3 hat1 hdac1 identity luminal maintenance myoepithelial notch4 pcgf2 polycomb progenitors silico subpopulations trithorax
Tagcloud (Intersection) ?