EPS8 and SOS1

  • Number of citations of the paper that reports this interaction (PMID 10499589)
  • 82
  • Data Source:
  • HPRD (in vitro)

EPS8

SOS1

Gene Name epidermal growth factor receptor pathway substrate 8 son of sevenless homolog 1 (Drosophila)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions 54 interactors: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BYSL C17orf59 C19orf25 C8orf33 CASK CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RFXAP RUNX1T1 SCRN3 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XRCC6 ZZZ3 52 interactors: ABI1 ABI3 ANXA2 ATP6V1E1 BIN1 CAV1 CD19 CD2AP CRK CRKL CSF1R EGFR EPS8 EPS8L1 EPS8L2 ERBB2 ERBB3 ESR1 FGFR1 FRS2 FYN GAB1 GRAP GRB2 HCK HDLBP HRAS ITSN1 ITSN2 LAT2 LCK MAPK1 MUC1 NCK1 NCK2 PACSIN1 PACSIN3 PIK3R2 PLCG1 PTPN11 PTPN6 RANBP9 RIT2 RRAS SH3BP5 SH3KBP1 SHC1 SNX18 SNX9 SPTAN1 TNIK ZAP70
Entrez ID 2059 6654
HPRD ID 02563 01681
Ensembl ID ENSG00000151491 ENSG00000115904
Uniprot IDs B4DX66 B4E3T6 Q12929 G5E9C8 Q07889
PDB IDs 2E8M 1AWE 1BKD 1DBH 1NVU 1NVV 1NVW 1NVX 1Q9C 1XD2 1XD4 1XDV 2II0 3KSY
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adjacent  breast  cadherin  cisplatin  colony  ectopic  egf  emt  erk  filopodia  g418  healing  invasive  knockdown  lentiviral  mb231  mb468  mcf7  mda  mmp9  mtt  overexpressed  possibly  shrna  stably  transition  vimentin  weakly  wound 
accordingly  antisense  b9  cascade  cascades  distal  gp130  il  independently  jak  lines  mapk  mediates  mediating  mitogen  mm  myeloma  next  occur  oligonucleotide  proliferated  proliferative  ras  regardless  sense  shc  stat1  stat3  triggered 
Tagcloud (Difference) ?
adjacent  breast  cadherin  cisplatin  colony  ectopic  egf  emt  erk  filopodia  g418  healing  invasive  knockdown  lentiviral  mb231  mb468  mcf7  mda  mmp9  mtt  overexpressed  possibly  shrna  stably  transition  vimentin  weakly  wound 
accordingly  antisense  b9  cascade  cascades  distal  gp130  il  independently  jak  lines  mapk  mediates  mediating  mitogen  mm  myeloma  next  occur  oligonucleotide  proliferated  proliferative  ras  regardless  sense  shc  stat1  stat3  triggered 
Tagcloud (Intersection) ?