ITSN2 and MBNL1

Number of citations of the paper that reports this interaction (PMID 22558309)
5

Data Source:
BioGRID (two hybrid)

		ITSN2	MBNL1
Gene Name		intersectin 2	muscleblind-like splicing regulator 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Centrosome Cytoplasmic Stress Granule
	Molecular Function	SH3/SH2 Adaptor Activity Rho Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	RNA Binding Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Endocytosis Positive Regulation Of Signal Transduction Positive Regulation Of Rho GTPase Activity	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Selection Nervous System Development Skeletal Muscle Tissue Development RNA Splicing Embryonic Limb Morphogenesis Regulation Of RNA Splicing Myoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Working memory ( 21107309)	Infantile hypertrophic pyloric stenosis ( 22306654)
Protein-Protein Interactions		75 interactors: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EPS15 EPS15L1 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREML GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	9 interactors: ABI3BP AEN AES APP BIN1 DAB1 IDH3A ITSN2 ZNHIT3
Entrez ID		50618	4154
HPRD ID		09193	07355
Ensembl ID		ENSG00000198399	ENSG00000152601
Uniprot IDs		A6H8W8 Q9NZM3	Q86VM6 Q9NR56
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY	3D2N 3D2Q 3D2S
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cell Communication Signaling Cellular Response To Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cellular Component Assembly Signal Transduction Synaptic Vesicle Transport Enzyme Linked Receptor Protein Signaling Pathway Actin Filament-based Movement Cell-cell Signaling Response To Stimulus Establishment Of Vesicle Localization Cell Surface Receptor Signaling Pathway Vesicle Localization Organelle Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cellular Process Negative Regulation Of Membrane Tubulation Regulation Of Signaling Protein Complex Assembly Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Vesicle Organization Establishment Of Organelle Localization Positive Regulation Of Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Immune Response-regulating Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Positive Regulation Of Cell Death Transport Apoptotic Process Cellular Localization Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Differentiation Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Establishment Of Localization In Cell Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway	Regulation Of Astrocyte Differentiation Regulation Of Glial Cell Differentiation Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Regulation Of Gliogenesis Lipid Tube Assembly Cerebellum Structural Organization Synaptic Growth At Neuromuscular Junction Adult Locomotory Behavior Regulation Of Neuron Differentiation Collateral Sprouting In Absence Of Injury Lateral Motor Column Neuron Migration Dendrite Development Regulation Of Protein Binding Spinal Cord Motor Neuron Migration Positive Regulation Of Anoikis Endocytosis Positive Regulation Of Catalytic Activity Adult Behavior Radial Glia Guided Migration Of Purkinje Cell Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Neurogenesis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Neuron Differentiation Axon Choice Point Recognition Regulation Of Cell Development Locomotory Behavior Neuron Remodeling Positive Regulation Of Astrocyte Differentiation Regulation Of Binding
Tagcloud ?		abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates	arntl2 atlantic clock clocks cry1b cry2 cry3 cryptochrome gadus kaput minded morhua muscleblind myf5 npas1 npas2 nr1d1 nr1d2a ontogenesis oscillators per2a per2b rhythmicity rora synteny teleosts tetrapods timeless translocator
Tagcloud (Difference) ?		abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates	arntl2 atlantic clock clocks cry1b cry2 cry3 cryptochrome gadus kaput minded morhua muscleblind myf5 npas1 npas2 nr1d1 nr1d2a ontogenesis oscillators per2a per2b rhythmicity rora synteny teleosts tetrapods timeless translocator
Tagcloud (Intersection) ?