EPS8 and C17orf59

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EPS8	C17orf59
Gene Name		epidermal growth factor receptor pathway substrate 8	chromosome 17 open reading frame 59
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cell Cortex Postsynaptic Density N-methyl-D-aspartate Selective Glutamate Receptor Complex Cell Junction Growth Cone Vesicle Stereocilium Ruffle Membrane Extracellular Vesicular Exosome
	Molecular Function	Actin Binding SH3/SH2 Adaptor Activity Protein Binding Rac GTPase Binding
	Biological Process	Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Cell Proliferation Adult Locomotory Behavior Regulation Of Cell Shape Positive Regulation Of Signal Transduction Exit From Mitosis Rac Protein Signal Transduction Regulation Of Actin Filament Length Actin Cytoskeleton Reorganization Dendritic Cell Migration Behavioral Response To Ethanol Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Actin Crosslink Formation Actin Polymerization-dependent Cell Motility
Pathways
Drugs
Diseases
GWAS		Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		54 interactors: ABI1 ACTA1 ADAM22 AIMP2 ALDH7A1 ARMC1 BAIAP2 BCKDK BLOC1S6 BYSL C17orf59 C19orf25 C8orf33 CASK CCDC85B CSNK2B CTNNA3 CXCL2 DNALI1 DVL1 EGFR GOLGA8EP GRB2 GULP1 HNRNPC HOOK2 INPP5J ITGB1 ITGB3 ITGB5 MAP1LC3B MAP3K11 MRPL20 MYO15A NACC2 NFKB2 PCM1 PROSER2 RFXAP RUNX1T1 SCRN3 SF3B3 SHB SHC1 SLC27A4 SMARCE1 SOS1 SRC TDP2 TEX28 TPRN USP6NL XRCC6 ZZZ3	5 interactors: EPS8 FBXO44 MOS PLA2G4A SHPRH
Entrez ID		2059	54785
HPRD ID		02563	13368
Ensembl ID		ENSG00000151491	ENSG00000196544
Uniprot IDs		B4DX66 B4E3T6 Q12929	Q96GS4
PDB IDs		2E8M
Enriched GO Terms of Interacting Partners?		Cell Differentiation Developmental Process Movement Of Cell Or Subcellular Component Multicellular Organismal Development System Development Anatomical Structure Development Cell Projection Morphogenesis Cell Part Morphogenesis Axonogenesis Axon Guidance Fc Receptor Signaling Pathway Axon Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Chemotaxis Neurogenesis Neuron Projection Development Immune Response-regulating Signaling Pathway Neuron Projection Morphogenesis Organelle Organization Positive Regulation Of Signal Transduction Cell Morphogenesis Leukocyte Migration Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Generation Of Neurons Cell Development Response To External Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Development Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Blood Coagulation Fibroblast Growth Factor Receptor Signaling Pathway Hemostasis Regulation Of ERBB Signaling Pathway Nervous System Development Innate Immune Response Anatomical Structure Formation Involved In Morphogenesis Regulation Of Protein Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Phosphorylation Regulation Of Immune System Process Platelet Activation Response To Fibroblast Growth Factor	Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Actin Polymerization-dependent Cell Motility Negative Regulation Of Meiotic Cell Cycle Phase Transition Platelet Activating Factor Biosynthetic Process Platelet Activating Factor Metabolic Process Establishment Of Meiotic Spindle Localization Exit From Mitosis Cardiolipin Acyl-chain Remodeling Behavioral Response To Ethanol Cardiolipin Metabolic Process Meiotic Spindle Organization Arachidonic Acid Secretion Phosphatidylinositol Acyl-chain Remodeling Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Rac Protein Signal Transduction Phosphatidylethanolamine Acyl-chain Remodeling Cellular Response To Antibiotic Barbed-end Actin Filament Capping Actin Crosslink Formation Dendritic Cell Migration Phosphatidylcholine Acyl-chain Remodeling Cellular Response To Toxic Substance Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Phospholipid Catabolic Process Phosphatidylserine Metabolic Process Negative Regulation Of Meiotic Cell Cycle Chromatin Organization Cellular Response To Stimulus Long-chain Fatty Acid Transport Regulation Of Meiosis Establishment Of Spindle Orientation Actin Filament Capping Icosanoid Biosynthetic Process Regulation Of Organelle Organization Organelle Organization Regulation Of Meiotic Cell Cycle Spindle Localization Phosphatidylcholine Metabolic Process Negative Regulation Of Actin Filament Depolymerization Response To Antibiotic Acid Secretion Fatty Acid Transport Chromosome Organization Actin Cytoskeleton Reorganization Cell Cycle Process Actin Filament Bundle Assembly Arachidonic Acid Metabolic Process
Tagcloud ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound
Tagcloud (Difference) ?		adjacent breast cadherin cisplatin colony ectopic egf emt erk filopodia g418 healing invasive knockdown lentiviral mb231 mb468 mcf7 mda mmp9 mtt overexpressed possibly shrna stably transition vimentin weakly wound
Tagcloud (Intersection) ?