ITSN2 and SNAP29

Number of citations of the paper that reports this interaction (PMID 22558309)
5

Data Source:
BioGRID (two hybrid)

		ITSN2	SNAP29
Gene Name		intersectin 2	synaptosomal-associated protein, 29kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Extracellular Vesicular Exosome	Cytoplasm Centrosome Plasma Membrane Cell Junction SNARE Complex Neuron Projection Synapse
	Molecular Function	SH3/SH2 Adaptor Activity Rho Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	SNAP Receptor Activity Syntaxin Binding
	Biological Process	Endocytosis Positive Regulation Of Signal Transduction Positive Regulation Of Rho GTPase Activity	Autophagic Vacuole Fusion Exocytosis Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Working memory ( 21107309)
Protein-Protein Interactions		75 interactors: AGT AHDC1 AMPH ANKRD17 BCCIP CBL CCDC88C CHIC2 CPSF6 DLGAP1 DNM2 DST EPS15 EPS15L1 ERC1 FASLG FCHSD1 FCHSD2 FNBP4 GAREML GOLGA2 GOLGA8A GOLGB1 GPNMB HNRNPK HOOK2 ITPKA ITSN1 KCTD10 KDM1A KHDRBS1 KIAA1549 KXD1 LARP6 LSM8 LTBP4 LUC7L3 MAP4K3 MBNL1 MEGF10 NBR1 NR2C2 PDCD6IP PDE4DIP PIK3AP1 PIK3C2B PSEN1 PTN RABEP1 RAD9A RBMX REPS1 RNF20 ROCK1 RUFY1 SEMA6A SH3GL1 SH3KBP1 SNAP29 SOS1 SOS2 STX4 SYN1 SYNJ2 TACC1 TBL3 TMF1 TRIO WAS WASF2 WASL WIPF1 WIPF2 YLPM1 YTHDF1	22 interactors: AP2A1 ATF4 CD7 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 RASSF7 STX12 STX17 STX1A STX3 STX4 STX6 STX7 VAMP1 VAMP2 VAMP4 VAMP5 VAMP7
Entrez ID		50618	9342
HPRD ID		09193	11968
Ensembl ID		ENSG00000198399	ENSG00000099940
Uniprot IDs		A6H8W8 Q9NZM3	O95721
PDB IDs		1J3T 1UDL 1UE9 1UFF 1UHF 3GF9 3JZY
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cell Communication Signaling Cellular Response To Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cellular Component Assembly Signal Transduction Synaptic Vesicle Transport Enzyme Linked Receptor Protein Signaling Pathway Actin Filament-based Movement Cell-cell Signaling Response To Stimulus Establishment Of Vesicle Localization Cell Surface Receptor Signaling Pathway Vesicle Localization Organelle Localization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Cellular Process Negative Regulation Of Membrane Tubulation Regulation Of Signaling Protein Complex Assembly Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Vesicle Organization Establishment Of Organelle Localization Positive Regulation Of Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Immune Response-regulating Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Positive Regulation Of Cell Death Transport Apoptotic Process Cellular Localization Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Differentiation Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Establishment Of Localization In Cell Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway	Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Vesicle-mediated Transport Membrane Organization Intracellular Protein Transport Establishment Of Localization In Cell Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Cellular Localization Vesicle Docking SNARE Complex Assembly Membrane Docking Exocytosis Protein Localization Endomembrane System Organization Golgi Vesicle Transport Secretion By Cell Post-Golgi Vesicle-mediated Transport Organelle Organization Neurotransmitter Secretion Secretion Transport Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Neurotransmitter Levels Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Exocytosis Regulation Of Protein Localization Neurotransmitter Transport Golgi Organization Regulation Of Vesicle-mediated Transport Establishment Of Protein Localization To Plasma Membrane Endosomal Transport Golgi To Plasma Membrane Protein Transport Regulation Of Cellular Localization Eosinophil Degranulation Synaptic Vesicle Transport Positive Regulation Of Synaptic Transmission Golgi To Plasma Membrane Transport Calcium Ion-dependent Exocytosis Protein Localization To Plasma Membrane Regulation Of Exocytosis Long-term Synaptic Potentiation Golgi Ribbon Formation Protein Complex Assembly Positive Regulation Of Protein Localization To Cell Surface Positive Regulation Of Exocytosis
Tagcloud ?		abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates	92e accumulates architecture asparagine autophagic autophagosomes cednik dispensable distinctive dysgenesis highlighting hop hopscotch ichthyosis keratoderma localizes neuropathy npf nsf organelles palmoplantar phenylalanine routes snare stat92e synaptosomal trafficking uncharacterized unlikely
Tagcloud (Difference) ?		abl1 adaptor clathrin colocalize crk domains enabled endocytosis fgr fyn hela interactors interface intersectin isoform isoforms itsn1 itsns mentioned paralogous pathologies phospholipase scaffolding sh2 sh3 tyrosines unable vertebrates	92e accumulates architecture asparagine autophagic autophagosomes cednik dispensable distinctive dysgenesis highlighting hop hopscotch ichthyosis keratoderma localizes neuropathy npf nsf organelles palmoplantar phenylalanine routes snare stat92e synaptosomal trafficking uncharacterized unlikely
Tagcloud (Intersection) ?