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ITSN2 and CHIC2
Number of citations of the paper that reports this interaction (PMID
22558309
)
5
Data Source:
BioGRID
(two hybrid)
ITSN2
CHIC2
Gene Name
intersectin 2
cysteine-rich hydrophobic domain 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Extracellular Vesicular Exosome
Cellular_component
Golgi-associated Vesicle
Plasma Membrane
Molecular Function
SH3/SH2 Adaptor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Molecular_function
Protein Binding
Biological Process
Endocytosis
Positive Regulation Of Signal Transduction
Positive Regulation Of Rho GTPase Activity
Golgi To Plasma Membrane Transport
Biological_process
Pathways
Drugs
Diseases
GWAS
Working memory (
21107309
)
Blood pressure (
21909110
)
Protein-Protein Interactions
75 interactors:
AGT
AHDC1
AMPH
ANKRD17
BCCIP
CBL
CCDC88C
CHIC2
CPSF6
DLGAP1
DNM2
DST
EPS15
EPS15L1
ERC1
FASLG
FCHSD1
FCHSD2
FNBP4
GAREML
GOLGA2
GOLGA8A
GOLGB1
GPNMB
HNRNPK
HOOK2
ITPKA
ITSN1
KCTD10
KDM1A
KHDRBS1
KIAA1549
KXD1
LARP6
LSM8
LTBP4
LUC7L3
MAP4K3
MBNL1
MEGF10
NBR1
NR2C2
PDCD6IP
PDE4DIP
PIK3AP1
PIK3C2B
PSEN1
PTN
RABEP1
RAD9A
RBMX
REPS1
RNF20
ROCK1
RUFY1
SEMA6A
SH3GL1
SH3KBP1
SNAP29
SOS1
SOS2
STX4
SYN1
SYNJ2
TACC1
TBL3
TMF1
TRIO
WAS
WASF2
WASL
WIPF1
WIPF2
YLPM1
YTHDF1
26 interactors:
CATSPER1
CDR2
CEP44
GMCL1
HOXA1
ITSN2
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP4-12
KRTAP4-2
KRTAP5-9
MDFI
MEOX2
NOTCH2NL
OTX1
PLEKHF2
PNMA1
SPERT
TCF4
TOP3B
TUBGCP4
U2AF2
Entrez ID
50618
26511
HPRD ID
09193
10373
Ensembl ID
ENSG00000198399
ENSG00000109220
Uniprot IDs
A6H8W8
Q9NZM3
Q9UKJ5
PDB IDs
1J3T
1UDL
1UE9
1UFF
1UHF
3GF9
3JZY
Enriched GO Terms of Interacting Partners
?
Vesicle-mediated Transport
Endocytosis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Cell Communication
Signaling
Cellular Response To Stimulus
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Cellular Component Assembly
Signal Transduction
Synaptic Vesicle Transport
Enzyme Linked Receptor Protein Signaling Pathway
Actin Filament-based Movement
Cell-cell Signaling
Response To Stimulus
Establishment Of Vesicle Localization
Cell Surface Receptor Signaling Pathway
Vesicle Localization
Organelle Localization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cellular Component Organization
Regulation Of Cellular Process
Negative Regulation Of Membrane Tubulation
Regulation Of Signaling
Protein Complex Assembly
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger
Vesicle Organization
Establishment Of Organelle Localization
Positive Regulation Of Apoptotic Process
Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Immune Response-regulating Signaling Pathway
Positive Regulation Of ERBB Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Cell Death
Transport
Apoptotic Process
Cellular Localization
Regulation Of Cell Death
Positive Regulation Of Intracellular Signal Transduction
Organelle Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Differentiation
Regulation Of Vesicle-mediated Transport
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Establishment Of Localization In Cell
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Embryonic Organ Morphogenesis
Pattern Specification Process
Embryonic Organ Development
Anterior/posterior Pattern Specification
Embryo Development
Embryonic Morphogenesis
Optokinetic Behavior
Abducens Nerve Formation
Chordate Embryonic Development
Embryo Development Ending In Birth Or Egg Hatching
Facial Nucleus Development
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Catenin Import Into Nucleus
Diencephalon Development
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Inner Ear Morphogenesis
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Rhombomere 4 Development
Semicircular Canal Formation
Developmental Process
Rhombomere 3 Development
Rhombomere 5 Development
Maintenance Of DNA Repeat Elements
Positive Regulation Of Metabolic Process
Embryonic Skeletal System Morphogenesis
Ear Morphogenesis
Organ Morphogenesis
Metencephalon Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Somite Specification
Embryonic Hindgut Morphogenesis
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Blood Vessel Development
Multicellular Organismal Development
Regulation Of Transcription From RNA Polymerase II Promoter
Vasculature Development
Diencephalon Morphogenesis
Embryonic Genitalia Morphogenesis
Regulation Of Cilium Beat Frequency Involved In Ciliary Motility
Embryonic Skeletal System Development
Myoblast Fate Commitment
Hindbrain Development
Single Organism Reproductive Process
Embryonic Neurocranium Morphogenesis
Secretory Granule Localization
Tagcloud
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Difference)
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Intersection)
?