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ITSN2 and RUFY1
Number of citations of the paper that reports this interaction (PMID
22558309
)
5
Data Source:
BioGRID
(two hybrid)
ITSN2
RUFY1
Gene Name
intersectin 2
RUN and FYVE domain containing 1
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Early Endosome Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
SH3/SH2 Adaptor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Protein Binding
Zinc Ion Binding
Lipid Binding
Protein Transporter Activity
Biological Process
Endocytosis
Positive Regulation Of Signal Transduction
Positive Regulation Of Rho GTPase Activity
Endocytosis
Protein Transport
Regulation Of Endocytosis
Pathways
Drugs
Diseases
GWAS
Working memory (
21107309
)
Eating disorders (
22911880
)
Protein-Protein Interactions
75 interactors:
AGT
AHDC1
AMPH
ANKRD17
BCCIP
CBL
CCDC88C
CHIC2
CPSF6
DLGAP1
DNM2
DST
EPS15
EPS15L1
ERC1
FASLG
FCHSD1
FCHSD2
FNBP4
GAREML
GOLGA2
GOLGA8A
GOLGB1
GPNMB
HNRNPK
HOOK2
ITPKA
ITSN1
KCTD10
KDM1A
KHDRBS1
KIAA1549
KXD1
LARP6
LSM8
LTBP4
LUC7L3
MAP4K3
MBNL1
MEGF10
NBR1
NR2C2
PDCD6IP
PDE4DIP
PIK3AP1
PIK3C2B
PSEN1
PTN
RABEP1
RAD9A
RBMX
REPS1
RNF20
ROCK1
RUFY1
SEMA6A
SH3GL1
SH3KBP1
SNAP29
SOS1
SOS2
STX4
SYN1
SYNJ2
TACC1
TBL3
TMF1
TRIO
WAS
WASF2
WASL
WIPF1
WIPF2
YLPM1
YTHDF1
17 interactors:
AP3B2
AP3D1
AP3M1
AP3S1
BMX
DIEXF
EPHA3
GIT2
ITSN2
PIAS2
RAB14
RAB39B
RAB3IP
RAB4A
RAB5A
TCF3
TXNDC17
Entrez ID
50618
80230
HPRD ID
09193
15282
Ensembl ID
ENSG00000198399
ENSG00000176783
Uniprot IDs
A6H8W8
Q9NZM3
A8K7B1
Q96T51
PDB IDs
1J3T
1UDL
1UE9
1UFF
1UHF
3GF9
3JZY
2YQM
2YW8
Enriched GO Terms of Interacting Partners
?
Vesicle-mediated Transport
Endocytosis
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Regulation Of ERBB Signaling Pathway
Cell Communication
Signaling
Cellular Response To Stimulus
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Cellular Component Assembly
Signal Transduction
Synaptic Vesicle Transport
Enzyme Linked Receptor Protein Signaling Pathway
Actin Filament-based Movement
Cell-cell Signaling
Response To Stimulus
Establishment Of Vesicle Localization
Cell Surface Receptor Signaling Pathway
Vesicle Localization
Organelle Localization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Cellular Component Organization
Regulation Of Cellular Process
Negative Regulation Of Membrane Tubulation
Regulation Of Signaling
Protein Complex Assembly
Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger
Vesicle Organization
Establishment Of Organelle Localization
Positive Regulation Of Apoptotic Process
Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Immune Response-regulating Signaling Pathway
Positive Regulation Of ERBB Signaling Pathway
Movement Of Cell Or Subcellular Component
Positive Regulation Of Cell Death
Transport
Apoptotic Process
Cellular Localization
Regulation Of Cell Death
Positive Regulation Of Intracellular Signal Transduction
Organelle Organization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Differentiation
Regulation Of Vesicle-mediated Transport
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Establishment Of Localization In Cell
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Anterograde Synaptic Vesicle Transport
Intracellular Protein Transport
Anterograde Axon Cargo Transport
Synaptic Vesicle Transport
Axon Cargo Transport
Rab Protein Signal Transduction
Cellular Protein Localization
Protein Transport
Vesicle-mediated Transport
Establishment Of Protein Localization
Establishment Of Vesicle Localization
Intracellular Transport
Vesicle Localization
Protein Localization
Microtubule-based Transport
Establishment Of Organelle Localization
Cytoskeleton-dependent Intracellular Transport
Establishment Of Localization In Cell
Signaling
Cell Communication
Organelle Localization
Cellular Localization
Ras Protein Signal Transduction
Post-Golgi Vesicle-mediated Transport
Synaptic Transmission
Microtubule-based Movement
Cytoplasmic Transport
Cell-cell Signaling
Endosomal Transport
Regulation Of Ras GTPase Activity
Transport
Phagolysosome Assembly Involved In Apoptotic Cell Clearance
Small GTPase Mediated Signal Transduction
Golgi Vesicle Transport
Regulation Of Ras Protein Signal Transduction
Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Synaptic Vesicle Membrane Organization
Cellular Response To Stimulus
Regulation Of Small GTPase Mediated Signal Transduction
Microtubule-based Process
Regulation Of GTPase Activity
Canonical Wnt Signaling Pathway
Receptor Internalization Involved In Canonical Wnt Signaling Pathway
Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis
Regulation Of Endosome Size
Response To Stimulus
Membrane Organization
Eye Pigment Biosynthetic Process
Movement Of Cell Or Subcellular Component
Tagcloud
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Difference)
?
abl1
adaptor
clathrin
colocalize
crk
domains
enabled
endocytosis
fgr
fyn
hela
interactors
interface
intersectin
isoform
isoforms
itsn1
itsns
mentioned
paralogous
pathologies
phospholipase
scaffolding
sh2
sh3
tyrosines
unable
vertebrates
Tagcloud (Intersection)
?