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MTNR1A and EEF1G
Number of citations of the paper that reports this interaction (PMID
17215244
)
14
Data Source:
HPRD
(in vivo)
MTNR1A
EEF1G
Gene Name
melatonin receptor 1A
eukaryotic translation elongation factor 1 gamma
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Receptor Complex
Nucleus
Cytosol
Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Melatonin Receptor Activity
Hormone Binding
Organic Cyclic Compound Binding
Translation Elongation Factor Activity
Protein Binding
Biological Process
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Mating Behavior
Circadian Rhythm
Positive Regulation Of CGMP Biosynthetic Process
Translation
Translational Elongation
Response To Virus
Gene Expression
Cellular Protein Metabolic Process
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Translation
Eukaryotic Translation Elongation
Drugs
Ramelteon
Melatonin
Agomelatine
Diseases
GWAS
Obesity (
21552555
)
Protein-Protein Interactions
26 interactors:
CALR
CANX
CNP
DPM1
EEF1G
FLNA
GNA11
GNA13
GNAI1
GNAI2
GNAI3
GNB1
GNB4
GPR50
HNRNPA0
HSPA5
IRS4
LRRC59
MTNR1B
PDIA6
PGRMC1
RAB10
RAC1
RAP1A
TMEM33
VAPB
87 interactors:
ABCC9
ADAP2
AKT1
ARF1
ARIH2
C11orf58
C1orf174
CARS
CBX8
CCDC106
CCT7
CDC42
CDK2AP2
CDK5RAP2
CHFR
CRELD1
CSTF2
CXCL13
DKC1
DLEU1
DRD3
ECH1
EEF1B2
EEF1D
EEF1DP3
EFNA1
EGFR
EID2B
ENOX1
FAM195A
FEN1
FOXG1
GADD45A
GADD45G
GET4
GSK3B
GSTO1
HARS
HDAC5
HLTF
HMOX2
HNRNPH3
ILF2
KARS
KLHL18
LARS
LZTS1
MED31
MLH1
MTNR1A
MVD
NADK
NCK2
NDRG1
NUDT21
NUDT3
NUP85
OGFOD2
PDCD5
PHACTR3
PLEKHA4
PLGRKT
PSMD11
PTK2
PTPN4
PTPRS
RBM6
RECQL5
RGL2
RPL4P5
RPS28
SAT1
SKIL
SNAPIN
SNRPD2
TNNT1
TP53I3
TRIB3
TRIM55
TRIM63
TUBB3
UCHL5
WDR33
YWHAG
ZBED8
ZDHHC17
ZNF24
Entrez ID
4543
1937
HPRD ID
02812
11745
Ensembl ID
ENSG00000168412
ENSG00000254772
Uniprot IDs
P48039
P26641
Q53YD7
PDB IDs
1PBU
Enriched GO Terms of Interacting Partners
?
Platelet Activation
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Blood Coagulation
Hemostasis
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Wound Healing
Cell Activation
Response To Wounding
Signaling
Cell Communication
Response To Stimulus
G-protein Coupled Receptor Signaling Pathway
Signal Transduction
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Response To Organic Substance
Positive Regulation Of Nuclease Activity
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Kinase Activity
Vesicle-mediated Transport
Positive Regulation Of Transferase Activity
Response To Stress
Synaptic Transmission
Cell-cell Signaling
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Unfolded Protein
ER-nucleus Signaling Pathway
Cellular Response To Stimulus
Cellular Response To Topologically Incorrect Protein
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Protein Kinase Activity
Dopamine Receptor Signaling Pathway
Substantia Nigra Development
Cellular Response To Organic Substance
Response To Unfolded Protein
Regulation Of Kinase Activity
Membrane Organization
Positive Regulation Of Phosphorylation
Response To Endoplasmic Reticulum Stress
Cell Surface Receptor Signaling Pathway
Neural Nucleus Development
Positive Regulation Of Protein Modification Process
Ras Protein Signal Transduction
Regulation Of Protein Phosphorylation
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Kinase Activity
Response To Peptide Hormone
Midbrain Development
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Macromolecule Biosynthetic Process
Cellular Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Cellular Macromolecule Biosynthetic Process
Biosynthetic Process
Positive Regulation Of Signal Transduction
Cell Cycle Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Intracellular Transport
Regulation Of Cell Development
Chemotaxis
Regulation Of Protein Kinase Activity
Cell Cycle
Regulation Of Endothelial Cell Migration
Positive Regulation Of Mitochondrion Organization
Regulation Of Kinase Activity
Translation
Negative Regulation Of Transferase Activity
Regulation Of Neuron Differentiation
Negative Regulation Of Protein Kinase Activity
Negative Regulation Of Protein Phosphorylation
Regulation Of Neurogenesis
Positive Regulation Of Transferase Activity
Regulation Of Intracellular Transport
Cellular Response To Mechanical Stimulus
Nervous System Development
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Kinase Activity
MRNA Polyadenylation
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Protein Binding
Regulation Of Epithelial Cell Migration
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Protein Metabolic Process
MRNA 3'-end Processing
Response To Growth Factor
Regulation Of Signal Transduction
Mitotic Cell Cycle
Immune System Process
Regulation Of Cell Projection Organization
Response To UV-A
Regulation Of Catalytic Activity
Tagcloud
?
4egi
antiporter
antitumoral
apparatus
atf4
attenuation
bip
client
consequent
cyclophilin
cystine
eef1a
eif4a
favoring
filters
gcn2
hsp
migrate
nascent
pores
proteostasis
ribavirin
ribosomes
sensitizes
sorcin
tbp7
transwell
trap1
xct
Tagcloud (Difference)
?
4egi
antiporter
antitumoral
apparatus
atf4
attenuation
bip
client
consequent
cyclophilin
cystine
eef1a
eif4a
favoring
filters
gcn2
hsp
migrate
nascent
pores
proteostasis
ribavirin
ribosomes
sensitizes
sorcin
tbp7
transwell
trap1
xct
Tagcloud (Intersection)
?