EEF1G and DLEU1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1G	DLEU1
Gene Name		eukaryotic translation elongation factor 1 gamma	deleted in lymphocytic leukemia 1 (non-protein coding)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane Extracellular Vesicular Exosome
	Molecular Function	Translation Elongation Factor Activity Protein Binding
	Biological Process	Translation Translational Elongation Response To Virus Gene Expression Cellular Protein Metabolic Process
Pathways		Translation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS			Multiple sclerosis ( 21833088)
Protein-Protein Interactions		87 interactors: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EGFR EID2B ENOX1 FAM195A FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS KLHL18 LARS LZTS1 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	19 interactors: ABCD4 ABCF3 ARL8B CCDC90B COPS6 EEF1A1 EEF1G GDF9 KAT5 KIAA1377 MED31 PSMA1 SETDB1 SHMT1 TLE1 TP53 TUBB4B UBR1 UTP14A
Entrez ID		1937	10301
HPRD ID		11745	16150
Ensembl ID		ENSG00000254772	ENSG00000176124
Uniprot IDs		P26641 Q53YD7
PDB IDs		1PBU
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Signal Transduction Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Cell Development Chemotaxis Regulation Of Protein Kinase Activity Cell Cycle Regulation Of Endothelial Cell Migration Positive Regulation Of Mitochondrion Organization Regulation Of Kinase Activity Translation Negative Regulation Of Transferase Activity Regulation Of Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Neurogenesis Positive Regulation Of Transferase Activity Regulation Of Intracellular Transport Cellular Response To Mechanical Stimulus Nervous System Development Cellular Response To Growth Factor Stimulus Negative Regulation Of Kinase Activity MRNA Polyadenylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Binding Regulation Of Epithelial Cell Migration Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process MRNA 3'-end Processing Response To Growth Factor Regulation Of Signal Transduction Mitotic Cell Cycle Immune System Process Regulation Of Cell Projection Organization Response To UV-A Regulation Of Catalytic Activity	DNA Damage Response, Signal Transduction By P53 Class Mediator DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction In Response To DNA Damage DNA Damage Response, Signal Transduction Resulting In Transcription Signal Transduction By P53 Class Mediator Negative Regulation Of Fibroblast Proliferation Viral Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Mitotic Cell Cycle Process Negative Regulation Of Macromitophagy Cellular Response To Leucine Oocyte Growth Oligodendrocyte Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter Water-soluble Vitamin Metabolic Process Mitotic Cell Cycle Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic DNA Damage Checkpoint Negative Regulation Of Helicase Activity Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Arrest Cell Cycle Cellular Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Nitrogen Compound Metabolic Process Protein Tetramerization L-serine Catabolic Process Regulation Of Progesterone Secretion Vitamin Metabolic Process Carnitine Biosynthetic Process Positive Regulation Of Protein Modification Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spindle Organization Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Metabolic Process Notch Signaling Pathway Transcription, DNA-templated
Tagcloud ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct	10q23 11q22 12p13 13q14 17p13 21q22 2p23 5q32 6q21 7p12 7q21 8q24 9p13 9p21 9p24 acgh dleu2 ebf1 ikzf1 imbalances interrogate mir145a mir146a mir15a mlpa pax5 probemix uncovering undetected
Tagcloud (Difference) ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct	10q23 11q22 12p13 13q14 17p13 21q22 2p23 5q32 6q21 7p12 7q21 8q24 9p13 9p21 9p24 acgh dleu2 ebf1 ikzf1 imbalances interrogate mir145a mir146a mir15a mlpa pax5 probemix uncovering undetected
Tagcloud (Intersection) ?