EEF1G and HNRNPH3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		EEF1G	HNRNPH3
Gene Name		eukaryotic translation elongation factor 1 gamma	heterogeneous nuclear ribonucleoprotein H3 (2H9)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Spliceosomal Complex
	Molecular Function	Translation Elongation Factor Activity Protein Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Translation Translational Elongation Response To Virus Gene Expression Cellular Protein Metabolic Process	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Epithelial Cell Differentiation
Pathways		Translation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		87 interactors: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EGFR EID2B ENOX1 FAM195A FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS KLHL18 LARS LZTS1 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	26 interactors: ANXA11 C14orf1 C17orf85 CCL13 CHERP CRMP1 DDX17 DDX5 EEF1G ERG HNRNPA0 HNRNPA1 HNRNPD HNRNPF HNRNPH1 HNRNPU HNRNPUL1 IL7R KAT5 MAPK6 PIM2 RBM4 RPS4X TTR UTP14A ZMYM2
Entrez ID		1937	3189
HPRD ID		11745	03818
Ensembl ID		ENSG00000254772	ENSG00000096746
Uniprot IDs		P26641 Q53YD7	B4DHY1 P31942 Q53F48
PDB IDs		1PBU
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Signal Transduction Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Cell Development Chemotaxis Regulation Of Protein Kinase Activity Cell Cycle Regulation Of Endothelial Cell Migration Positive Regulation Of Mitochondrion Organization Regulation Of Kinase Activity Translation Negative Regulation Of Transferase Activity Regulation Of Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Neurogenesis Positive Regulation Of Transferase Activity Regulation Of Intracellular Transport Cellular Response To Mechanical Stimulus Nervous System Development Cellular Response To Growth Factor Stimulus Negative Regulation Of Kinase Activity MRNA Polyadenylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Binding Regulation Of Epithelial Cell Migration Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process MRNA 3'-end Processing Response To Growth Factor Regulation Of Signal Transduction Mitotic Cell Cycle Immune System Process Regulation Of Cell Projection Organization Response To UV-A Regulation Of Catalytic Activity	RNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process MRNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Posttranscriptional Regulation Of Gene Expression Circadian Regulation Of Translation Regulation Of Gene Expression Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of MRNA Stability Cellular Metabolic Process Regulation Of RNA Stability Circadian Rhythm Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Skeletal Muscle Cell Differentiation Rhythmic Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To External Stimulus MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Potassium Ion Export Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Regulation Of Heart Rate By Hormone Interleukin-7-mediated Signaling Pathway Response To Virus Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Skeletal Muscle Tissue Development Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Translation Positive Regulation Of Translation Signal Transduction By Phosphorylation Cytokinesis, Completion Of Separation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Processing
Tagcloud ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Difference) ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct
Tagcloud (Intersection) ?