EEF1G and TUBB3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		EEF1G	TUBB3
Gene Name		eukaryotic translation elongation factor 1 gamma	tubulin, beta 3 class III
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm Microtubule Axon Dendrite Neuronal Cell Body Extracellular Vesicular Exosome Cell Periphery
	Molecular Function	Translation Elongation Factor Activity Protein Binding	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Peptide Binding
	Biological Process	Translation Translational Elongation Response To Virus Gene Expression Cellular Protein Metabolic Process	Protein Folding Microtubule-based Process Mitotic Nuclear Division Axon Guidance Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Transmembrane Transport
Pathways		Translation Eukaryotic Translation Elongation	Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane G2/M Transition L1CAM interactions Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Orphan transporters Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs			Epothilone D Epothilone B Ixabepilone
Diseases
GWAS
Protein-Protein Interactions		87 interactors: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EGFR EID2B ENOX1 FAM195A FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS KLHL18 LARS LZTS1 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	27 interactors: ANXA7 ARHGEF7 CAMSAP3 CDKN1A DDX39B EEF1G GABARAP GZMK HEXDC INSM1 KHDRBS1 LAPTM4A LIG1 MRPL28 MTCL1 PHIP PLK1 RCC1 RILPL2 ROBO1 SEL1L3 SMN1 SPTSSA TERF1 TF TK1 TPTE
Entrez ID		1937	10381
HPRD ID		11745	04044
Ensembl ID		ENSG00000254772	ENSG00000258947
Uniprot IDs		P26641 Q53YD7	A8K854 Q13509 Q53G92
PDB IDs		1PBU
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Signal Transduction Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Cell Development Chemotaxis Regulation Of Protein Kinase Activity Cell Cycle Regulation Of Endothelial Cell Migration Positive Regulation Of Mitochondrion Organization Regulation Of Kinase Activity Translation Negative Regulation Of Transferase Activity Regulation Of Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Neurogenesis Positive Regulation Of Transferase Activity Regulation Of Intracellular Transport Cellular Response To Mechanical Stimulus Nervous System Development Cellular Response To Growth Factor Stimulus Negative Regulation Of Kinase Activity MRNA Polyadenylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Binding Regulation Of Epithelial Cell Migration Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process MRNA 3'-end Processing Response To Growth Factor Regulation Of Signal Transduction Mitotic Cell Cycle Immune System Process Regulation Of Cell Projection Organization Response To UV-A Regulation Of Catalytic Activity	Regulation Of Cell Cycle Process Regulation Of Cellular Component Organization Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Mitotic Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Regulation Of Mitotic Nuclear Division Positive Regulation Of Cell Cycle Positive Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Negative Regulation Of Cell Cycle Mitotic Cell Cycle Positive Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Cell Division Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Division Cell Cycle Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Telomere Maintenance Via Telomere Lengthening Mitotic Spindle Assembly Checkpoint Cell Cycle Process Mitotic Cell Cycle Process Mitotic Cell Cycle Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Response To Toxic Substance Negative Regulation Of Chromosome Segregation Cell Division Cytoskeleton Organization Microtubule Bundle Formation Positive Regulation Of Microtubule Motor Activity Fetal Process Involved In Parturition Columnar/cuboidal Epithelial Cell Development Regulation Of DNA Biosynthetic Process Microtubule-based Process Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Epithelial Cell Development Regulation Of Cell Morphogenesis Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Spliceosomal Complex Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct	actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately stmn1 taqman tfrc top2a tyms vegfr2
Tagcloud (Difference) ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct	actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately stmn1 taqman tfrc top2a tyms vegfr2
Tagcloud (Intersection) ?