EEF1G and C1orf174

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1G	C1orf174
Description		eukaryotic translation elongation factor 1 gamma	chromosome 1 open reading frame 174
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	Translation Elongation Factor Activity Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Translation Translational Elongation Response To Virus
Pathways		Eukaryotic Translation Elongation Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Verbal declarative memory ( 25648963)
Interacting Genes		100 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CEBPA CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DLG4 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B EIF4ENIF1 ENOX1 FAM200C FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MBD1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 OGT PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RNF26 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 USP7 WDR33 YWHAG ZDHHC17 ZNF24	9 interacting genes: AKT1 APP COPS6 EEF1G GOLM1 IKZF1 KAT5 MEOX2 TERF2IP
Entrez ID		1937	339448
HPRD ID		11745	17353
Ensembl ID		ENSG00000254772	ENSG00000198912
Uniprot IDs		P26641 Q53YD7	A0A7P0TAC3 Q8IYL3
PDB IDs		1PBU 5DQS 5JPO
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Translation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stress Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Nucleoplasm Positive Regulation Of Proteasomal Protein Catabolic Process Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Neuron Projection Organization MRNA Cleavage And Polyadenylation Specificity Factor Complex TOR Signaling Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Cell Differentiation Eukaryotic Translation Elongation Factor 1 Complex Regulation Of Cell Adhesion Mediated By Integrin Regulation Of TORC1 Signaling Regulation Of TOR Signaling Regulation Of Cellular Component Organization Response To Stress Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Kinase Binding Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Negative Regulation Of Developmental Process Hematopoietic Stem Cell Proliferation Protein Metabolic Process Potassium Channel Activator Activity RNA Metabolic Process Glutamatergic Synapse Negative Regulation Of Proteasomal Protein Catabolic Process PML Body Phosphatidylinositol-3,4-bisphosphate Binding Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process TORC1 Signaling Positive Regulation Of TORC1 Signaling Regulation Of Chromosome Organization Regulation Of Developmental Process Modulation Of Chemical Synaptic Transmission Protein Modification By Small Protein Conjugation	Regulation Of Lipid Metabolic Process CGAS/STING Signaling Pathway Regulation Of Primary Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Toll-like Receptor Signaling Pathway Response To Nerve Growth Factor Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Lymphocyte Migration Positive Regulation Of DNA Metabolic Process Positive Regulation Of Cell Cycle Regulation Of Cellular Response To Stress Regulation Of TRNA Methylation Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Metabolic Process Cellular Response To Nerve Growth Factor Stimulus Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Histone H2AK5 Acetyltransferase Activity Negative Regulation Of DNA Recombination Regulation Of DNA Metabolic Process Positive Regulation Of Cellular Component Organization Positive Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Catabolic Process Negative Regulation Of SREBP Signaling Pathway Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Cell Activation Negative Regulation Of Fatty Acid Beta-oxidation Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of DNA-templated Transcription Mammalian Oogenesis Stage Regulation Of RNA Biosynthetic Process Cytoplasmic Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Positive Regulation Of Organelle Organization Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Regulation Of Innate Immune Response Maintenance Of Protein Location In Mitochondrion Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Postsynapse Organization TRNA (guanine-N7)-methylation Positive Regulation Of Nucleobase-containing Compound Metabolic Process TORC2 Complex Binding
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