EEF1G and GSTO1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		EEF1G	GSTO1
Description		eukaryotic translation elongation factor 1 gamma	glutathione S-transferase omega 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Translation Elongation Factor Activity Protein Binding Cadherin Binding	Glutathione Transferase Activity Protein Binding Oxidoreductase Activity Transferase Activity Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity
	Biological Process	Translation Translational Elongation Response To Virus	Glutathione Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion L-ascorbic Acid Metabolic Process Xenobiotic Catabolic Process Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cellular Response To Arsenic-containing Substance Cellular Oxidant Detoxification
Pathways		Eukaryotic Translation Elongation Signaling by ALK fusions and activated point mutants	Methylation Glutathione conjugation Vitamin C (ascorbate) metabolism Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Glutathione
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Blood protein levels ( 30072576) Metabolite levels ( 23823483)
Interacting Genes		100 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CEBPA CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DLG4 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B EIF4ENIF1 ENOX1 FAM200C FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MBD1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 OGT PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RNF26 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 USP7 WDR33 YWHAG ZDHHC17 ZNF24	10 interacting genes: APP CEP126 CFTR EEF1G FILNC1 HSPB1 KAT5 RBM48 SERPINB5 SETDB1
Entrez ID		1937	9446
HPRD ID		11745	10401
Ensembl ID		ENSG00000254772	ENSG00000148834
Uniprot IDs		P26641 Q53YD7	P78417 V9HWG9
PDB IDs		1PBU 5DQS 5JPO	1EEM 3LFL 3VLN 4IS0 4YQM 4YQU 4YQV 5UEH 5V3Q 5YVN 5YVO 6MHB 6MHC 6MHD 6PNM 6PNN 6PNO
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Translation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stress Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Nucleoplasm Positive Regulation Of Proteasomal Protein Catabolic Process Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Neuron Projection Organization MRNA Cleavage And Polyadenylation Specificity Factor Complex TOR Signaling Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Cell Differentiation Eukaryotic Translation Elongation Factor 1 Complex Regulation Of Cell Adhesion Mediated By Integrin Regulation Of TORC1 Signaling Regulation Of TOR Signaling Regulation Of Cellular Component Organization Response To Stress Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Kinase Binding Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Negative Regulation Of Developmental Process Hematopoietic Stem Cell Proliferation Protein Metabolic Process Potassium Channel Activator Activity RNA Metabolic Process Glutamatergic Synapse Negative Regulation Of Proteasomal Protein Catabolic Process PML Body Phosphatidylinositol-3,4-bisphosphate Binding Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process TORC1 Signaling Positive Regulation Of TORC1 Signaling Regulation Of Chromosome Organization Regulation Of Developmental Process Modulation Of Chemical Synaptic Transmission Protein Modification By Small Protein Conjugation	Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Positive Regulation Of Interleukin-1 Production Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Regulation Of Response To Calcium Ion Positive Regulation Of Tumor Necrosis Factor Production Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Positive Regulation Of Interleukin-1 Beta Production Lipoprotein Particle Serine-type Endopeptidase Inhibitor Activity Microtubule-based Process Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Regulation Of Interleukin-1 Beta Production Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Negative Regulation Of Protein Kinase C Signaling Protein Kinase C Inhibitor Activity Cornified Envelope Histone H2AK5 Acetyltransferase Activity Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity Histone H2A Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Interleukin-1 Production Cellular Response To Norepinephrine Stimulus Chromatin Binding Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization
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