Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
MTNR1A and CNP
Number of citations of the paper that reports this interaction (PMID
17215244
)
14
Data Source:
HPRD
(in vivo)
MTNR1A
CNP
Gene Name
melatonin receptor 1A
2,3-cyclic nucleotide 3 phosphodiesterase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Receptor Complex
Extracellular Space
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Mitochondrial Inner Membrane
Microtubule
Plasma Membrane
Microvillus
Membrane
Pseudopodium
Myelin Sheath Abaxonal Region
Myelin Sheath Adaxonal Region
Melanosome
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Melatonin Receptor Activity
Hormone Binding
Organic Cyclic Compound Binding
RNA Binding
2',3'-cyclic-nucleotide 3'-phosphodiesterase Activity
Cyclic Nucleotide Binding
Biological Process
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Mating Behavior
Circadian Rhythm
Positive Regulation Of CGMP Biosynthetic Process
Microtubule Cytoskeleton Organization
Synaptic Transmission
Axonogenesis
Aging
Adult Locomotory Behavior
Cyclic Nucleotide Catabolic Process
Response To Toxic Substance
Substantia Nigra Development
Forebrain Development
Response To Lipopolysaccharide
Regulation Of Mitochondrial Membrane Permeability
Oligodendrocyte Differentiation
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Ramelteon
Melatonin
Agomelatine
Diseases
GWAS
Obesity (
21552555
)
Protein-Protein Interactions
26 interactors:
CALR
CANX
CNP
DPM1
EEF1G
FLNA
GNA11
GNA13
GNAI1
GNAI2
GNAI3
GNB1
GNB4
GPR50
HNRNPA0
HSPA5
IRS4
LRRC59
MTNR1B
PDIA6
PGRMC1
RAB10
RAC1
RAP1A
TMEM33
VAPB
5 interactors:
MTNR1A
PPP1CA
PRKCD
PRNP
TUBA1A
Entrez ID
4543
1267
HPRD ID
02812
00448
Ensembl ID
ENSG00000168412
ENSG00000173786
Uniprot IDs
P48039
P09543
PDB IDs
1WOJ
Enriched GO Terms of Interacting Partners
?
Platelet Activation
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Blood Coagulation
Hemostasis
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Regulation Of Body Fluid Levels
Wound Healing
Cell Activation
Response To Wounding
Signaling
Cell Communication
Response To Stimulus
G-protein Coupled Receptor Signaling Pathway
Signal Transduction
Activation Of Signaling Protein Activity Involved In Unfolded Protein Response
Response To Organic Substance
Positive Regulation Of Nuclease Activity
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Kinase Activity
Vesicle-mediated Transport
Positive Regulation Of Transferase Activity
Response To Stress
Synaptic Transmission
Cell-cell Signaling
Endoplasmic Reticulum Unfolded Protein Response
Cellular Response To Unfolded Protein
ER-nucleus Signaling Pathway
Cellular Response To Stimulus
Cellular Response To Topologically Incorrect Protein
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Protein Kinase Activity
Dopamine Receptor Signaling Pathway
Substantia Nigra Development
Cellular Response To Organic Substance
Response To Unfolded Protein
Regulation Of Kinase Activity
Membrane Organization
Positive Regulation Of Phosphorylation
Response To Endoplasmic Reticulum Stress
Cell Surface Receptor Signaling Pathway
Neural Nucleus Development
Positive Regulation Of Protein Modification Process
Ras Protein Signal Transduction
Regulation Of Protein Phosphorylation
Regulation Of Phosphorus Metabolic Process
Regulation Of Protein Kinase Activity
Response To Peptide Hormone
Midbrain Development
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Cell Cycle
Negative Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of Phospholipid Scramblase Activity
Positive Regulation Of Glucosylceramide Catabolic Process
Positive Regulation Of Sphingomyelin Catabolic Process
Negative Regulation Of Cell-cell Adhesion
Positive Regulation Of Phospholipid Catabolic Process
Circadian Rhythm
Interleukin-10 Production
Positive Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Cell Adhesion
Negative Regulation Of Filopodium Assembly
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Signal Transduction
Interleukin-12 Production
Negative Regulation Of Signaling
Positive Regulation Of Ceramide Biosynthetic Process
Cellular Response To Copper Ion
Negative Regulation Of Calcium-mediated Signaling
Regulation Of Ceramide Biosynthetic Process
Rhythmic Process
Negative Regulation Of Protein Phosphorylation
Positive Regulation Of Phospholipid Transport
Cellular Response To Stimulus
Negative Regulation Of Platelet Aggregation
Negative Regulation Of Interleukin-17 Production
Positive Regulation Of Superoxide Anion Generation
Regulation Of Glycogen Catabolic Process
Negative Regulation Of Glial Cell Apoptotic Process
Regulation Of Calcineurin-NFAT Signaling Cascade
Regulation Of Apoptotic Process
Regulation Of Phosphorus Metabolic Process
Regulation Of Cell-cell Adhesion
Negative Regulation Of Activated T Cell Proliferation
Regulation Of Cell Death
Negative Regulation Of Phosphorylation
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Superoxide Anion Generation
Response To Oxidative Stress
Cell Division
Regulation Of Platelet Aggregation
Negative Regulation Of Platelet Activation
Positive Regulation Of CGMP Biosynthetic Process
Regulation Of Cell Activation
Negative Regulation Of Interleukin-2 Production
Cellular Copper Ion Homeostasis
Response To External Stimulus
Positive Regulation Of CGMP Metabolic Process
Negative Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of Protein Dephosphorylation
Tagcloud
?
b
blot
caused
culture
e1
exposure
gamma
increases
influence
mc3t3
metabolism
microm
might
moderate
mrnas
natriuretic
northern
npr
osteoblastic
peptide
promotes
rar
retinoic
retinoid
retinoids
rxr
system
unchanged
x
Tagcloud (Difference)
?
b
blot
caused
culture
e1
exposure
gamma
increases
influence
mc3t3
metabolism
microm
might
moderate
mrnas
natriuretic
northern
npr
osteoblastic
peptide
promotes
rar
retinoic
retinoid
retinoids
rxr
system
unchanged
x
Tagcloud (Intersection)
?