EEF1G and MCRIP2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EEF1G	MCRIP2
Description		eukaryotic translation elongation factor 1 gamma	MAPK regulated corepressor interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule
	Molecular Function	Translation Elongation Factor Activity Protein Binding Cadherin Binding	RNA Binding Protein Binding Protein-containing Complex Binding
	Biological Process	Translation Translational Elongation Response To Virus	Fatty Acid Metabolic Process Branched-chain Amino Acid Metabolic Process Response To Cold Gene Expression Cold-induced Thermogenesis
Pathways		Eukaryotic Translation Elongation Signaling by ALK fusions and activated point mutants
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		100 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CEBPA CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DLG4 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B EIF4ENIF1 ENOX1 FAM200C FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MBD1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 OGT PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RNF26 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 USP7 WDR33 YWHAG ZDHHC17 ZNF24	2 interacting genes: EEF1G PIK3CD
Entrez ID		1937	84331
HPRD ID		11745	17503
Ensembl ID		ENSG00000254772	ENSG00000172366
Uniprot IDs		P26641 Q53YD7	Q9BUT9
PDB IDs		1PBU 5DQS 5JPO
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Translation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Stress Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Nucleoplasm Positive Regulation Of Proteasomal Protein Catabolic Process Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Neuron Projection Organization MRNA Cleavage And Polyadenylation Specificity Factor Complex TOR Signaling Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Cell Differentiation Eukaryotic Translation Elongation Factor 1 Complex Regulation Of Cell Adhesion Mediated By Integrin Regulation Of TORC1 Signaling Regulation Of TOR Signaling Regulation Of Cellular Component Organization Response To Stress Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Kinase Binding Regulation Of Protein Catabolic Process Negative Regulation Of Catabolic Process Negative Regulation Of Developmental Process Hematopoietic Stem Cell Proliferation Protein Metabolic Process Potassium Channel Activator Activity RNA Metabolic Process Glutamatergic Synapse Negative Regulation Of Proteasomal Protein Catabolic Process PML Body Phosphatidylinositol-3,4-bisphosphate Binding Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process TORC1 Signaling Positive Regulation Of TORC1 Signaling Regulation Of Chromosome Organization Regulation Of Developmental Process Modulation Of Chemical Synaptic Transmission Protein Modification By Small Protein Conjugation	Positive Regulation Of Myeloid Cell Apoptotic Process Natural Killer Cell Chemotaxis Mast Cell Differentiation Regulation Of Neutrophil Apoptotic Process Positive Regulation Of Neutrophil Apoptotic Process Respiratory Burst Involved In Defense Response Phosphatidylinositol 3-kinase Complex Mast Cell Chemotaxis 1-phosphatidylinositol-4-phosphate 3-kinase Activity Phosphatidylinositol 3-kinase Complex, Class IA Mast Cell Migration 1-phosphatidylinositol-4,5-bisphosphate 3-kinase Activity B Cell Chemotaxis Positive Regulation Of Epithelial Tube Formation Neutrophil Extravasation 1-phosphatidylinositol-3-kinase Activity Translation Elongation Factor Activity T Cell Chemotaxis Vascular Endothelial Growth Factor Signaling Pathway Natural Killer Cell Differentiation Cellular Extravasation Phosphatidylinositol-3-phosphate Biosynthetic Process Respiratory Burst Phosphatidylinositol-mediated Signaling Lymphocyte Chemotaxis Mast Cell Degranulation Positive Regulation Of Leukocyte Apoptotic Process Regulation Of Myeloid Cell Apoptotic Process Response To Other Organism T Cell Migration Positive Regulation Of Morphogenesis Of An Epithelium Leukocyte Degranulation Response To External Biotic Stimulus Lymphocyte Migration Phosphatidylinositol Phosphate Biosynthetic Process Neutrophil Chemotaxis Natural Killer Cell Activation T Cell Costimulation Lysosome Localization B Cell Receptor Signaling Pathway Translational Elongation Neutrophil Migration Regulation Of Morphogenesis Of An Epithelium Granulocyte Chemotaxis Granulocyte Migration Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Endothelial Cell Proliferation Regulated Exocytosis Phosphatidylinositol Biosynthetic Process Mononuclear Cell Migration
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