EEF1G and ABCC9

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		EEF1G	ABCC9
Gene Name		eukaryotic translation elongation factor 1 gamma	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane Extracellular Vesicular Exosome	Plasma Membrane Voltage-gated Potassium Channel Complex ATP-sensitive Potassium Channel Complex Sarcomere Sarcolemma
	Molecular Function	Translation Elongation Factor Activity Protein Binding	Transporter Activity Potassium Channel Activity ATP Binding Sulfonylurea Receptor Activity Potassium Channel Regulator Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Ion Channel Binding
	Biological Process	Translation Translational Elongation Response To Virus Gene Expression Cellular Protein Metabolic Process	Potassium Ion Transport Signal Transduction Synaptic Transmission Metabolic Process Potassium Ion Import Defense Response To Virus Transmembrane Transport
Pathways		Translation Eukaryotic Translation Elongation	Inwardly rectifying K+ channels ABC-family proteins mediated transport ATP sensitive Potassium channels Potassium Channels
Drugs			Adenosine triphosphate Glyburide
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		87 interactors: ABCC9 ADAP2 AKT1 ARF1 ARIH2 C11orf58 C1orf174 CARS CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EGFR EID2B ENOX1 FAM195A FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS KLHL18 LARS LZTS1 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SKIL SNAPIN SNRPD2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24	5 interactors: EEF1G KCNJ11 KCNJ8 LDHA STX1A
Entrez ID		1937	10060
HPRD ID		11745	03258
Ensembl ID		ENSG00000254772	ENSG00000069431
Uniprot IDs		P26641 Q53YD7	O60706
PDB IDs		1PBU
Enriched GO Terms of Interacting Partners?		Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Macromolecule Biosynthetic Process Biosynthetic Process Positive Regulation Of Signal Transduction Cell Cycle Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of Cell Development Chemotaxis Regulation Of Protein Kinase Activity Cell Cycle Regulation Of Endothelial Cell Migration Positive Regulation Of Mitochondrion Organization Regulation Of Kinase Activity Translation Negative Regulation Of Transferase Activity Regulation Of Neuron Differentiation Negative Regulation Of Protein Kinase Activity Negative Regulation Of Protein Phosphorylation Regulation Of Neurogenesis Positive Regulation Of Transferase Activity Regulation Of Intracellular Transport Cellular Response To Mechanical Stimulus Nervous System Development Cellular Response To Growth Factor Stimulus Negative Regulation Of Kinase Activity MRNA Polyadenylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Binding Regulation Of Epithelial Cell Migration Regulation Of Intracellular Signal Transduction Negative Regulation Of Protein Metabolic Process MRNA 3'-end Processing Response To Growth Factor Regulation Of Signal Transduction Mitotic Cell Cycle Immune System Process Regulation Of Cell Projection Organization Response To UV-A Regulation Of Catalytic Activity	Potassium Ion Import Generation Of Precursor Metabolites And Energy Synaptic Transmission Energy Reserve Metabolic Process Cell-cell Signaling Potassium Ion Transmembrane Transport Regulation Of Insulin Secretion Potassium Ion Transport Regulation Of Peptide Hormone Secretion Response To Virus Regulation Of Hormone Secretion Regulation Of Membrane Potential Cellular Response To Nicotine Energy Derivation By Oxidation Of Organic Compounds Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Synaptic Vesicle Fusion To Presynaptic Membrane Oxidation-reduction Process Regulation Of Protein Secretion Regulation Of Ion Transmembrane Transport Response To Gravity Positive Regulation Of Neurotransmitter Secretion Ion Transport Response To External Stimulus Response To Stimulus Glutamate Secretion Response To ATP Regulation Of Ion Transport Regulation Of Protein Transport Positive Regulation Of Cation Channel Activity Regulation Of Secretion Vasodilation Response To Ischemia Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Synaptic Vesicle Exocytosis Monovalent Inorganic Cation Transport Response To PH Regulation Of Establishment Of Protein Localization Response To Testosterone Substantia Nigra Development Response To Nicotine Cellular Response To Alkaloid Small Molecule Metabolic Process Negative Regulation Of Insulin Secretion Response To Other Organism Regulation Of Synaptic Vesicle Transport Positive Regulation Of Membrane Potential Positive Regulation Of Transport Negative Regulation Of Peptide Secretion Response To Biotic Stimulus
Tagcloud ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct	annually arid1a causing chd4 comprehensively deadliest deaths disruption endometrial enriched ep300 etiology exome fbxw7 frequencies grouping implicating ligase map3k4 mutated mutational remodeling resequenced serous sixth somatic spop tspyl2 worldwide
Tagcloud (Difference) ?		4egi antiporter antitumoral apparatus atf4 attenuation bip client consequent cyclophilin cystine eef1a eif4a favoring filters gcn2 hsp migrate nascent pores proteostasis ribavirin ribosomes sensitizes sorcin tbp7 transwell trap1 xct	annually arid1a causing chd4 comprehensively deadliest deaths disruption endometrial enriched ep300 etiology exome fbxw7 frequencies grouping implicating ligase map3k4 mutated mutational remodeling resequenced serous sixth somatic spop tspyl2 worldwide
Tagcloud (Intersection) ?