SERBP1 and FBXO25

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		SERBP1	FBXO25
Gene Name		SERPINE1 mRNA binding protein 1	F-box protein 25
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	MRNA 3'-UTR Binding Protein Binding Poly(A) RNA Binding	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Regulation Of Apoptotic Process Regulation Of MRNA Stability	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 22412388)
Protein-Protein Interactions		20 interactors: APP CHD3 CSNK2A1 DAXX FBXO25 FXYD3 ITFG1 KAT2B PCAP PIAS1 PIAS3 PIAS4 PRMT8 TDG TERT TOPORS UBA2 UPF2 VAV2 VIM	80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1
Entrez ID		26135	26260
HPRD ID		09570	16439
Ensembl ID		ENSG00000142864	ENSG00000147364
Uniprot IDs		Q5VU21 Q63HR1 Q8NC51	Q8TCJ0
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Peptidyl-lysine Modification Positive Regulation Of Protein Sumoylation RNA Metabolic Process Regulation Of Gene Expression Regulation Of Protein Sumoylation Positive Regulation Of Metabolic Process Gene Expression Regulation Of Metabolic Process RNA Biosynthetic Process Peptidyl-amino Acid Modification Chromatin Modification Protein Modification By Small Protein Conjugation Chromatin Organization Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Positive Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Modification Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Programmed Cell Death Negative Regulation Of Cellular Metabolic Process Chromosome Organization Positive Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Cell Death Death Regulation Of Protein Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Protein Binding Positive Regulation Of Cellular Metabolic Process Cellular Protein Metabolic Process Intracellular Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Apoptotic Process Cellular Metabolic Process Regulation Of Cell Death Negative Regulation Of Production Of SiRNA Involved In RNA Interference	Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process
Tagcloud ?		9q altered cgi contexts experimentally explain familiar functionally give habp4 haplotype hek293t identity inducer insights ki knockdown link microchip overexpression paralogs prompting qrt shared similarity sirna thapsigargin transcriptome tumorigenic
Tagcloud (Difference) ?		9q altered cgi contexts experimentally explain familiar functionally give habp4 haplotype hek293t identity inducer insights ki knockdown link microchip overexpression paralogs prompting qrt shared similarity sirna thapsigargin transcriptome tumorigenic
Tagcloud (Intersection) ?