SERBP1 and LINC00624

Number of citations of the paper that reports this interaction (PubMedID 36252997)
50

Data Source:
BioGRID (unspecified method)

		SERBP1	LINC00624
Description		SERPINE1 mRNA binding protein 1	long intergenic non-protein coding RNA 624
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Repressor Activity SUMO Binding Ribosome Binding Cadherin Binding Translation Elongation Factor Binding
	Biological Process	Regulation Of Translation Negative Regulation Of Translation PML Body Organization Regulation Of MRNA Stability Ribosome Hibernation
Pathways
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Carotid plaque burden ( 28282560) Crohn's disease ( 22412388 28067908) DHEAS levels ( 34748635) Inflammatory bowel disease ( 28067908) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 28067908)	Body mass index and systolic blood pressure (bivariate analysis) ( 33539483) End-stage kidney disease ( 31178898) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 31562340) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		27 interacting genes: - APP CHD3 CSNK2A1 DANCR DAXX ESR1 FBXO25 FXYD3 H19 KAT2B LINC00624 OGT PIAS1 PIAS3 PIAS4 PICK1 PRMT8 TDG TERT TOPORS UBA2 UPF2 USP7 VAV2 VIM WEE2-AS1	38 interacting genes: ACTA1 ACTC1 ADAR ALB CCT2 CCT4 CPNE3 DDX42 DDX5 EIF2AK2 FUBP3 G6PD H2BC18 HDAC6 HNRNPL HNRNPM HNRNPU HRNR ILF3 MCCC1 MCCC2 NONO PARP1 PTBP1 PTBP2 PTBP3 SERBP1 SFPQ SND1 SRRT STAU1 STAU2 TRIM28 TUBA1B TUBA1C UBAP2L YBX3 ZNF354C
Entrez ID		26135	100289211
HPRD ID		09570
Ensembl ID		ENSG00000142864	ENSG00000278811
Uniprot IDs		Q5VU21 Q8NC51
PDB IDs		4V6X 6Z6M 6Z6N 8K2C 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X
Enriched GO Terms of Interacting Partners?		PML Body Positive Regulation Of Protein Sumoylation Protein Sumoylation SUMO Transferase Activity Regulation Of Protein Sumoylation SUMO Ligase Activity Transcription Coregulator Activity Regulation Of Post-translational Protein Modification Chromatin Organization Chromatin Remodeling Negative Regulation Of Gene Expression Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Proteolysis Regulation Of Protein Catabolic Process Protein Modification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Enzyme Binding Positive Regulation Of Transcription By Glucose Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Rhythmic Process Carbon Catabolite Regulation Of Transcription Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Positive Regulation Of Post-translational Protein Modification Regulation Of Programmed Cell Death Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Macromolecule Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Gene Expression, Epigenetic Regulation Of Primary Metabolic Process Regulation Of Glycolytic Process Regulation Of Protein Metabolic Process Regulation Of Gluconeogenesis Protein Modification By Small Protein Conjugation Regulation Of Transcription By Glucose Regulation Of Macromolecule Metabolic Process Cellular Response To Stress	RNA Binding RNA Localization Nucleic Acid Binding Double-stranded RNA Binding MRNA Processing MRNA Binding Negative Regulation Of Macromolecule Biosynthetic Process MRNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Viral Genome Replication Negative Regulation Of Metabolic Process Dendritic Transport Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression RNA Splicing Regulation Of Viral Life Cycle RNA Processing Cytoskeleton-dependent Intracellular Transport Alternative MRNA Splicing, Via Spliceosome Regulation Of Viral Process RNA Metabolic Process Cell Body Nucleus Axo-dendritic Transport Paraspeckles Regulation Of Macromolecule Biosynthetic Process Intracellular MRNA Localization Extracellular Exosome Regulation Of RNA Splicing Methylcrotonoyl-CoA Carboxylase Complex Methylcrotonoyl-CoA Carboxylase Activity Regulation Of Telomere Maintenance Via Telomere Lengthening Pre-mRNA Binding Cytoplasm Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Dendritic Transport Of Messenger Ribonucleoprotein Complex Anterograde Dendritic Transport Of Messenger Ribonucleoprotein Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Response To Chemical Stress Negative Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Regulatory NcRNA-mediated Gene Silencing Transport Along Microtubule Binding Of Sperm To Zona Pellucida Mesenchyme Migration ScaRNA Localization To Cajal Body
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