FBXO25 and PRKG2

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		FBXO25	PRKG2
Gene Name		F-box protein 25	protein kinase, cGMP-dependent, type II
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex	Cytosol Apical Plasma Membrane Nuclear Membrane
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding	Protein Kinase Activity CGMP-dependent Protein Kinase Activity ATP Binding CGMP Binding Protein Homodimerization Activity
	Biological Process	Protein Ubiquitination	Protein Phosphorylation Signal Transduction Blood Coagulation Circadian Regulation Of Gene Expression Peptidyl-serine Autophosphorylation Small Molecule Metabolic Process Nitric Oxide Metabolic Process Regulation Of Nitric-oxide Synthase Activity Protein Targeting To Plasma Membrane
Pathways			Metabolism of nitric oxide Platelet homeostasis Ca2+ pathway eNOS activation and regulation Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation Nitric oxide stimulates guanylate cyclase cGMP effects Signaling by Wnt beta-catenin independent WNT signaling
Drugs
Diseases
GWAS			Height ( 19343178 23563607 18391951) HIV-1 susceptibility ( 22174851) Pubertal anthropometrics ( 23449627)
Protein-Protein Interactions		80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1	6 interactors: FBXO25 LASP1 MYLK NEDD4 PLCB3 PTS
Entrez ID		26260	5593
HPRD ID		16439	09034
Ensembl ID		ENSG00000147364	ENSG00000138669
Uniprot IDs		Q8TCJ0	Q13237
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Aorta Smooth Muscle Tissue Morphogenesis Progesterone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Tetrahydrobiopterin Biosynthetic Process Glucocorticoid Receptor Signaling Pathway Tonic Smooth Muscle Contraction Bleb Assembly Protein Targeting To Lysosome Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein Localization To Lysosome
Tagcloud ?			adamts17 arrays besides bioinformatics bmp3 causative classic cnv cnvs duplication effort families gwas height heritable novo pappa pathogenic pathogenicity plates polygenic rodents segregating segregation short shox stature trait tulp4
Tagcloud (Difference) ?			adamts17 arrays besides bioinformatics bmp3 causative classic cnv cnvs duplication effort families gwas height heritable novo pappa pathogenic pathogenicity plates polygenic rodents segregating segregation short shox stature trait tulp4
Tagcloud (Intersection) ?