SERBP1 and FXYD3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SERBP1	FXYD3
Gene Name		SERPINE1 mRNA binding protein 1	FXYD domain containing ion transport regulator 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Extracellular Vesicular Exosome
	Molecular Function	MRNA 3'-UTR Binding Protein Binding Poly(A) RNA Binding	Chloride Channel Activity ATPase Binding
	Biological Process	Regulation Of Apoptotic Process Regulation Of MRNA Stability	Chloride Transport Ion Transmembrane Transport Regulation Of Catalytic Activity Transmembrane Transport Chloride Transmembrane Transport
Pathways			Ion transport by P-type ATPases Ion channel transport
Drugs
Diseases
GWAS		Crohn's disease ( 22412388)
Protein-Protein Interactions		20 interactors: APP CHD3 CSNK2A1 DAXX FBXO25 FXYD3 ITFG1 KAT2B PCAP PIAS1 PIAS3 PIAS4 PRMT8 TDG TERT TOPORS UBA2 UPF2 VAV2 VIM	5 interactors: FBXL12 MAPK6 NR4A1 NUDT3 SERBP1
Entrez ID		26135	5349
HPRD ID		09570	05410
Ensembl ID		ENSG00000142864	ENSG00000089356
Uniprot IDs		Q5VU21 Q63HR1 Q8NC51	Q14802
PDB IDs		3J3A
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Peptidyl-lysine Modification Positive Regulation Of Protein Sumoylation RNA Metabolic Process Regulation Of Gene Expression Regulation Of Protein Sumoylation Positive Regulation Of Metabolic Process Gene Expression Regulation Of Metabolic Process RNA Biosynthetic Process Peptidyl-amino Acid Modification Chromatin Modification Protein Modification By Small Protein Conjugation Chromatin Organization Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated Positive Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Protein Modification Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Apoptotic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Programmed Cell Death Negative Regulation Of Cellular Metabolic Process Chromosome Organization Positive Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Cell Death Death Regulation Of Protein Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Protein Binding Positive Regulation Of Cellular Metabolic Process Cellular Protein Metabolic Process Intracellular Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Apoptotic Process Cellular Metabolic Process Regulation Of Cell Death Negative Regulation Of Production Of SiRNA Involved In RNA Interference	Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process
Tagcloud ?		9q altered cgi contexts experimentally explain familiar functionally give habp4 haplotype hek293t identity inducer insights ki knockdown link microchip overexpression paralogs prompting qrt shared similarity sirna thapsigargin transcriptome tumorigenic	48h acetylated around caco code dex dexamethasone di enhancer glucocorticoid h4 histone histones hormones inactivation induction intestinal intestine k4 lct lox mapk methylated mitogen p44 pd pd98059 scnn1a transcribed
Tagcloud (Difference) ?		9q altered cgi contexts experimentally explain familiar functionally give habp4 haplotype hek293t identity inducer insights ki knockdown link microchip overexpression paralogs prompting qrt shared similarity sirna thapsigargin transcriptome tumorigenic	48h acetylated around caco code dex dexamethasone di enhancer glucocorticoid h4 histone histones hormones inactivation induction intestinal intestine k4 lct lox mapk methylated mitogen p44 pd pd98059 scnn1a transcribed
Tagcloud (Intersection) ?