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FBXO25 and HMCES
Number of citations of the paper that reports this interaction (PMID
23940030
)
0
Data Source:
BioGRID
(enzymatic study)
FBXO25
HMCES
Gene Name
F-box protein 25
5-hydroxymethylcytosine (hmC) binding, ES cell-specific
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleolus
SCF Ubiquitin Ligase Complex
Molecular Function
Actin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
DNA Binding
Peptidase Activity
Biological Process
Protein Ubiquitination
Proteolysis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
80 interactors:
ADRBK1
ANKRD13A
APLF
AXL
BMX
C11orf63
C19orf57
C6orf106
C7orf50
CDK5RAP2
CDK9
CENPB
CUL1
CXXC4
DCX
DDX42
DEPTOR
DNAJB2
DNAJC8
DYRK3
DYRK4
EGFR
EID3
EIF4E2
ELK1
EPN1
FKBP3
G3BP1
GTF2B
GTF2IRD2
HIP1
HMCES
HP1BP3
IL21
ING3
IRS1
KDR
KRT8
LMCD1
LUC7L
MAT2B
NSRP1
NUAK1
ODF2
ORC4
PADI4
PAK4
PCK1
PDGFRA
PIP4K2C
PPID
PPP1R8
PRKCA
PRKG2
PRR15
PRRG1
PSMD4
RABEP2
RBM8A
RHBDD1
RIOK3
RPAP3
RPS10
RPS6KB2
SAMHD1
SERBP1
SKP1
STAC
SYTL2
TCEAL2
TCEANC
TCP10L
TMA7
TNIP2
TRUB1
TWF1
UBE2D3
UBQLN1
UBQLN2
WDSUB1
3 interactors:
APP
FBXO25
NEDD4
Entrez ID
26260
56941
HPRD ID
16439
13119
Ensembl ID
ENSG00000147364
ENSG00000183624
Uniprot IDs
Q8TCJ0
E7EMP6
Q96FZ2
PDB IDs
Enriched GO Terms of Interacting Partners
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Regulation Of Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Peptidyl-amino Acid Modification
Cellular Metabolic Process
Cellular Protein Modification Process
Enzyme Linked Receptor Protein Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Response To Stress
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Innate Immune Response
Neurotrophin Signaling Pathway
Viral Process
Protein Phosphorylation
Cellular Response To Stimulus
Cellular Response To Growth Factor Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
Cellular Protein Metabolic Process
Response To Growth Factor
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Gene Expression
Peptidyl-tyrosine Phosphorylation
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Positive Regulation Of Phospholipase C Activity
Phosphorylation
Intracellular Signal Transduction
Regulation Of Cellular Process
Rhythmic Process
Protein Autophosphorylation
Positive Regulation Of Phospholipase Activity
Response To Stimulus
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Organic Substance
Immune Response
Proteasomal Protein Catabolic Process
G1/S Transition Of Mitotic Cell Cycle
Response To UV-A
Peptidyl-serine Autophosphorylation
Regulation Of Phospholipase Activity
Apoptotic Process
Positive Regulation Of Lipase Activity
Defense Response
Protein Metabolic Process
Regulation Of Cell Death
Immune System Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecule Catabolic Process
Neuromuscular Junction Development
Regulation Of Synapse Structure Or Activity
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Transmission Of Virus
Development Involved In Symbiotic Interaction
Synapse Organization
Intracellular Receptor Signaling Pathway
Synaptic Growth At Neuromuscular Junction
Collateral Sprouting In Absence Of Injury
Collateral Sprouting
Axon Midline Choice Point Recognition
Response To Light Stimulus
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Progesterone Receptor Signaling Pathway
Axon Choice Point Recognition
Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Glucocorticoid Receptor Signaling Pathway
Response To Radiation
Neuron Remodeling
Protein Targeting To Lysosome
Negative Regulation Of Sodium Ion Transport
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Neuron Differentiation
Protein Localization To Lysosome
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Endocytosis
Cellular Copper Ion Homeostasis
Cell Activation
Receptor Catabolic Process
Cellular Protein Modification Process
Regulation Of Neurogenesis
Protein Targeting To Vacuole
Copper Ion Homeostasis
Suckling Behavior
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle
Establishment Of Protein Localization To Vacuole
Neuron Projection Development
Regulation Of Potassium Ion Transmembrane Transporter Activity
Neuron Maturation
MRNA Polyadenylation
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Regulation Of Cell Development
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Protein K63-linked Ubiquitination
Mating Behavior
Endoplasmic Reticulum Calcium Ion Homeostasis
RNA Polyadenylation
Neuron Recognition
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Tagcloud (Difference)
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Tagcloud (Intersection)
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