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FBXO25 and AXL
Number of citations of the paper that reports this interaction (PMID
23940030
)
0
Data Source:
BioGRID
(enzymatic study)
FBXO25
AXL
Gene Name
F-box protein 25
AXL receptor tyrosine kinase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleolus
SCF Ubiquitin Ligase Complex
Extracellular Space
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Extracellular Vesicular Exosome
Molecular Function
Actin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Phosphatidylserine Binding
Protein Tyrosine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Myosin Heavy Chain Binding
Phosphatidylinositol 3-kinase Binding
Protein Heterodimerization Activity
Biological Process
Protein Ubiquitination
Neuron Migration
Natural Killer Cell Differentiation
Positive Regulation Of Cytokine-mediated Signaling Pathway
Blood Vessel Remodeling
Phagocytosis
Inflammatory Response
Signal Transduction
Spermatogenesis
Peptidyl-tyrosine Phosphorylation
Forebrain Cell Migration
Platelet Activation
Organ Regeneration
Cellular Response To Extracellular Stimulus
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Natural Killer Cell Differentiation
Secretion By Cell
Erythrocyte Homeostasis
Substrate Adhesion-dependent Cell Spreading
Cellular Response To Interferon-alpha
Ovulation Cycle
Apoptotic Cell Clearance
Protein Kinase B Signaling
Negative Regulation Of Neuron Apoptotic Process
Innate Immune Response
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell Maturation
Negative Regulation Of Lymphocyte Activation
Positive Regulation Of Protein Kinase B Signaling
Vagina Development
Cellular Response To Hydrogen Peroxide
Cellular Response To Lipopolysaccharide
Dendritic Cell Differentiation
Negative Regulation Of Dendritic Cell Apoptotic Process
Pathways
Signaling by VEGF
VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions
80 interactors:
ADRBK1
ANKRD13A
APLF
AXL
BMX
C11orf63
C19orf57
C6orf106
C7orf50
CDK5RAP2
CDK9
CENPB
CUL1
CXXC4
DCX
DDX42
DEPTOR
DNAJB2
DNAJC8
DYRK3
DYRK4
EGFR
EID3
EIF4E2
ELK1
EPN1
FKBP3
G3BP1
GTF2B
GTF2IRD2
HIP1
HMCES
HP1BP3
IL21
ING3
IRS1
KDR
KRT8
LMCD1
LUC7L
MAT2B
NSRP1
NUAK1
ODF2
ORC4
PADI4
PAK4
PCK1
PDGFRA
PIP4K2C
PPID
PPP1R8
PRKCA
PRKG2
PRR15
PRRG1
PSMD4
RABEP2
RBM8A
RHBDD1
RIOK3
RPAP3
RPS10
RPS6KB2
SAMHD1
SERBP1
SKP1
STAC
SYTL2
TCEAL2
TCEANC
TCP10L
TMA7
TNIP2
TRUB1
TWF1
UBE2D3
UBQLN1
UBQLN2
WDSUB1
21 interactors:
ADAM10
CBL
FBXO25
GAS6
GRB2
IL15RA
IL2RG
LCK
NCK2
PIK3R1
PIK3R2
PIK3R3
PLCG1
PTPN11
RANBP9
SHC1
SHC3
SOCS1
SRC
TNS2
TYRO3
Entrez ID
26260
558
HPRD ID
16439
00171
Ensembl ID
ENSG00000147364
ENSG00000167601
Uniprot IDs
Q8TCJ0
M0R0W6
P30530
PDB IDs
2C5D
Enriched GO Terms of Interacting Partners
?
Regulation Of Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Peptidyl-amino Acid Modification
Cellular Metabolic Process
Cellular Protein Modification Process
Enzyme Linked Receptor Protein Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Response To Stress
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Innate Immune Response
Neurotrophin Signaling Pathway
Viral Process
Protein Phosphorylation
Cellular Response To Stimulus
Cellular Response To Growth Factor Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
Cellular Protein Metabolic Process
Response To Growth Factor
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Gene Expression
Peptidyl-tyrosine Phosphorylation
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Positive Regulation Of Phospholipase C Activity
Phosphorylation
Intracellular Signal Transduction
Regulation Of Cellular Process
Rhythmic Process
Protein Autophosphorylation
Positive Regulation Of Phospholipase Activity
Response To Stimulus
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Organic Substance
Immune Response
Proteasomal Protein Catabolic Process
G1/S Transition Of Mitotic Cell Cycle
Response To UV-A
Peptidyl-serine Autophosphorylation
Regulation Of Phospholipase Activity
Apoptotic Process
Positive Regulation Of Lipase Activity
Defense Response
Protein Metabolic Process
Regulation Of Cell Death
Immune System Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecule Catabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Leukocyte Migration
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Blood Coagulation
Hemostasis
Cellular Response To Organic Substance
Response To Peptide Hormone
Cellular Response To Organonitrogen Compound
Locomotion
Response To Organic Substance
Response To Peptide
Cell Surface Receptor Signaling Pathway
Regulation Of Immune System Process
Cellular Response To Insulin Stimulus
Regulation Of Body Fluid Levels
Cellular Response To Hormone Stimulus
Cell Migration
Wound Healing
Movement Of Cell Or Subcellular Component
Insulin Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Signal Transduction
Cell Motility
Response To Insulin
Response To Wounding
Regulation Of Phosphorylation
Immune System Process
Signaling
Platelet Activation
Cell Communication
Regulation Of Kinase Activity
Intracellular Signal Transduction
Regulation Of Phosphorus Metabolic Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Response To Organonitrogen Compound
Fc-epsilon Receptor Signaling Pathway
Regulation Of Lymphocyte Activation
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Tagcloud
?
antiapoptotic
ark
augmented
ax1
cascades
coincubation
erk
forebrain
gas6
gn10
gnrh
gt1
mek
migrating
olfactory
pd98059
phosphoinositide
pi3
postmigratory
programmed
protects
rescued
starved
threonine
tyro7
ufo
windows
withdrawal
wortmannin
Tagcloud (Difference)
?
antiapoptotic
ark
augmented
ax1
cascades
coincubation
erk
forebrain
gas6
gn10
gnrh
gt1
mek
migrating
olfactory
pd98059
phosphoinositide
pi3
postmigratory
programmed
protects
rescued
starved
threonine
tyro7
ufo
windows
withdrawal
wortmannin
Tagcloud (Intersection)
?