FBXO25 and CXXC4

Number of citations of the paper that reports this interaction (PMID 20473970)
1

Data Source:
BioGRID (two hybrid)

		FBXO25	CXXC4
Gene Name		F-box protein 25	CXXC finger protein 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex	Cytoplasm Cytoplasmic Membrane-bounded Vesicle Cytoplasmic Vesicle
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding	DNA Binding Zinc Ion Binding PDZ Domain Binding
	Biological Process	Protein Ubiquitination	Zygotic Specification Of Dorsal/ventral Axis Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1	3 interactors: APP DVL1 FBXO25
Entrez ID		26260	80319
HPRD ID		16439	16773
Ensembl ID		ENSG00000147364	ENSG00000168772
Uniprot IDs		Q8TCJ0	J9JIF5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process	Collateral Sprouting Neuromuscular Junction Development Developmental Cell Growth Neuromuscular Process Dendrite Development Developmental Growth Involved In Morphogenesis Regulation Of Protein Binding Cell Growth Synapse Organization Synaptic Growth At Neuromuscular Junction Convergent Extension Involved In Neural Plate Elongation Collateral Sprouting In Absence Of Injury Regulation Of Binding Developmental Growth Positive Regulation Of Proteolysis Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Convergent Extension Involved In Organogenesis Axon Choice Point Recognition Axon Guidance Protein Localization To Microtubule Neural Plate Morphogenesis Neuron Remodeling Skeletal Muscle Acetylcholine-gated Channel Clustering Growth Secretion By Cell Axonogenesis Regulation Of Neuron Differentiation Planar Cell Polarity Pathway Involved In Neural Tube Closure Axon Development Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Cell Morphogenesis Involved In Neuron Differentiation Convergent Extension Behavior Chemotaxis Prepulse Inhibition Neural Plate Development Secretion Neuron Projection Morphogenesis Cellular Copper Ion Homeostasis Regulation Of Proteolysis Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Neurogenesis Protein Localization To Cytoskeleton Cell Morphogenesis Involved In Differentiation Copper Ion Homeostasis Suckling Behavior Regulation Of Protein Kinase Activity Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule-based Process
Tagcloud ?			5q blast clinicopathological counts cytopenias eleven hemoglobin ipss marrow mds mrna multivariate myelodysplastic neutrophil qrt raeb rars rcmd regulator rs subsequently subtypes survival ten tet2 translocation u wnt
Tagcloud (Difference) ?			5q blast clinicopathological counts cytopenias eleven hemoglobin ipss marrow mds mrna multivariate myelodysplastic neutrophil qrt raeb rars rcmd regulator rs subsequently subtypes survival ten tet2 translocation u wnt
Tagcloud (Intersection) ?