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FBXO25 and RPS6KB2
Number of citations of the paper that reports this interaction (PMID
23940030
)
0
Data Source:
BioGRID
(enzymatic study)
FBXO25
RPS6KB2
Gene Name
F-box protein 25
ribosomal protein S6 kinase, 70kDa, polypeptide 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleolus
SCF Ubiquitin Ligase Complex
Nucleoplasm
Cytoplasm
Molecular Function
Actin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Ribosomal Protein S6 Kinase Activity
ATP Binding
Peptide Binding
Biological Process
Protein Ubiquitination
Translation
Protein Phosphorylation
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Protein Kinase B Signaling
Innate Immune Response
Positive Regulation Of Translational Initiation
Neurotrophin TRK Receptor Signaling Pathway
Phosphatidylinositol-mediated Signaling
Pathways
Signaling by the B Cell Receptor (BCR)
Signaling by FGFR in disease
PIP3 activates AKT signaling
Signaling by EGFRvIII in Cancer
Signaling by SCF-KIT
DAP12 signaling
Downstream signaling events of B Cell Receptor (BCR)
PI3K/AKT activation
PI-3K cascade
PI3K events in ERBB2 signaling
Downstream signaling of activated FGFR
Innate Immune System
Signaling by PDGF
DAP12 interactions
Signalling by NGF
GAB1 signalosome
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by ERBB4
Constitutive PI3K/AKT Signaling in Cancer
Role of LAT2/NTAL/LAB on calcium mobilization
PI3K events in ERBB4 signaling
Signaling by FGFR
Signaling by ERBB2
Signaling by EGFR
AKT phosphorylates targets in the nucleus
Downstream signal transduction
Fc epsilon receptor (FCERI) signaling
Signaling by EGFR in Cancer
PI3K/AKT Signaling in Cancer
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
80 interactors:
ADRBK1
ANKRD13A
APLF
AXL
BMX
C11orf63
C19orf57
C6orf106
C7orf50
CDK5RAP2
CDK9
CENPB
CUL1
CXXC4
DCX
DDX42
DEPTOR
DNAJB2
DNAJC8
DYRK3
DYRK4
EGFR
EID3
EIF4E2
ELK1
EPN1
FKBP3
G3BP1
GTF2B
GTF2IRD2
HIP1
HMCES
HP1BP3
IL21
ING3
IRS1
KDR
KRT8
LMCD1
LUC7L
MAT2B
NSRP1
NUAK1
ODF2
ORC4
PADI4
PAK4
PCK1
PDGFRA
PIP4K2C
PPID
PPP1R8
PRKCA
PRKG2
PRR15
PRRG1
PSMD4
RABEP2
RBM8A
RHBDD1
RIOK3
RPAP3
RPS10
RPS6KB2
SAMHD1
SERBP1
SKP1
STAC
SYTL2
TCEAL2
TCEANC
TCP10L
TMA7
TNIP2
TRUB1
TWF1
UBE2D3
UBQLN1
UBQLN2
WDSUB1
20 interactors:
ATP5A1
BRAF
BTK
COASY
CSNK2B
EEF2K
EP300
FBXO25
IKBKG
KAT2B
LYN
MAPK8IP2
MTOR
NEDD4L
PDPK1
PRKCE
RPS6
SRC
SRPK1
SYK
Entrez ID
26260
6199
HPRD ID
16439
10203
Ensembl ID
ENSG00000147364
ENSG00000175634
Uniprot IDs
Q8TCJ0
Q9UBS0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Peptidyl-amino Acid Modification
Cellular Metabolic Process
Cellular Protein Modification Process
Enzyme Linked Receptor Protein Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Response To Stress
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Innate Immune Response
Neurotrophin Signaling Pathway
Viral Process
Protein Phosphorylation
Cellular Response To Stimulus
Cellular Response To Growth Factor Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
Cellular Protein Metabolic Process
Response To Growth Factor
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Gene Expression
Peptidyl-tyrosine Phosphorylation
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Positive Regulation Of Phospholipase C Activity
Phosphorylation
Intracellular Signal Transduction
Regulation Of Cellular Process
Rhythmic Process
Protein Autophosphorylation
Positive Regulation Of Phospholipase Activity
Response To Stimulus
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Organic Substance
Immune Response
Proteasomal Protein Catabolic Process
G1/S Transition Of Mitotic Cell Cycle
Response To UV-A
Peptidyl-serine Autophosphorylation
Regulation Of Phospholipase Activity
Apoptotic Process
Positive Regulation Of Lipase Activity
Defense Response
Protein Metabolic Process
Regulation Of Cell Death
Immune System Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecule Catabolic Process
Regulation Of Protein Phosphorylation
Phosphorylation
Enzyme Linked Receptor Protein Signaling Pathway
Fc Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Phosphorylation
Regulation Of Protein Metabolic Process
Regulation Of Protein Kinase Activity
Phosphate-containing Compound Metabolic Process
Intracellular Signal Transduction
Regulation Of Kinase Activity
Viral Process
Regulation Of Phosphorus Metabolic Process
Innate Immune Response
Protein Autophosphorylation
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Phosphorylation
Response To Organic Substance
Cell Surface Receptor Signaling Pathway
Cellular Protein Modification Process
Response To Hormone
Immune Response
Protein Phosphorylation
Response To Peptide Hormone
Defense Response
Immune Response-regulating Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Protein Phosphorylation
Response To Insulin
Response To Peptide
Cellular Protein Metabolic Process
Cellular Response To Organic Substance
Signal Transduction
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Peptide
Response To Organonitrogen Compound
Cellular Response To Hormone Stimulus
Signaling
Positive Regulation Of Cell Adhesion
Positive Regulation Of Protein Metabolic Process
Cellular Response To Insulin Stimulus
Cell Communication
Positive Regulation Of Protein Modification Process
Immune System Process
Fc-epsilon Receptor Signaling Pathway
Peptidyl-amino Acid Modification
Peptidyl-tyrosine Autophosphorylation
Cell Activation
Cellular Metabolic Process
Tagcloud
?
administrated
arylnaphthalide
atg12
atg5
autophagic
bafilomycin
beclin
bnip3
chloroquine
inc
ja
justicia
justicidin
lc3
lignan
methyladenine
mrfp
p62
p70s6k
pdk1
periodicals
physiol
procumbens
ptflc3
puncta
shrna
sqstm1
vad
wiley
Tagcloud (Difference)
?
administrated
arylnaphthalide
atg12
atg5
autophagic
bafilomycin
beclin
bnip3
chloroquine
inc
ja
justicia
justicidin
lc3
lignan
methyladenine
mrfp
p62
p70s6k
pdk1
periodicals
physiol
procumbens
ptflc3
puncta
shrna
sqstm1
vad
wiley
Tagcloud (Intersection)
?