FBXO25 and C7orf50

Number of citations of the paper that reports this interaction (PMID 23940030)
0

Data Source:
BioGRID (enzymatic study)

		FBXO25	C7orf50
Gene Name		F-box protein 25	chromosome 7 open reading frame 50
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleolus SCF Ubiquitin Ligase Complex
	Molecular Function	Actin Binding Ubiquitin-protein Transferase Activity Protein Binding	Poly(A) RNA Binding
	Biological Process	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS			Longevity ( 20834067)
Protein-Protein Interactions		80 interactors: ADRBK1 ANKRD13A APLF AXL BMX C11orf63 C19orf57 C6orf106 C7orf50 CDK5RAP2 CDK9 CENPB CUL1 CXXC4 DCX DDX42 DEPTOR DNAJB2 DNAJC8 DYRK3 DYRK4 EGFR EID3 EIF4E2 ELK1 EPN1 FKBP3 G3BP1 GTF2B GTF2IRD2 HIP1 HMCES HP1BP3 IL21 ING3 IRS1 KDR KRT8 LMCD1 LUC7L MAT2B NSRP1 NUAK1 ODF2 ORC4 PADI4 PAK4 PCK1 PDGFRA PIP4K2C PPID PPP1R8 PRKCA PRKG2 PRR15 PRRG1 PSMD4 RABEP2 RBM8A RHBDD1 RIOK3 RPAP3 RPS10 RPS6KB2 SAMHD1 SERBP1 SKP1 STAC SYTL2 TCEAL2 TCEANC TCP10L TMA7 TNIP2 TRUB1 TWF1 UBE2D3 UBQLN1 UBQLN2 WDSUB1	6 interactors: APP CCDC85B FBXO25 NEDD4L PRNP THAP1
Entrez ID		26260	84310
HPRD ID		16439	14413
Ensembl ID		ENSG00000147364	ENSG00000146540
Uniprot IDs		Q8TCJ0	Q9BRJ6
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Peptidyl-amino Acid Modification Cellular Metabolic Process Cellular Protein Modification Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To Stress Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Innate Immune Response Neurotrophin Signaling Pathway Viral Process Protein Phosphorylation Cellular Response To Stimulus Cellular Response To Growth Factor Stimulus Fibroblast Growth Factor Receptor Signaling Pathway Cellular Protein Metabolic Process Response To Growth Factor Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Gene Expression Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Phospholipase C Activity Phosphorylation Intracellular Signal Transduction Regulation Of Cellular Process Rhythmic Process Protein Autophosphorylation Positive Regulation Of Phospholipase Activity Response To Stimulus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Immune Response Proteasomal Protein Catabolic Process G1/S Transition Of Mitotic Cell Cycle Response To UV-A Peptidyl-serine Autophosphorylation Regulation Of Phospholipase Activity Apoptotic Process Positive Regulation Of Lipase Activity Defense Response Protein Metabolic Process Regulation Of Cell Death Immune System Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process	Cellular Copper Ion Homeostasis Copper Ion Homeostasis Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Ion Homeostasis Cellular Homeostasis Positive Regulation Of Caveolin-mediated Endocytosis Synaptic Growth At Neuromuscular Junction Transition Metal Ion Homeostasis Collateral Sprouting In Absence Of Injury Negative Regulation Of Cellular Metabolic Process Chemical Homeostasis Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of RNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Copper Ion Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Axon Choice Point Recognition Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Calcium-mediated Signaling Learning Or Memory Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Tight Junction Assembly Cognition Neuron Remodeling Negative Regulation Of Interleukin-17 Production Regulation Of Calcineurin-NFAT Signaling Cascade Response To Metal Ion Negative Regulation Of Sodium Ion Transport Negative Regulation Of Activated T Cell Proliferation Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Sodium Ion Homeostasis Homeostatic Process Axon Guidance RNA Metabolic Process
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