SERBP1

Description		SERPINE1 mRNA binding protein 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Repressor Activity SUMO Binding Ribosome Binding Cadherin Binding Translation Elongation Factor Binding
	Biological Process	Regulation Of Translation Negative Regulation Of Translation PML Body Organization Regulation Of MRNA Stability Ribosome Hibernation
Pathways
Drugs
Diseases
GWAS		Bone mineral density (hip) ( 30172743) Carotid plaque burden ( 28282560) Crohn's disease ( 22412388 28067908) DHEAS levels ( 34748635) Inflammatory bowel disease ( 28067908) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 28067908)
Novel Interacting Genes		1 novel interacting genes: TSPAN15
Interacting Genes		27 interacting genes: - APP CHD3 CSNK2A1 DANCR DAXX ESR1 FBXO25 FXYD3 H19 KAT2B LINC00624 OGT PIAS1 PIAS3 PIAS4 PICK1 PRMT8 TDG TERT TOPORS UBA2 UPF2 USP7 VAV2 VIM WEE2-AS1
Entrez ID		26135
HPRD ID		09570
Ensembl ID		ENSG00000142864
Uniprot IDs		Q5VU21 Q8NC51
PDB IDs		4V6X 6Z6M 6Z6N 8K2C 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X
Enriched GO Terms of Interacting Partners?		PML Body Positive Regulation Of Protein Sumoylation Protein Sumoylation SUMO Transferase Activity Regulation Of Protein Sumoylation SUMO Ligase Activity Transcription Coregulator Activity Regulation Of Post-translational Protein Modification Chromatin Organization Chromatin Remodeling Negative Regulation Of Gene Expression Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Proteolysis Regulation Of Protein Catabolic Process Protein Modification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Enzyme Binding Positive Regulation Of Transcription By Glucose Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Rhythmic Process Carbon Catabolite Regulation Of Transcription Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Metabolic Process Positive Regulation Of Post-translational Protein Modification Regulation Of Programmed Cell Death Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Macromolecule Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Gene Expression, Epigenetic Regulation Of Primary Metabolic Process Regulation Of Glycolytic Process Regulation Of Protein Metabolic Process Regulation Of Gluconeogenesis Protein Modification By Small Protein Conjugation Regulation Of Transcription By Glucose Regulation Of Macromolecule Metabolic Process Cellular Response To Stress
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