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FBXO25 and STAC
Number of citations of the paper that reports this interaction (PMID
23940030
)
0
Data Source:
BioGRID
(enzymatic study)
FBXO25
STAC
Gene Name
F-box protein 25
SH3 and cysteine rich domain
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleolus
SCF Ubiquitin Ligase Complex
Cytosol
Molecular Function
Actin Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Protein Binding
Metal Ion Binding
Biological Process
Protein Ubiquitination
Signal Transduction
Cellular Response To Heat
Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS
Erectile dysfunction (
22704111
)
Protein-Protein Interactions
80 interactors:
ADRBK1
ANKRD13A
APLF
AXL
BMX
C11orf63
C19orf57
C6orf106
C7orf50
CDK5RAP2
CDK9
CENPB
CUL1
CXXC4
DCX
DDX42
DEPTOR
DNAJB2
DNAJC8
DYRK3
DYRK4
EGFR
EID3
EIF4E2
ELK1
EPN1
FKBP3
G3BP1
GTF2B
GTF2IRD2
HIP1
HMCES
HP1BP3
IL21
ING3
IRS1
KDR
KRT8
LMCD1
LUC7L
MAT2B
NSRP1
NUAK1
ODF2
ORC4
PADI4
PAK4
PCK1
PDGFRA
PIP4K2C
PPID
PPP1R8
PRKCA
PRKG2
PRR15
PRRG1
PSMD4
RABEP2
RBM8A
RHBDD1
RIOK3
RPAP3
RPS10
RPS6KB2
SAMHD1
SERBP1
SKP1
STAC
SYTL2
TCEAL2
TCEANC
TCP10L
TMA7
TNIP2
TRUB1
TWF1
UBE2D3
UBQLN1
UBQLN2
WDSUB1
11 interactors:
APP
C9orf156
FBXO25
KANK2
KIAA1958
LIMD1
LMNA
LZTS2
NCKIPSD
NEDD4L
TRIP6
Entrez ID
26260
6769
HPRD ID
16439
11890
Ensembl ID
ENSG00000147364
ENSG00000144681
Uniprot IDs
Q8TCJ0
E9PEA7
Q99469
PDB IDs
2DL4
Enriched GO Terms of Interacting Partners
?
Regulation Of Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Peptidyl-amino Acid Modification
Cellular Metabolic Process
Cellular Protein Modification Process
Enzyme Linked Receptor Protein Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Response To Stress
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Innate Immune Response
Neurotrophin Signaling Pathway
Viral Process
Protein Phosphorylation
Cellular Response To Stimulus
Cellular Response To Growth Factor Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
Cellular Protein Metabolic Process
Response To Growth Factor
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Gene Expression
Peptidyl-tyrosine Phosphorylation
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Positive Regulation Of Phospholipase C Activity
Phosphorylation
Intracellular Signal Transduction
Regulation Of Cellular Process
Rhythmic Process
Protein Autophosphorylation
Positive Regulation Of Phospholipase Activity
Response To Stimulus
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Organic Substance
Immune Response
Proteasomal Protein Catabolic Process
G1/S Transition Of Mitotic Cell Cycle
Response To UV-A
Peptidyl-serine Autophosphorylation
Regulation Of Phospholipase Activity
Apoptotic Process
Positive Regulation Of Lipase Activity
Defense Response
Protein Metabolic Process
Regulation Of Cell Death
Immune System Process
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Cellular Macromolecule Catabolic Process
Regulation Of Signal Transduction
Negative Regulation Of Signal Transduction
Regulation Of Signaling
Negative Regulation Of Signaling
Regulation Of Protein Localization To Nucleus
Nucleocytoplasmic Transport
Nuclear Transport
Regulation Of Protein Localization
Sterol Regulatory Element Binding Protein Import Into Nucleus
Regulation Of Cellular Localization
Response To Abiotic Stimulus
Cytoskeleton Organization
Negative Regulation Of Vitamin D Receptor Signaling Pathway
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Caveolin-mediated Endocytosis
Protein Import Into Nucleus
Nuclear Import
Collateral Sprouting In Absence Of Injury
Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity
Signal Transduction
Positive Regulation Of Gene Silencing By MiRNA
Negative Regulation Of Canonical Wnt Signaling Pathway
Protein Import
Release Of Cytoplasmic Sequestered NF-kappaB
Collateral Sprouting
Axon Midline Choice Point Recognition
Protein Localization To Nucleus
Regulation Of Vitamin D Receptor Signaling Pathway
Negative Regulation Of Sodium Ion Transmembrane Transporter Activity
Negative Regulation Of Hippo Signaling
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Regulation Of Caveolin-mediated Endocytosis
Signaling
Regulation Of Cellular Component Movement
Cytoplasmic Transport
Intracellular Transport
Cell Communication
Axon Choice Point Recognition
Negative Regulation Of Sodium Ion Transmembrane Transport
Negative Regulation Of Wnt Signaling Pathway
Microtubule-based Process
Negative Regulation Of Protein Localization To Cell Surface
Negative Regulation Of Potassium Ion Transmembrane Transporter Activity
Regulation Of Tight Junction Assembly
Regulation Of Hippo Signaling
Positive Regulation Of Cell Aging
Regulation Of Transcription, DNA-templated
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Nucleic Acid-templated Transcription
Tagcloud
?
17p
1p36
1q
1q13
1q21
4q21
7p
7q
8p
8q
8q11
9p
aspscr1
cirrhotic
etv1and
ffpe
fgfr3
gains
hcc
hccs
maf
nearby
pathologically
pter
q23
q26
recql4
xp
xq
Tagcloud (Difference)
?
17p
1p36
1q
1q13
1q21
4q21
7p
7q
8p
8q
8q11
9p
aspscr1
cirrhotic
etv1and
ffpe
fgfr3
gains
hcc
hccs
maf
nearby
pathologically
pter
q23
q26
recql4
xp
xq
Tagcloud (Intersection)
?