YWHAQ and CBL

  • Number of citations of the paper that reports this interaction (PMID 9092538)
  • 23
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vivo, in vitro)

YWHAQ

CBL

Gene Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta Cbl proto-oncogene, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Heart rate variability traits ( 22174390)
Protein-Protein Interactions 231 interactors: AARS2 ABL1 ACSL4 AHCY AKT1S1 ANXA1 ANXA2 APC AR ARHGAP10 ARHGEF16 ATP5A1 BAD BAX BCAP31 BCR BRAF CABIN1 CAPN3 CBL CBLL1 CDC25A CDC25B CDC25C CDC5L CDK11B CDK14 CDK16 CDK17 CDK18 CDKN1A CDKN1B CEP170 CFL1 CHAF1A CKM CLTC COPS4 CSE1L CSNK1A1 CSNK2A1 CTPS1 DAB2IP DCPS DDX1 DDX3X DHX9 DISC1 DNMT1 DYNC1H1 E2F1 EFNB1 EIF4A3 ENO1 EPB41 EPB41L1 EPB41L3 ESR1 ESR2 EXO1 FASN FBLN1 FGR FSCN1 FSHR FXYD1 GAPDH GCN1L1 HADHA HAT1 HAX1 HDAC4 HDAC5 HDAC7 HIST1H2BG HIST2H4A HNRNPA1 HNRNPC HNRNPF HNRNPH1 HNRNPK HSPA1A HSPA8 HUS1 IARS2 ING1 IQGAP1 IRS2 ITGB4 KCNK15 KCNK3 KCNK9 KIAA1429 KIF1C KIF23 KIF5B KLC2 KLC3 KRT1 KRT9 LARP1 LARS2 LDHA LIMA1 LMNA LMNB1 LMO7 LYST MAGOH MAP3K3 MAP3K5 MARK2 MARK3 MCM3 MDM4 MED1 MEF2D MPL MPRIP MRPS27 MST1R MTNR1B MTOR MYCBP2 NADK NCL NCOA1 NCOA3 NDE1 NFATC1 NFATC2 NFATC4 NFKB1 NIF3L1 NME7 NOLC1 NUMA1 PABPC4 PABPN1 PAK4 PANK1 PCM1 PDCD6 PDE3A PDE3B PDK1 PDPK1 PDXK PFKFB2 PFKL PFN1 PGK1 PHLDB2 PI4KB PIK3C2B PIK3C3 PIK3CB PKM PPFIBP1 PRDX1 PRKCQ PRKCZ PRKD1 PRKDC PRMT5 PSME3 PTPN3 RAF1 RAI14 RCOR3 REM1 RFC1 RGS3 RGS7 RNASE2 RPL10A RPL15 RPL19 RPL7 RPLP0 RPLP2 RPS3 RUVBL2 SAMSN1 SH3BP2 SLC27A2 SLC8A1 SLC8A2 SLC8A3 SMAD9 SNRPE SPR SPTA1 SPTB SRSF3 SSBP1 SSFA2 SSX2IP TCP1 TERT THRA TLN1 TNF TNFAIP3 TP53BP2 TPI1 TPR TRIM28 TRIM42 TSC1 TSC2 TUBA1A TUBA3C TUBB UBQLN4 UCP2 UCP3 ULK4 USP8 VARS WDR61 WDR77 WEE1 WTAP WWC2 WWP1 YAP1 YWHAE YWHAG ZC3H13 ZHX2 114 interactors: ABL1 ASAP1 AXL BCR BLK BLNK BTK CAPN1 CD19 CD2AP CD38 CD40 CD5 CDKL2 CRK CRKL CSF1R CTNNB1 CUBN EGFR EIF5B EPHA2 EPHB6 EPOR ERBB2 F2RL1 FGR FLOT1 FLT3 FNBP1 FRS2 FYB FYN GIF GRB2 HCK IGF1R INPPL1 INSR ITCH ITK ITSN2 KDR KHDRBS1 KIT KRT18 LAT LAT2 LCK LCP2 LRIG1 LTK LYN MAPK8 MET MYH9 MYO1C NCK1 NOTCH1 OSTF1 PDGFRA PDGFRB PIK3R1 PIK3R2 PLCG1 PRKCA PRKCQ PTK2B PTPN11 PTPN22 PTPN6 RET SCN5A SH2B2 SH3KBP1 SHC1 SLA SLA2 SORBS1 SORBS2 SPRY2 SRC STAP2 STAT5A STAT5B SYK TCN1 TCN2 TGFBR2 TNFRSF11A TNS4 TRAF4 TRAF6 TRIM8 TYK2 UBASH3A UBASH3B UBC UBE2D1 UBE2D2 UBE2D3 UBE2G1 UBE2G2 UBE2L3 UBE2M USP21 VAV1 VAV2 YES1 YWHAB YWHAG YWHAQ YWHAZ ZAP70
Entrez ID 10971 867
HPRD ID 00886 01320
Ensembl ID ENSG00000134308 ENSG00000110395
Uniprot IDs B4DMT8 P27348 P22681
PDB IDs 2BTP 1B47 1FBV 1YVH 2CBL 2JUJ 2K4D 2OO9 2Y1M 2Y1N 3BUM 3BUN 3BUO 3BUW 3BUX 3OB1 3OB2 3PLF 4A49 4A4B 4A4C 4GPL
Enriched GO Terms of Interacting Partners?
Tagcloud ?
32dcl3  32p  antisera  eliminated  engagement  fusion  fyn  gst  hck  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
Tagcloud (Difference) ?
32dcl3  32p  antisera  eliminated  engagement  fusion  fyn  gst  hck  immunoprecipitated  immunoprecipitates  implying  lyn  lysate  lzip  nb2  nonphosphorylated  p85  phosphatidylinositol  phosphorylate  phosphoserine  phosphothreonine  phosphotyrosine  proline  sh2  sh3  thymoma  tyr731  yeam 
Tagcloud (Intersection) ?