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YWHAQ and BAX
Number of citations of the paper that reports this interaction (PubMedID
24055994
)
0
Data Source:
BioGRID
(genetic interference, pull down)
HPRD
(in vitro, in vivo)
YWHAQ
BAX
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
BCL2 associated X, apoptosis regulator
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Nucleus
Nuclear Envelope
Cytoplasm
Mitochondrion
Mitochondrial Outer Membrane
Mitochondrial Permeability Transition Pore Complex
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytosol
Membrane
Mitochondrial Membrane
Pore Complex
Extracellular Exosome
Cell Periphery
Bcl-2 Family Protein Complex
BAX Complex
BAK Complex
Molecular Function
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Transmembrane Transporter Binding
14-3-3 Protein Binding
Protein Binding
Lipid Binding
Channel Activity
Hsp70 Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Protein-folding Chaperone Binding
BH3 Domain Binding
Biological Process
Protein Targeting
Signal Transduction
Small GTPase-mediated Signal Transduction
Intracellular Protein Localization
Substantia Nigra Development
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of DNA-templated Transcription
Ovarian Follicle Development
Neuron Migration
Leukocyte Homeostasis
T Cell Homeostatic Proliferation
B Cell Homeostasis
B Cell Apoptotic Process
Kidney Development
Release Of Cytochrome C From Mitochondria
Blood Vessel Remodeling
Myeloid Cell Homeostasis
B Cell Negative Selection
B Cell Homeostatic Proliferation
Positive Regulation Of B Cell Apoptotic Process
Glycosphingolipid Metabolic Process
Regulation Of Nitrogen Utilization
Apoptotic Process
DNA Damage Response
Mitochondrion Organization
Germ Cell Development
Spermatogenesis
Nervous System Development
Sex Differentiation
Mitochondrial Fusion
Cell Population Proliferation
Negative Regulation Of Cell Population Proliferation
Male Gonad Development
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Apoptotic Mitochondrial Changes
Fertilization
Response To Wounding
Response To Toxic Substance
Response To Salt Stress
Post-embryonic Development
Response To Ionizing Radiation
Establishment Or Maintenance Of Transmembrane Electrochemical Gradient
Response To Gamma Radiation
Positive Regulation Of Calcium Ion Transport Into Cytosol
Negative Regulation Of Mitochondrial Membrane Potential
Hypothalamus Development
Cerebral Cortex Development
Positive Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Protein Binding
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Release Of Matrix Enzymes From Mitochondria
Cellular Response To Stress
Regulation Of Mammary Gland Epithelial Cell Proliferation
Cellular Response To Unfolded Protein
Cellular Response To UV
Limb Morphogenesis
Ectopic Germ Cell Programmed Cell Death
Odontogenesis Of Dentin-containing Tooth
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Regulation Of Neuron Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of Neuron Apoptotic Process
Mitochondrial Fragmentation Involved In Apoptotic Process
Development Of Secondary Sexual Characteristics
Retinal Cell Programmed Cell Death
Positive Regulation Of Developmental Pigmentation
Negative Regulation Of Fibroblast Proliferation
Spermatid Differentiation
Post-embryonic Camera-type Eye Morphogenesis
Response To Axon Injury
Homeostasis Of Number Of Cells
Homeostasis Of Number Of Cells Within A Tissue
Epithelial Cell Proliferation
Positive Regulation Of Developmental Process
Protein Insertion Into Mitochondrial Membrane
Release Of Sequestered Calcium Ion Into Cytosol
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Neuron Apoptotic Process
Establishment Of Localization In Cell
Regulation Of Cell Cycle
Regulation Of Mitochondrial Membrane Potential
Sertoli Cell Proliferation
Retina Development In Camera-type Eye
Apoptotic Process Involved In Mammary Gland Involution
Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution
Vagina Development
Calcium Ion Transport Into Cytosol
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Thymocyte Apoptotic Process
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Motor Neuron Apoptotic Process
Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Intrinsic Apoptotic Signaling Pathway
Execution Phase Of Apoptosis
Supramolecular Fiber Organization
Cellular Response To Virus
Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Apoptotic Process Involved In Blood Vessel Morphogenesis
Apoptotic Process Involved In Embryonic Digit Morphogenesis
Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death
Positive Regulation Of Apoptotic DNA Fragmentation
Regulation Of Intracellular Signal Transduction
Positive Regulation Of IRE1-mediated Unfolded Protein Response
Epithelial Cell Apoptotic Process
Positive Regulation Of Epithelial Cell Apoptotic Process
B Cell Receptor Apoptotic Signaling Pathway
Positive Regulation Of Reproductive Process
Positive Regulation Of Motor Neuron Apoptotic Process
Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Release of apoptotic factors from the mitochondria
Activation, translocation and oligomerization of BAX
Pyroptosis
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
Transcriptional regulation by RUNX2
NTRK3 as a dependence receptor
Drugs
Phenethyl Isothiocyanate
TAK-901
Diseases
Colorectal cancer
GWAS
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Asthma (
27611488
)
Eosinophil count (
27863252
32888494
)
Eosinophil percentage of white cells (
32888494
)
Lymphocyte count (
32888494
)
Neutrophil percentage of granulocytes (
27863252
)
Plateletcrit (
32888494
)
Sum eosinophil basophil counts (
27863252
)
White blood cell count (
32888494
)
Interacting Genes
216 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
AR
ARHGAP10
ARHGEF16
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDKN1A
CDKN1B
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC7
HNRNPC
HNRNPH1
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
ITCH
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LYST
MAGOH
MAP3K3
MAP3K5
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NEDD4L
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PANK1
PDCD6
PDE3A
PDE3B
PDE4B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C3
PIK3CB
PKM
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RIPK2
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SKIC8
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR77
WTAP
WWC2
WWP1
YAP1
YWHAG
ZC3H13
ZHX2
30 interacting genes:
ANP32B
BAK1
BBC3
BCL2
BCL2A1
BCL2L1
BCL2L10
BID
ERN1
FBXL20
HSF2BP
KCNA3
LEF1
MAP2K1
MCL1
MOAP1
NOL3
PARK7
PMAIP1
PPP1CA
SFN
SH3GLB1
SLC25A4
TRIM17
UHRF2
USP12
VDAC1
YWHAB
YWHAQ
ZBTB24
Entrez ID
10971
581
HPRD ID
00886
02498
Ensembl ID
ENSG00000134308
ENSG00000087088
Uniprot IDs
P27348
I6LPK7
Q07812
Q5ZPJ0
Q5ZPJ1
PDB IDs
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
1F16
2G5B
2K7W
2LR1
3PK1
3PL7
4BD2
4BD6
4BD7
4BD8
4BDU
4S0O
4S0P
4UF2
4ZIE
4ZIF
4ZIG
4ZIH
4ZII
5W5X
5W5Z
5W60
5W61
6EB6
6L8V
6L95
6TRR
6XY6
7ADT
8G1T
8SPE
8SPF
8SPZ
8SRX
8SRY
8SVK
Enriched GO Terms of Interacting Partners
?
Cytosol
Cytoplasm
Regulation Of Signaling
Regulation Of Cell Communication
Intracellular Signal Transduction
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Protein Metabolic Process
ATP Binding
Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Metabolic Process
Nucleus
Cadherin Binding
Kinase Activity
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Nucleotide Binding
Regulation Of Biological Quality
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cortex
Cellular Response To Oxygen-containing Compound
Response To Stress
Protein-containing Complex
Glucose Catabolic Process
Organelle Organization
Positive Regulation Of Multicellular Organismal Process
Macromolecule Metabolic Process
ADP Metabolic Process
RNA Binding
Cellular Response To Lipid
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Extracellular Exosome
Regulation Of Organelle Organization
Positive Regulation Of Cell Population Proliferation
Glycolytic Process
Cellular Response To Hormone Stimulus
Release Of Cytochrome C From Mitochondria
Apoptotic Mitochondrial Changes
Mitochondrion Organization
Intrinsic Apoptotic Signaling Pathway
Mitochondrial Outer Membrane
Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Regulation Of Release Of Cytochrome C From Mitochondria
Regulation Of Apoptotic Process
Regulation Of Apoptotic Signaling Pathway
Bcl-2 Family Protein Complex
Regulation Of Programmed Cell Death
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Apoptotic Process
Regulation Of Mitochondrial Membrane Permeability
Programmed Cell Death
Cell Death
DNA Damage Response
Mitochondrial Membrane Organization
Regulation Of Mitochondrion Organization
Extrinsic Apoptotic Signaling Pathway
Regulation Of Membrane Permeability
Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Apoptotic Process
Channel Activity
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Apoptotic Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Autophagy
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Response To Stress
Cellular Response To Stress
Mitochondrion
Regulation Of Mitochondrial Membrane Potential
Intracellular Signal Transduction
Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Cellular Response To Stress
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Mitochondrial Membrane Permeability
Negative Regulation Of Membrane Permeability
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
BH3 Domain Binding
Organelle Organization
Positive Regulation Of Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Autophagy
Mitochondrial Membrane
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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