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YWHAQ and FBLN1
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
YWHAQ
FBLN1
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
fibulin 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Extracellular Region
Basement Membrane
Extracellular Space
Extracellular Matrix
Extracellular Exosome
Elastic Fiber
Molecular Function
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Transmembrane Transporter Binding
14-3-3 Protein Binding
Fibronectin Binding
Integrin Binding
Extracellular Matrix Structural Constituent
Calcium Ion Binding
Protein Binding
Peptidase Activator Activity
Identical Protein Binding
Protein-containing Complex Binding
Fibrinogen Binding
Biological Process
Protein Targeting
Signal Transduction
Small GTPase-mediated Signal Transduction
Intracellular Protein Localization
Substantia Nigra Development
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Protein Phosphorylation
Negative Regulation Of Cell Adhesion
Integrin-mediated Signaling Pathway
Embryo Implantation
Positive Regulation Of Gene Expression
Extracellular Matrix Organization
Positive Regulation Of Fibroblast Proliferation
Negative Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Transforming Growth Factor Beta Production
Blood Coagulation, Fibrin Clot Formation
Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Transformation Of Host Cell By Virus
Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate
Negative Regulation Of Cell Motility
Negative Regulation Of Stem Cell Proliferation
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Molecules associated with elastic fibres
Molecules associated with elastic fibres
Drugs
Phenethyl Isothiocyanate
Diseases
Synpolydactyly, 3/3'4, associated with metacarpal and metatarsal synostoses
GWAS
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Blood protein levels (
30072576
)
Colon cancer (
33632709
)
Distal colorectal cancer (
33632709
)
Femur bone mineral density x serum urate levels interaction (
34046847
)
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Low density lipoprotein cholesterol levels (
32154731
)
Paneth cell defects in Crohn's disease (
28352666
)
Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) (
33987465
)
QT interval (
29213071
)
Red blood cell count (
27863252
)
Temperament (bipolar disorder) (
22365631
)
Interacting Genes
216 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
AR
ARHGAP10
ARHGEF16
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDKN1A
CDKN1B
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC7
HNRNPC
HNRNPH1
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
ITCH
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LYST
MAGOH
MAP3K3
MAP3K5
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NEDD4L
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PANK1
PDCD6
PDE3A
PDE3B
PDE4B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C3
PIK3CB
PKM
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RIPK2
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SKIC8
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR77
WTAP
WWC2
WWP1
YAP1
YWHAG
ZC3H13
ZHX2
66 interacting genes:
ACAN
ADAMTSL2
ADAMTSL4
AK3
ALG10
APOA1
APP
ATN1
BHLHE40
CACNA1A
CCN2
CCN3
CHIC2
CREB5
CRIPTO
CXCL5
DDIAS
ECM1
EDC4
ELN
FGB
FN1
FXR1
GFI1B
HBEGF
HOXA1
HSPG2
ITGB1
KLHL20
KRTAP11-1
KRTAP19-2
LCE1A
LCE1B
LCE1C
LCE1D
LCE1F
LCE3A
LCE5A
LINGO1
LMNTD2
LTBP4
MCPH1
MEOX2
MFAP5
MOB4
MRPL12
NEDD1
NID1
NLGN3
NOTCH3
NUFIP2
PAX5
PLSCR1
PPARA
SKIL
SLC66A2
SMAD3
SMAD4
SPRY1
TAF9
TANK
TCF7L2
TRIM42
UNKL
VCAN
YWHAQ
Entrez ID
10971
2192
HPRD ID
00886
00629
Ensembl ID
ENSG00000134308
ENSG00000077942
Uniprot IDs
P27348
A0A8S0LWY1
P23142
Q8NBH6
PDB IDs
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
Enriched GO Terms of Interacting Partners
?
Cytosol
Cytoplasm
Regulation Of Signaling
Regulation Of Cell Communication
Intracellular Signal Transduction
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Protein Metabolic Process
ATP Binding
Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Metabolic Process
Nucleus
Cadherin Binding
Kinase Activity
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Nucleotide Binding
Regulation Of Biological Quality
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cortex
Cellular Response To Oxygen-containing Compound
Response To Stress
Protein-containing Complex
Glucose Catabolic Process
Organelle Organization
Positive Regulation Of Multicellular Organismal Process
Macromolecule Metabolic Process
ADP Metabolic Process
RNA Binding
Cellular Response To Lipid
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Extracellular Exosome
Regulation Of Organelle Organization
Positive Regulation Of Cell Population Proliferation
Glycolytic Process
Cellular Response To Hormone Stimulus
Extracellular Matrix
Tissue Development
Epidermis Development
Keratinization
Extracellular Matrix Structural Constituent
Developmental Process
Integrin Binding
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of MiRNA Transcription
Regulation Of Signal Transduction
Response To Interleukin-1
Extracellular Matrix Structural Constituent Conferring Compression Resistance
Regulation Of Intracellular Signal Transduction
Developmental Growth
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Endothelial Cell Migration
Negative Regulation Of Signal Transduction
Regulation Of MiRNA Metabolic Process
Angiogenesis
Regulation Of Cell Communication
Regulation Of Signaling
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Extracellular Matrix Organization
Extracellular Structure Organization
Cell-matrix Adhesion
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of System Process
Anatomical Structure Formation Involved In Morphogenesis
Protein Binding
Negative Regulation Of Transcription By RNA Polymerase II
Animal Organ Development
Calcium-independent Cell-matrix Adhesion
Embryonic Pattern Specification
Adrenal Gland Development
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Identical Protein Binding
Extracellular Region
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Collagen Binding
Positive Regulation Of Cell-substrate Adhesion
Negative Regulation Of MiRNA Transcription
Cell Migration
Regulation Of Spontaneous Synaptic Transmission
Activin Receptor Signaling Pathway
Negative Regulation Of Macromolecule Metabolic Process
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Tagcloud (Difference)
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Tagcloud (Intersection)
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