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YWHAQ and H2BC8
Number of citations of the paper that reports this interaction (PubMedID
15161933
)
0
Data Source:
BioGRID
(pull down)
YWHAQ
H2BC8
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
H2B clustered histone 8
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Nucleosome
Extracellular Space
Nucleus
Nucleoplasm
Chromosome
Cytosol
Extracellular Exosome
Molecular Function
Protein Binding
Protein Domain Specific Binding
Identical Protein Binding
Transmembrane Transporter Binding
14-3-3 Protein Binding
DNA Binding
Protein Binding
Structural Constituent Of Chromatin
Identical Protein Binding
Protein Heterodimerization Activity
Biological Process
Protein Targeting
Signal Transduction
Small GTPase-mediated Signal Transduction
Intracellular Protein Localization
Substantia Nigra Development
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Negative Regulation Of DNA-templated Transcription
Innate Immune Response In Mucosa
Nucleosome Assembly
Antibacterial Humoral Response
Defense Response To Bacterium
Defense Response To Gram-positive Bacterium
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
HDACs deacetylate histones
HATs acetylate histones
HATs acetylate histones
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Ub-specific processing proteases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
Deposition of new CENPA-containing nucleosomes at the centromere
Assembly of the ORC complex at the origin of replication
G2/M DNA damage checkpoint
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
E3 ubiquitin ligases ubiquitinate target proteins
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Inhibition of DNA recombination at telomere
Defective pyroptosis
Negative Regulation of CDH1 Gene Transcription
Amyloid fiber formation
Chromatin modifications during the maternal to zygotic transition (MZT)
Replacement of protamines by nucleosomes in the male pronucleus
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by KRAB-ZFP proteins
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Regulation of PD-L1(CD274) transcription
Drugs
Phenethyl Isothiocyanate
Copper
Diseases
GWAS
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Interacting Genes
216 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
AR
ARHGAP10
ARHGEF16
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDKN1A
CDKN1B
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC7
HNRNPC
HNRNPH1
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
ITCH
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LYST
MAGOH
MAP3K3
MAP3K5
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NEDD4L
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PANK1
PDCD6
PDE3A
PDE3B
PDE4B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C3
PIK3CB
PKM
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RIPK2
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SKIC8
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR77
WTAP
WWC2
WWP1
YAP1
YWHAG
ZC3H13
ZHX2
7 interacting genes:
AP2M1
ESR1
PTMA
RAD51B
TGM2
UBR2
YWHAQ
Entrez ID
10971
8339
HPRD ID
00886
11897
Ensembl ID
ENSG00000134308
ENSG00000273802
Uniprot IDs
P27348
B2R4S9
P62807
PDB IDs
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
5GT0
5KGF
6ACO
6C0W
6FML
6R0C
6RNY
6SE0
6SE6
6SEE
6SEF
6SEG
6UPK
6UPL
6X59
6X5A
6XJD
7A08
7JO9
7JOA
7PII
7R5R
7TAN
7TRF
7U46
7U47
7U4D
7U50
7U51
7U52
7U53
7UV9
7Y8R
7YWX
7YYH
8ATF
8AV6
8JBX
8OFF
8OO7
8OOA
8OOP
8OOS
8OX0
8OX1
8QZM
8TXV
8TXW
8TXX
8U13
8VWS
8VWT
8VWU
8VWV
8X15
8X19
8X1C
9DWF
9DWG
9DWH
9DWI
9DWJ
9DWK
9DWL
9DWM
9EOZ
Enriched GO Terms of Interacting Partners
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Cytosol
Cytoplasm
Regulation Of Signaling
Regulation Of Cell Communication
Intracellular Signal Transduction
Regulation Of Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Regulation Of Protein Metabolic Process
ATP Binding
Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Negative Regulation Of Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Metabolic Process
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of Metabolic Process
Nucleus
Cadherin Binding
Kinase Activity
Negative Regulation Of Programmed Cell Death
Regulation Of Developmental Process
Nucleobase-containing Compound Metabolic Process
Cellular Response To Stress
Nucleotide Binding
Regulation Of Biological Quality
Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cell Cortex
Cellular Response To Oxygen-containing Compound
Response To Stress
Protein-containing Complex
Glucose Catabolic Process
Organelle Organization
Positive Regulation Of Multicellular Organismal Process
Macromolecule Metabolic Process
ADP Metabolic Process
RNA Binding
Cellular Response To Lipid
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Extracellular Exosome
Regulation Of Organelle Organization
Positive Regulation Of Cell Population Proliferation
Glycolytic Process
Cellular Response To Hormone Stimulus
14-3-3 Protein Binding
Reciprocal Meiotic Recombination
Homologous Recombination
Chromatin Organization
Peptide Dopaminyltransferase Activity
Histone Serotonyltransferase Activity
Peptide Histaminyltransferase Activity
Protein-glutamine Glutaminase Activity
Peptide Noradrenalinyltransferase Activity
Peptide Serotonyltransferase Activity
Histone Dopaminyltransferase Activity
Histone H2A Ubiquitin Ligase Activity
Transmembrane Transporter Binding
Signal Sequence Binding
Extrinsic Component Of Presynaptic Endocytic Zone Membrane
Nuclear Estrogen Receptor Activity
Regulation Of Branching Involved In Prostate Gland Morphogenesis
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Morphogenesis Of A Branching Structure
TFIIB-class Transcription Factor Binding
Prostate Epithelial Cord Elongation
Morphogenesis Of A Branching Epithelium
Positive Regulation Of Nitric-oxide Synthase Activity
Chromatin Remodeling
Mammary Gland Branching Involved In Pregnancy
Antral Ovarian Follicle Growth
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Rad51B-Rad51C-Rad51D-XRCC2 Complex
Protein Deamination
Cellular Response To Serotonin
Salivary Gland Cavitation
Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Positive Regulation Of Synaptic Vesicle Endocytosis
Positive Regulation Of Synaptic Vesicle Recycling
Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis
Regulation Of Nitric-oxide Synthase Activity
Blastocyst Growth
Dopamine Secretion
Cellular Response To Dopamine
Positive Regulation Of Mitochondrial Calcium Ion Concentration
Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration
Protein-glutamine Gamma-glutamyltransferase Activity
L-leucine Binding
Postsynaptic Neurotransmitter Receptor Internalization
Nitric-oxide Synthase Regulator Activity
Response To Dopamine
Catecholamine Secretion
Cellular Response To Oxygen-containing Compound
Prostate Gland Growth
Vagina Development
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Tagcloud (Intersection)
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